Navigation Links
Leprosy Genes Identified
Date:12/16/2009

Scientists pinpoint seven that increase susceptibility to disease

WEDNESDAY, Dec. 16 (HealthDay News) -- Seven genes associated with increased susceptibility to leprosy have been identified by scientists in Singapore and China.

The researchers, who analyzed more than 10,000 DNA samples from leprosy patients and healthy people in China, said their discovery highlights the important role that the innate immune response plays in the development of leprosy.

"Though leprosy is not common, the discoveries have significant ramifications for chronic infectious disorders and for host-pathogen interactions in other more prevalent mycobacterial diseases such as tuberculosis," Dr. Edison Liu, executive director of the Genome Institute of Singapore, said in a news release from the institute.

"The discovery of these genes is a major breakthrough for research in leprosy and infectious diseases in general, and will be significant in the early diagnosis and development of new treatments," study co-leader Jianjun Liu, Human Genetics Group Leader at the institute, said in the release.

The study appears online Dec. 16 in the New England Journal of Medicine.

The genes are: CCDC122, C13orf31, NOD2, TNFSF15, HLA-DR, RIPK2 and LRRK2.

Leprosy is a chronic infectious disease caused by the bacterium Mycobacterium leprae. The disease, which mainly affects skin and peripheral nerves, is rare in developed countries, but remains a major public health problem in many developing countries. According to the World Health Organization, 254,525 new cases of leprosy were diagnosed in 2007.

In regions where leprosy is common, many people are exposed but only a few become infected and develop clinical signs of leprosy, which indicates that only certain people are susceptible to the disease.

More information

The U.S. National Library of Medicine has more about leprosy.



-- Robert Preidt



SOURCES: Agency for Science, Technology and Research, Singapore, news release, Dec. 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New York Community Trust Awards Grant of $100,000 to Infectious Disease Research Institute for Early Detection Leprosy Tests
2. Forgotten, but not gone: Leprosy still present in the US
3. Researchers identify new leprosy bacterium
4. Leprosy Lingers in the U.S.
5. Local Web Design Agency Launches Leprosy Charity Website for Women in Need
6. DNA of Jesus-era shrouded man in Jerusalem reveals earliest case of leprosy
7. Pathway links inflammation, angiogenesis and breast cancer
8. Traffic Fumes Plus Genes Boosts Kids Asthma Risk
9. New Database to Help Speed Search for Bipolar Disorder Genes
10. Is Perfect Pitch All in the Genes?
11. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2020)... , ... May 26, 2020 , ... ... coronavirus pandemic, medical centers across the United States are joining forces to start ... workers who have worked tirelessly to save lives. #FitForTheFrontLine is a national fitness ...
(Date:5/21/2020)... ... May 21, 2020 , ... Summit Medical , ... deliver over one million FDA-compliant face shields — designed, engineered and manufactured in ... critical need for personal protective equipment (PPE) for both front-line health care workers ...
(Date:5/21/2020)... ... May 21, 2020 , ... Friends of Lisa Campbell, announce that ... by Planned Parenthood Southeast Advocates (PPSEA). PPSEA educates and lobbies on ... the full range of reproductive health care. PPSEA educates and lobbies on behalf of ...
(Date:5/21/2020)... ... May 21, 2020 , ... Casenet® LLC today released ... supports care management and utilization management at health insurance plans. Developed over two ... provides significant usability and automation upgrades to all of its existing features, introduces ...
(Date:5/16/2020)... ... 15, 2020 , ... For patients who have gone to see Andy Gaertner, D.M.D , ... always had in place. After being allowed to re-open during the current pandemic, they have ... are as safe and comfortable as possible while going through their dental exams and treatments. ...
Breaking Medicine News(10 mins):
(Date:5/25/2020)... Calif. (PRWEB) , ... May 24, 2020 , ... ... Inc., the San Luis Obispo electricians, want the public to know what ... the nonprofit Electrical Safety Foundation International (ESFI) launches an education campaign to inform ...
(Date:5/21/2020)... N.Y. (PRWEB) , ... May 21, 2020 , ... ... Front-Line Medical Workers , Latham to help manufacture 25,000 polymer film gowns that ... world's largest manufacturer of inground residential swimming pools and accessories, is excited to ...
(Date:5/21/2020)... , ... May 21, 2020 , ... In today’s news ... wear masks; to touch or shake hands with others; to avoid restaurants, movie theaters, ... get comfortable with your Netflix, AppleTV+, YoutubeTV or Prime Video subscriptions. But as things ...
Breaking Medicine Technology: