Navigation Links
Less blood needed post-surgery, says NEJM study
Date:12/15/2011

of physicians follow a "restrictive" approach using a lower threshold or symptoms of anemia. In addition, some physicians choose to give blood transfusions to patients with higher blood counts if they are elderly or have cardiovascular disease. Normally, people have blood counts above 12 g/dL.

The study followed 2,016 patients aged 50 years or older with a history of or risk factors for cardiovascular disease, who underwent surgery for hip fracture. They were randomized into two groups: one that received a transfusion when their hemoglobin level fell below 10 g/dL (liberal group) and another that received a transfusion when they had symptoms of anemia, or at a physician's discretion if their hemoglobin was below 8 g/dL (restrictive group). The two groups had similar results for a large array of clinical outcomes, including risk for death within 60 days; functional recovery; risk for heart attack, infection, and falls; and symptoms such as fatigue. Median age was 82 years.

The difference in blood use was striking. Patients in the restrictive group received 65 percent fewer units of blood than the liberal group, and 58.5 percent of patients in the restrictive group did not receive any blood transfusion.

"As the medical community further embraces a restrictive approach to post-surgery blood transfusion, it's important that physicians carefully evaluate patients for symptoms of anemia, and not just rely on hemoglobin levels. The patient's body will often tell us when it needs blood," says Dr. Macaulay.

The FOCUS trial confirms findings of the 1999 Transfusion Requirements in Critical Care Investigators (TRICC) trial, which found that outcomes of a 7 g/dL transfusion threshold and a 10 g/dL threshold were similar for patients in an intensive care setting. FOCUS did not find evidence of increased rates of death, heart attack, or congestive heart failure in its liberal group, despite anecdotal evidence.


'/>"/>
Contact: Gloria Chin
glc9010@nyp.org
212-305-5587
New York- Presbyterian Hospital/Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Team designs a bandage that spurs, guides blood vessel growth
2. Blood test might predict how well a depressed patient responds to antidepressants
3. Low Iron Levels May Increase Blood Clot Risk
4. Key genetic error found in family of blood cancers
5. University of Maryland finds restricting post-surgery blood transfusion is safe for some hip patients
6. Study Finds Fewer Blood Transfusions Needed After Hip Surgeries
7. Cancer Outpatients at Greater Risk for Blood Clots
8. Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient
9. Massive DNA search uncovers new mutations driving blood cancer
10. Researchers use new finding to clear bloodstream malaria infection in mice
11. Blood pressure monitoring: Room for improvement
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... (PRWEB) , ... July 28, 2015 , ... Almost a ... plans to offer behavioral health counseling for persons who are obese and those who ... was less clear. , That mandate will affect any commercial health plan with a ...
(Date:7/27/2015)... ... , ... Combination Product GMP Compliance:, Understanding FDA’s New Streamline Approach, **FDAnews Webinar**, ... http://www.fdanews.com/comboproductgmpcompliance , Manufacturing a drug or device is hard enough — even for ... a hurry. In a 46-page draft guidance released in January, FDA clarified a 2013 ...
(Date:7/27/2015)... Falls Church, VA (PRWEB) , ... July 28, ... ... , Understanding Advanced Critical Thinking Skills and Innovative Techniques to Improve the Quality ... Raleigh, NC, http://www.fdanews.com/capapc , Inadequate investigations and CAPAs have been the ...
(Date:7/27/2015)... ... July 28, 2015 , ... ... Team) as the sports medicine provider for the entire school district including Anderson ... to ACHS Athletic Director Rick Sallee, “Student safety and well-being are a top ...
(Date:7/27/2015)... , ... July 27, 2015 , ... ... diabetes, are associated with smaller regional brain volumes that may be early indicators ... journal Radiology. , “We already know that vascular risk factors damage the brain ...
Breaking Medicine News(10 mins):Health News:How Digital Therapeutics Can Help Payers Out of Regulatory Fix 2Health News:How Digital Therapeutics Can Help Payers Out of Regulatory Fix 3Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 2Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 3Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 4Health News:FDAnews Announces: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 16-17, 2015, Raleigh, NC 2Health News:FDAnews Announces: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 16-17, 2015, Raleigh, NC 3Health News:FDAnews Announces: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 16-17, 2015, Raleigh, NC 4Health News:KORT Physical Therapy Named Sports Medicine Provider for Anderson County School System 2Health News:KORT Physical Therapy Named Sports Medicine Provider for Anderson County School System 3Health News:RSNA: Specific Cardiovascular Risk Factors May Predict Alzheimer’s Disease 2Health News:RSNA: Specific Cardiovascular Risk Factors May Predict Alzheimer’s Disease 3
... from NIDCR have created an animal model that ... II and dentin dysplasia. Dr. Ashok Kulkarni and ... amounts of TGF-b1 (transforming growth factor beta-1) in ... apparent defects, but at two weeks their teeth ...
... researchers people who sleep for more or less than seven ... over one million adults conducted over a six year time ... hours sleep a night might need modifying. Looking at the ... expectancy, researchers at the University of Texas, and colleagues, find ...
... an exclusively Western problem. Researchers say weight problems ... in developing nations, particularly children. Until recently, famine ... to the health of poor people in developing ... processing and even leisure time in developing countries ...
... kidney cancer in the UK has risen by 68 per cent ... a year. Research in UK says that 5,700 people each year ... lowest in Europe.// The disease accounts for an estimated 95,000 worldwide ... ,According to Dr Nick James, a consultant at the Queen Elizabeth ...
... conduct tests for any Indian doctor having graduated abroad avid ... higher standards amongst doctors, the government has made it compulsory ... today. , The new regulations, ... students who want to enrol in MBBS course abroad will ...
... men tend to die younger than married ones. Psychiatrists ... health by giving them emotional ward.// ,Researchers in ... heart disease and stroke were higher in unmarried men ... in death rates between married and unmarried women. ...
Cached Medicine News:Health News:Heriditary dental disorders 2
(Date:7/27/2015)... WESTLAKE VILLAGE, Calif. , July 27, 2015 /PRNewswire/ ... Biopharmaceuticals, Inc. (NASDAQ: KYTH ) today announced that ... termination of the waiting period under the Hart-Scott-Rodino Antitrust ... Allergan,s pending acquisition of KYTHERA.  Logo - ... 2015, each of Allergan and KYTHERA filed a Pre-Merger ...
(Date:7/27/2015)... July 27, 2015   Mallinckrodt plc ... company, announced today that it has entered into ... its global contrast media and delivery systems (CMDS) ... transaction valued at approximately $270 million.   ... is consistent with the company,s stated plan to ...
(Date:7/27/2015)... , July 27, 2015  EnzymeBioSystems (OTC BB: ... batch has been completed. Amooranin is the Company,s lead ... use of methyl amooranin in the prevention of breast ... this preclinical batch of methyl amooranin has been completed," ... went on to say, "This batch will allow us ...
Breaking Medicine Technology:Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 2Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 3Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 4Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 5Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 6Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 7Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 8Allergan and KYTHERA Announce Early Termination of Hart-Scott-Rodino Waiting Period for Allergan's Pending Acquisition of KYTHERA 9Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 2Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 3Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 4Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 5Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 6Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 7Amooranin Preclinical Sample Batch Completed 2
... Jan. 13, 2011 Baylor Health Care System is ... quality of patient care in North Texas through the ... health care system.  It is one of thousands of ... with the U.S. Department of Health and Human Services ...
... 13, 2011 Dendreon Corporation (Nasdaq: DNDN ) ... other conditions, $500 million aggregate principal amount of convertible senior ... registered under the Securities Act of 1933, as amended (the ... of Dendreon,s common stock (the "Common Stock") or a combination ...
Cached Medicine Technology:Baylor Health Care System Registers its Commitment to Achieve Meaningful Use of the Electronic Health Record 2Dendreon Announces Offering of $500 Million Convertible Senior Notes Due 2016 2Dendreon Announces Offering of $500 Million Convertible Senior Notes Due 2016 3Dendreon Announces Offering of $500 Million Convertible Senior Notes Due 2016 4
... The Alaris System integrates drug ... practice guidelines,into a single, modular platform. ... or remove modules as you,need them, ... the bedside,to a minimum while managing ...
... Eraser instruments have been designed to ... right tool for situations requiring precise ... of 25 gauge intraocular, bipolar, diathermy ... of target tissues for fine-tip hemostasis ...
... steps any hospital or health system can ... most effective tools available for physicians and ... documentation and electronic medical record (EMR) system, ... goal. In fact, its the most reliable ...
... These specialty Eraser instruments have ... surgeon with the right tool for ... introduced a series of 25 gauge ... provide discrete treatment of target tissues ...
Medicine Products: