Navigation Links
Less Invasive Lung Cancer Staging Looks Promising
Date:11/23/2010

By Steven Reinberg
HealthDay Reporter

TUESDAY, Nov. 23 (HealthDay News) -- A less invasive method for finding out whether lung cancer has spread to the lymph nodes could prevent many unnecessary operations, a new study suggests.

This process, called staging, is usually done via a major operation called a thoracotomy. If the cancer is confined to the lung, then the operation can remove the cancer. However, if the cancer has spread, then it is an unnecessary procedure, which only serves to increase the patient's discomfort.

The much less invasive procedure, called an endosonography, combines ultrasound of internal organs with the use of a fiberoptic endoscope, which can also biopsy the lymph nodes.

"We found that a new strategy using ultrasound is better to check for metastasis than traditional surgical staging," said lead researcher Dr. Jouke T. Annema, director of Endosonography for Pulmonary Medicine at Leiden University Medical Center in the Netherlands.

Staging the cancer is important, because the type of treatment depends on whether the cancer has spread beyond the lung or not.

If the lymph nodes are cancer-free, the patients will be treated by removing the cancer from the lung, Annema said. If there is cancer in the lymph nodes, then the treatment is completely different, with chemotherapy and radiation, he explained.

The current standard of thoracotomy to stage cancer results in many patients not receiving the best treatment, Annema said. Using endosonography will make it possible to reduce unnecessary lung operations by half, he added.

The findings are published in the Nov. 24 issue of the Journal of the American Medical Association.

The study follows on the heels of a major U.S. government report that found that annual screening for lung cancer with low-dose CT scans cut death rates in older, current or former heavy smokers by 20 percent. The scans also reduced death rates for any cause by 7 percent.

Given that lung cancer is the nation's leading cancer killer, this new study is another piece of good news.

For the current study, Annema and colleagues compared less invasive staging of lung cancer using endosonography, which combined transesophageal and endobronchial ultrasound, with surgery in 241 lung cancer patients.

These patients underwent either surgery or endosonography followed by surgery when no nodal metastases were found at endosonography.

Of the 241 patients, 118 had surgical staging and 123 endosonography. Of those who received endosonography, 65 also underwent surgery, the researchers noted.

Among the patients whose cancer had spread beyond the lung, 41 (35 percent) were identified by surgery, while 56 (46 percent) were spotted by endosonography and 62 (50 percent) were pinpointed after endosonography followed by surgery.

There were 21 unnecessary surgeries in the surgical group (18 percent), compared with nine (7 percent) in the endosonography group, Annema's team found.

In addition, there was no difference in the rate of complications between the groups, they note.

"We expect current guidelines will be changed," Annema said.

Commenting on the study, Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City, said that, "if this can be borne out in larger trials, going to thoracotomy to stage patients may not be necessary."

If you can spare someone with extensive disease a thoracotomy with the chances of complications and extensive healing time, treatment with chemotherapy and radiation can start much sooner, he said.

"If you do an unnecessary thoracotomy, you are really delaying treatment," Horovitz said. Before this new method could become standard care, doctors would need to be trained in the technique, he added.

Another expert agrees this new technique could be a better option than a thoracotomy for diagnosing the stage of lung cancer.

Dr. Otis W. Brawley, chief medical officer at the American Cancer Society, added that "to me it seems like a better way of staging patients prior to surgery."

The big advantage of this new technique is that it will spare patients with advanced lung cancer needless surgery, he said.

"This has the potential of becoming standard care," Brawley said. "I will predict that it will become standard in many of the cancer centers that specialize in lung cancer."

More information

For more information on lung cancer, visit the U.S. National Cancer Institute.

SOURCES: Jouke T. Annema, M.D., Ph.D., director, Endosonography for Pulmonary Medicine, Leiden University Medical Center, the Netherlands; . Len Horovitz, M.D., pulmonary specialist, Lenox Hill Hospital, New York City; Otis W. Brawley, M.D., chief medical officer, American Cancer Society; Nov. 24, 2010, Journal of the American Medical Association


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Noninvasive brain stimulation helps improve motor function in stroke patients
2. Soy Chemicals May Lower Risk for Invasive Breast Cancer
3. Noninvasive Test for Colon Cancer Shows Promise in Early Trial
4. Hormone therapy increases invasive breast cancer and mortality, WHI 11-year follow up finds
5. Invasive Dentistry May Raise Short-Term Heart, Stroke Risk
6. Non-invasive therapy significantly improves depression, UCLA researchers say
7. Less Invasive Biopsies Gain Favor
8. Non-Invasive Diagnosis of Inflammatory Bowel Disease Shows Promise
9. Prediction tool helps estimate local recurrence in patients with noninvasive breast cancer
10. Use of Less Invasive, Imaging-Guided Biopsies on the Rise
11. Use of less invasive, imaging-guided biopsies on the rise
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Less Invasive Lung Cancer Staging Looks Promising
(Date:8/22/2017)... ... ... “To Walk Away”: a captivating and romantic sequel to the romantic story ... is the creation of published author, Larry R. Sherman, a retired chemistry professor from ... religion, as well as four novels. , Though the book opens in 1947, ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Without Love’s Beauty ... neglect, and the struggles faced while hoping for a better life. “Without Love’s ... Judy Von Bernewitz, who spent 13 years working with deprived/neglected adolescents and almost ...
(Date:8/22/2017)... ... August 22, 2017 , ... “Glimpses Of Light”: is a ... “Glimpses Of Light” is the creation of published author, J.M. Shepherd, a writer, teacher, ... answers to life’s perplexing mysteries. , Shepherd shares, “Love is one of the least ...
(Date:8/22/2017)... ... August 22, 2017 , ... TopConsumerReviews.com recently gave a best-in-class ... Fatigue . , As the stress of modern life continually makes more demands on ... use of artificial stimulants can trap people in vicious high/low cycles and can also ...
(Date:8/22/2017)... Indiana (PRWEB) , ... August 22, 2017 , ... Although ... Fourth of July, many communities have begun providing weekend displays, and numerous households celebrate ... most humans, they can be downright terrifying for pets. , Kris Zambo, owner ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... 2017  AOTI Inc. announced today that its fully owned ... opened a New York City Office in Yonkers, New ... Topical Wound Oxygen (TWO 2 ) homecare therapy. This new East ... Health Care (ACHC) under the company,s DMEPOS accreditation for Home/Durable Medical ... Advanced Oxygen ...
(Date:8/10/2017)... Aug. 10, 2017  Physical Rehabilitation Network (PRN), acquired the ... Lakewood, Colorado . The reputable clinic will continue ... PT, DPT with his staff of four clinicians. Lipkin received ... and brings over 10 years of experience with a strong ... Belmar PT marks the 10th PRN clinic in and around the ...
(Date:8/7/2017)... 2017 Insightin Health, provider of data-driven ... engagement, announced the selection of Michael Wood ... effective as of February 2017. In this role, Wood ... for our clients. Wood brings with him more ... business analytics within the healthcare industry. Wood formerly ...
Breaking Medicine Technology: