Navigation Links
Less reaction to DTaP vaccine given in kids' thighs than arms
Date:1/13/2013

SEATTLEChildren age 12 to 35 months who receive DTaP vaccine in their thigh muscle rather than their arm are around half as likely to be brought in for medical attention for an injection-site reaction. So says a new study of 1.4 million children at Group Health and seven other Vaccine Safety Datalink (VSD) centers across the country, e-published on January 14 in Pediatrics.

"These local reactions are the most common side effect of vaccinations," said study leader Lisa A. Jackson, MD, MPH, a senior investigator at Group Health Research Institute. "But we have known relatively little about how to prevent them." Local reactions go away after a day or two, but they can be painful, and the associated redness and swelling can concern parents. This study focused on "medically attended" local reactions: ones that resulted in a visit to a doctor, nurse, or emergency room. Ideally, medically attended local reactions would happen less often than the current nearly one in 100 vaccinated children.

"Our findings support current recommendations to give intramuscular vaccinations in the thigh for children younger than 3 years," Dr. Jackson said. Since 2011, the U.S. Advisory Committee on Immunization Practices (ACIP) has recommended that intramuscular vaccinations be given to toddlers aged 12 to 35 months preferably in the thigh muscle (or in the deltoid muscle of the arm only if it's big enough)and to children age 3 years older in the deltoid muscle of the arm. But in practice, health care providers tend to vary in their choice of vaccine injection sites for children; and parents can influence that decision.

The research team also tracked local reactions in children age 3 to 6 years and from intramuscular vaccines other than DTaP, including inactivated influenza and hepatitis A. But they found no statistically significant differences between vaccinating in the thigh and arm in the older age group or for the other intramuscular vaccines.

Previous evaluations of local reactions after the fifth DTaP vaccine in children age 4 to 6 years found that vaccination in the thigh was linked to a lower risk of local reactions than was vaccination in the arm. Dr. Jackson also led an earlier study that showed that neither ibuprofen (Advil) nor acetaminophen (Tylenol) help prevent local reactions after that vaccine.

The current research followed children age 1 to 6 years who received intramuscular vaccines from 2002 to 2009 at the eight VSD sites: Group Health; Harvard Pilgrim Health Care in Boston; HealthPartners in Minneapolis; Marshfield Clinic in Wisconsin; Kaiser Permanente Colorado in Denver; Kaiser Permanente Northwest in Portland; Kaiser Permanente Northern California in Oakland; and Kaiser Permanente Southern California in Los Angeles. The VSD project is a collaborative effort between the Centers for Disease Control and Prevention (CDC)'s Immunization Safety Office and 10 managed care organizations, including these eight (whose research institutes also happen to be members of the HMO Research Network).


'/>"/>

Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute
Source:Eurekalert  

Related medicine news :

1. Can breast cancer cells reaction to cancer drugs be predicted?
2. Reactions to everyday stressors predict future health
3. Chronic Pain May Depend on Emotional Reaction to Injury
4. Rate of severe reactions higher than thought in young children with food allergies
5. Study identifies causes for high rates of allergic reactions in children with food allergies
6. Genes May Influence Reactions to Painkillers
7. Reactions to HIV drug have autoimmune cause, reports AIDS journal
8. Blue Door Pharma and Global Energy Markets Strike Global Export Agreement for Meningitis Vaccine and Pharmaceuticals
9. Vaccine schedule safety: IOM Report to release Jan. 16
10. For One Woman, HPV Vaccine Was a No-Brainer
11. Boys in Australia to Receive the HPV Vaccine to Prevent Genital Warts; VyGone Introduced Ultimate Genital Warts Treatment in the US.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Less reaction to DTaP vaccine given in kids' thighs than arms
(Date:7/21/2017)... Pass, OR (PRWEB) , ... July 21, 2017 ... ... in recent weeks Nature’s Tears® EyeMist®, the signature product of her research center ... country with the world’s largest population and the greatest number of sufferers of ...
(Date:7/21/2017)... TORONTO, ONTARIO, CANADA (PRWEB) , ... July 21, ... ... with over 80% follow-up at 10 years, researchers from the Multicenter Orthopaedics Outcome ... knee-related quality of life a decade after surgery, though activity levels decline over ...
(Date:7/21/2017)... ... 21, 2017 , ... How physicians and athletic trainers assess ... researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s ... the patterns of change in concussion symptom presentation, diagnostic tools used and length ...
(Date:7/20/2017)... ... , ... ChenMed , a leading provider of value-based care for seniors, ... as Richmond Chief Medical Officer. Dr. McCarter, formerly Associate Professor of Family Medicine ... Ambulatory Services for the UVA Health System, brings 30 years of highly relevant experience ...
(Date:7/20/2017)... July 20, 2017 (PRWEB) , ... ... ... Technologies, a global provider of enterprise-grade IT operations analytics and application performance ... of one of world’s largest healthcare services providers. , According to Peter ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... , July 10, 2017  BDI Group ... and patient support services organization serving specialty pharmacies, ... the launch of four significant, value-added member programs ... insights, better manage reimbursement and improve access and ... factor therapies. ...
(Date:7/6/2017)... July 6, 2017 ThriveRx, the nutrition division of Diplomat Specialty ... to thrive on nutrition support. To celebrate its anniversary, ThriveRx ... has a fresh new look with improved organization to create the best ... ... "We,ve made ...
(Date:7/5/2017)... of over 2,000 employees and a leader in environmental and life science testing, ... position as the top American owned and operated environmental testing firm in ... ... The ... , enhances Pace Analytical,s capability as an innovative full service provider in the ...
Breaking Medicine Technology: