Navigation Links
Less reaction to DTaP vaccine given in kids' thighs than arms

SEATTLEChildren age 12 to 35 months who receive DTaP vaccine in their thigh muscle rather than their arm are around half as likely to be brought in for medical attention for an injection-site reaction. So says a new study of 1.4 million children at Group Health and seven other Vaccine Safety Datalink (VSD) centers across the country, e-published on January 14 in Pediatrics.

"These local reactions are the most common side effect of vaccinations," said study leader Lisa A. Jackson, MD, MPH, a senior investigator at Group Health Research Institute. "But we have known relatively little about how to prevent them." Local reactions go away after a day or two, but they can be painful, and the associated redness and swelling can concern parents. This study focused on "medically attended" local reactions: ones that resulted in a visit to a doctor, nurse, or emergency room. Ideally, medically attended local reactions would happen less often than the current nearly one in 100 vaccinated children.

"Our findings support current recommendations to give intramuscular vaccinations in the thigh for children younger than 3 years," Dr. Jackson said. Since 2011, the U.S. Advisory Committee on Immunization Practices (ACIP) has recommended that intramuscular vaccinations be given to toddlers aged 12 to 35 months preferably in the thigh muscle (or in the deltoid muscle of the arm only if it's big enough)and to children age 3 years older in the deltoid muscle of the arm. But in practice, health care providers tend to vary in their choice of vaccine injection sites for children; and parents can influence that decision.

The research team also tracked local reactions in children age 3 to 6 years and from intramuscular vaccines other than DTaP, including inactivated influenza and hepatitis A. But they found no statistically significant differences between vaccinating in the thigh and arm in the older age group or for the other intramuscular vaccines.

Previous evaluations of local reactions after the fifth DTaP vaccine in children age 4 to 6 years found that vaccination in the thigh was linked to a lower risk of local reactions than was vaccination in the arm. Dr. Jackson also led an earlier study that showed that neither ibuprofen (Advil) nor acetaminophen (Tylenol) help prevent local reactions after that vaccine.

The current research followed children age 1 to 6 years who received intramuscular vaccines from 2002 to 2009 at the eight VSD sites: Group Health; Harvard Pilgrim Health Care in Boston; HealthPartners in Minneapolis; Marshfield Clinic in Wisconsin; Kaiser Permanente Colorado in Denver; Kaiser Permanente Northwest in Portland; Kaiser Permanente Northern California in Oakland; and Kaiser Permanente Southern California in Los Angeles. The VSD project is a collaborative effort between the Centers for Disease Control and Prevention (CDC)'s Immunization Safety Office and 10 managed care organizations, including these eight (whose research institutes also happen to be members of the HMO Research Network).


Contact: Rebecca Hughes
Group Health Research Institute

Related medicine news :

1. Can breast cancer cells reaction to cancer drugs be predicted?
2. Reactions to everyday stressors predict future health
3. Chronic Pain May Depend on Emotional Reaction to Injury
4. Rate of severe reactions higher than thought in young children with food allergies
5. Study identifies causes for high rates of allergic reactions in children with food allergies
6. Genes May Influence Reactions to Painkillers
7. Reactions to HIV drug have autoimmune cause, reports AIDS journal
8. Blue Door Pharma and Global Energy Markets Strike Global Export Agreement for Meningitis Vaccine and Pharmaceuticals
9. Vaccine schedule safety: IOM Report to release Jan. 16
10. For One Woman, HPV Vaccine Was a No-Brainer
11. Boys in Australia to Receive the HPV Vaccine to Prevent Genital Warts; VyGone Introduced Ultimate Genital Warts Treatment in the US.
Post Your Comments:
Related Image:
Less reaction to DTaP vaccine given in kids' thighs than arms
(Date:11/26/2015)... Karnataka (PRWEB) , ... November ... ... innovative online platform for mental health and wellness consultation, has collaborated with ... to holistically address their reader’s queries on topics on mental and emotional ...
(Date:11/25/2015)... ... November 25, 2015 , ... As part of a global ... attracts volunteers together who want to combine talents and resources to help create ... the process. The non-profit launched its first major fundraiser on November 6, 2015 ...
(Date:11/25/2015)... Omaha, Neb. (PRWEB) , ... November 25, 2015 ... ... nurse staffing companies, has been recognized once again for its stellar workplace culture ... Places to Work.” , Medical Solutions’ Cincinnati office was named a ...
(Date:11/25/2015)... ... November 26, 2015 , ... Ministers, senior ... (EU), ANDI Pan African Centres of Excellence, and public R&D institutions, civil societies ... the opening of the 5th African Network for Drugs and Diagnostics Innovation, ANDI, ...
(Date:11/25/2015)... ... November 25, 2015 , ... According to an article published ... and more widely heralded as a breakthrough for performing hernia repairs. The article explains ... laparoscopic surgery is that it can greatly reduce the pain that a patient might ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , November 25, 2015 ... of self-monitoring blood glucose devices was valued at $11,171.1 ... with a CAGR of 5.7% during 2015 - 2022. ... population and increasing prevalence of diabetes. In addition, the ... care is also contributing to the growth of the ...
(Date:11/25/2015)... , November 25, 2015 Developmental, commercial, ... role in boosting the profitability of pharmaceutical products, ... commercial, and regulatory/legal strategies all play a ... says GBI Research . --> ... play a key role in boosting the profitability of pharmaceutical products, ...
(Date:11/25/2015)... 25, 2015 --> ... eine Lizenz für das Patent über eine neue Hepatitis-B-Behandlung, ... ENS-Lyon innehaben, an Enyo Pharma vergeben haben. ... Leben gerufenen und von Edelris gemeinsam mit seinen Partnern ... Behandlungsziel für HBV identifiziert, und es wurden neue Inhaltsstoffe ...
Breaking Medicine Technology: