Navigation Links
Less invasive methods may provide accurate means to determine lung cancer stage
Date:2/5/2008

An evaluation of several endoscopic biopsy methods suggests that a minimally invasive approach may accurately determine the stage of suspected lung cancer, according to a study in the February 6 issue of JAMA.

Lung cancer is the most common cancer-related cause of death in the United States. Determining the stage of the disease is a critical factor regarding therapy and prognosis, according to background information in the article.

Noninvasive staging with chest computed tomography (CT) or positron emission tomography (PET) is associated with high rates of false-positive and false-negative results, respectively. The American College of Chest Physicians recommends invasive staging with tissue confirmation of suspected metastatic mediastinal [center part of the thoracic cavity] lymph nodes. Mediastinoscopy or thoracoscopy [a surgical procedure that requires incisions] has been the diagnostic standard, but less invasive methods have emerged as potential alternatives, the authors write.

Such methods include blind transbronchial needle aspiration (TBNA), endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and, more recently, endobronchial ultrasound-guided fine-needle aspiration (EBUS-FNA).

Michael B. Wallace, M.D., M.P.H., of Mayo Clinic, Jacksonville, Fla., and colleagues compared the diagnostic accuracy of these three methods (and their combinations). Among 138 patients with suspected lung cancer who met all study criteria, 42 (30 percent) had malignant lymph nodes.

The researchers found that EBUS-FNA had higher sensitivity than TBNA (69 percent vs. 36 percent), detecting 29 (vs. 15) of the 42 malignant lymph nodes. EUS plus EBUS had higher estimated sensitivity (93 percent [39/42]) than any of the other methods. Compared with either EUS-FNA or EBUS-FNA alone, the combination identified 10 more malignant lymph nodes, with sensitivity estimated to be 24 percent higher than either approach alone.


'/>"/>

Contact: Paul Scotti
904-953-0199
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers find less invasive, highly accurate methods
2. Noninvasive ways to assess liver disease
3. Minimally Invasive Surgery Fixes Aneurysms
4. Z-shaped incision enhances minimally invasive surgery
5. Z-shaped incision enhances minimally-invasive surgery
6. Xeloda(R), Taxotere(R) and Herceptin(R) Combination Study Suggests Clinical Benefit in Invasive Breast Cancer with Shortened Treatment Cycle
7. Awake the Movie Highlights the Need for Goldilocks Anesthesia, Says Dr. Barry L. Friedberg, Developer of Bispectral Index (BIS) Monitored Propofol Ketamine Sedation, Now Trademarked as Minimally Invasive Anesthesia (MIA)(R)
8. Biomarkers predict risk for invasive breast cancer years before the tumor develops
9. AUA releases new guidelines on non-muscle invasive bladder cancer
10. Non-Invasive Fat-Melting Procedures - Hype or Reality?
11. ArthroCare Releases New SpineWand(R) for Less Invasive Spinal Surgeries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... CT (PRWEB) , ... August 01, 2015 , ... On March 19, 2015 Phil Valentine ... mile trek of the Appalachian Trail by stepping off Springer Mountain and heading ... , On July 26th Phil reached Connecticut and was greeted by friends and family. ...
(Date:7/31/2015)... CA (PRWEB) , ... August 01, 2015 , ... Super Bowl 50 will ... National Football League’s biggest day each year is the Super Bowl. In the two weeks ... takes place from the host venue. The 2016 Super Bowl game will mark the 50th ...
(Date:7/31/2015)... ... ... The 2nd annual Ride to Fight On will start and end near the ... to Fight On is a cycling fundraiser that benefits the West Cancer Center, a ... University of Tennessee Health Science Center. A health and wellness festival featuring food, music, ...
(Date:7/31/2015)... ... July 31, 2015 , ... Coco Libre announced today that their flagship ... at the 2015 Vans US Open of Surfing, July 25 through August 2 in ... added sugar” on the market, is a natural choice given the Open’s commitment to ...
(Date:7/31/2015)... ... , ... Well-known for its unique pastries and delicious confections, Pastry Palace, a ... making life just a little bit sweeter for newlyweds. A family-owned business, the Pastry ... one. , The bakery provides a full line of custom wedding cakes. Brides can ...
Breaking Medicine News(10 mins):Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2
... Inc. (Nasdaq: OSTE ), a leader in ... announced today that the Company,s fourth quarter and full ... released Wednesday, March 4, 2009. The management team of ... Thursday, March 5, 2009, at 9:00 a.m. (EST) to ...
... March 2 At Aurora Health Care , finding ... businesses that rely on the health care provider for health ... well-being of its own employees, and that commitment recently was ... its local affiliate the Wellness Council of Wisconsin, presented its ...
... March 2 Speaker Nancy Pelosi released the ... Kathleen Sebelius as Secretary of the Department of Health ... bipartisan leader who has worked to expand health care ... prescription drugs. "Governor Sebelius, deep understanding of health care ...
... March 2 Nitinol Devices & Components, Inc. ... novel medical device anchoring technology from Phase One ... This anchoring technology integrates the superelastic material properties ... provide secure fixation and removability for minimally invasive ...
... cites association on GMPs and adverse event reportingWASHINGTON, ... the U.S. Government Accountability Office (GAO) of a ... supplements, the Natural Products Association (NPA) released the ... Seckman."The Natural Products Association appreciates having the opportunity ...
... 2 /PRNewswire-Asia-FirstCall/ -- China Nepstar,Chain Drugstore Ltd. (NYSE: ... drugstore chain in China based on the number of ... the fourth quarter and,fiscal year 2008 financial results ended ... 16, 2009. , The Company ...
Cached Medicine News:Health News:Aurora Wins Gold Well Workplace Award for Commitment to Employee Health and Well-Being 2Health News:NDC Completes Acquisition of Phase One Medical(R) Anchoring Technology 2Health News:Natural Products Association Comments on New GAO Report on Regulation of Dietary Supplements 2Health News:China Nepstar Chain Drugstore to Announce Fourth Quarter and Fiscal 2008 Financial Results on March 16 2
(Date:7/30/2015)... PARK, N.J. , July 30, 2015  Unichem ... voluntarily recalling one lot of Hydrochlorothiazide tablets 25 mg ... been initiated as a precautionary measure due to the ... of the product. The risk associated ... Hydrochlorothiazide tablet is the increased probability of experiencing Clopidogrel,s ...
(Date:7/30/2015)... July 30, 2015 PTC Therapeutics, Inc. (NASDAQ: ... reported financial results for the second quarter ending June ... many fronts across the organization.  We are excited to ... dystrophy clinical trial ever conducted with topline results expected ... Chief Executive Officer, PTC Therapeutics, Inc. "Translarna is now ...
(Date:7/30/2015)... , July 30, 2015  Cleveland Clinic President ... 2015 keynote address last month that industry is compelled ... order to gain the efficiencies—and develop the transformational innovations ... Dr. Barsoum,s comments were preceded by Doug Kohrs ... and OMTEC moderator, who stressed that industry must add ...
Breaking Medicine Technology:Unichem Pharmaceuticals (USA), Inc. Issues a Voluntary Nationwide Recall of Hydrochlorothiazide Tablets Due to the Potential Presence of Foreign Tablets 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 4PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 5PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 6PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 7PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 8PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 9PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 10Orthopaedic Surgery Reimbursement Shifts to Episode of Care 2
... MUNDELEIN, Ill. , July 1 ... and information systems developer, today announces executive changes in ...  John Kershaw, President & CEO, Sysmex America Inc. has ... Secretary; Judy Bosko as Vice President of ...
... SCHAUMBURG, Ill. , July 1 ... today announced that the U.S. Food and Drug Administration ... sodium injection, USP. Heparin is a vital anticoagulant, preventing ... within the blood, routinely used in surgical and dialysis ...
Cached Medicine Technology:Sysmex America Announces Executive Leadership Changes 2FDA Approves Sagent Pharmaceuticals' Heparin Sodium Injection, USP 2FDA Approves Sagent Pharmaceuticals' Heparin Sodium Injection, USP 3FDA Approves Sagent Pharmaceuticals' Heparin Sodium Injection, USP 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: