Navigation Links
Leicester leads on heart attack genetic link discovery
Date:3/6/2011

The largest-ever study of its type into coronary heart disease, involving scientists from the University of Leicester, has uncovered 13 new genes that increase risk of heart attacks.

Professor Nilesh Samani, British Heart Foundation Professor of Cardiology at the University of Leicester, based at Glenfield Hospital, who co-led the international research programme, called CARDIoGRAM, said most of genes identified were not previously known to be involved in the development of coronary heart disease, opening of the possibility of developing new treatments for this common disease.

The study involved over 167 clinicians and scientists from UK, Europe, Iceland, USA and Canada and over 140,000 participants. The researchers assessed the genetic codes of people to search for variations in DNA that are more likely to be found in people with coronary heart disease.

Professor Samani said: "The most exciting thing about our study is that we have discovered several new genes not previously known to be involved in the development of coronary heart disease, which is the main cause of heart attacks. Understanding how these genes work, which is the next step, will vastly improve our knowledge of how the disease develops, and could ultimately help to develop new treatments."

Professor Samani added that the scale of the study showed the benefits of international collaboration in tackling major research questions of this type.

He said: "The study would not have been possible without the many patients right across Britain who participated in our British Heart Foundation Family Heart Study and others like them all round the world. This is a real tribute to their contribution."

Professor Peter Weissberg, Medical Director at the BHF, said: "As more and more large scale genetic studies are carried out we are beginning to identify genes that may play a significant, though small, role in the development of heart disease.

"Each new gene identified brings us a small step closer to understanding the biological mechanisms of cardiovascular disease development and potential new treatments. However, as the number of genes grows, it takes us further away from the likelihood that a simple genetic test will identify those most of risk of suffering a heart attack or a stroke."

The study is published in the leading journal, Nature Genetics.


'/>"/>

Contact: University of Leicester Press Office
pressoffice@le.ac.uk
44-116-252-3335
University of Leicester
Source:Eurekalert

Related medicine news :

1. New research at the University of Leicester links shoplifting to your personality
2. Learning Lab of Brentwood Leads Free ADHD Seminar
3. Human Dental Technology Leads to Breakthroughs for Pet Dental Health at Sergeants Pet Care Products, Inc.
4. TechCFO Enters Mid-Atlantic Market; Rick Rolandi Leads DC Metro Office
5. Home Health Agency Owner Pleads Guilty in Connection with Detroit Fraud Scheme
6. New DNA technique leads to a breakthrough in child cancer research
7. AGA leads the way in GI innovation
8. Arsenic exposure activates an oncogenic signaling pathway; leads to increased cancer risk
9. KV Pharmaceutical Subsidiary Pleads Guilty to Two Felonies Regarding Oversized Drugs
10. China's Forbidden City Leads Landmark Climate Action for Earth Hour
11. McMaster researcher leads development of promising drug for inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... February 05, 2016 , ... Francisco Canales, ... services in their Napa Valley office. The technique utilizes the body’s own healing ... Canales and Dr. Furnas, are part of only a select few cosmetic surgeons ...
(Date:2/5/2016)... ... ... US Sports Camps , official operators of Nike Yoga Camps, announces ... training. ChildLight Yoga Studio is centrally situated in the picturesque New England city of ... founder Lisa Flynn expresses her excitement, “We are thrilled to be partnering with US ...
(Date:2/5/2016)... ... February 05, 2016 , ... Boar’s Head Brand®, one of ... for this weekend’s Big Game. Take the stress out of your party preparation – ... guests happy at every stage of the game. , “The key to hosting a ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... CitiDent, announces that it is now welcoming orthodontist, Dr. Amanda Cheng, to ... a complete range of oral health care, including general dentistry, cosmetic treatments, periodontics, ...
(Date:2/5/2016)... ... February 05, 2016 , ... On June 9-10, Las ... continuing medical education (CME) event presented by the Association for Comprehensive Care in ... for ACCORD, whose mission is to provide education, tools, and resources to primary ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , February 5, 2016 Site ... Today, VoicePower Ltd - The Speech Recognition People, announced their latest ... to improve patient care, reduce turnaround times and to save the ... ,- VoicePower client since 2013 Challenge: --> ... --> - Six doctors ,- Wirral CCG ,- VoicePower ...
(Date:2/4/2016)... , Feb. 4, 2016  Edwards Lifesciences Corporation (NYSE: ... for structural heart disease and critical care monitoring, announced ... repurchase (ASR) agreement with Morgan Stanley & Co. LLC ... repurchase is part of the Company,s previously authorized program ... common stock.  --> ...
(Date:2/4/2016)... , Feb. 4, 2016  SciClone Pharmaceuticals, Inc. ... it has entered into a settlement agreement with ... fully resolving the SEC,s investigation into possible violations ... the terms of the settlement agreement, SciClone has ... including disgorgement, pre-judgment interest and a penalty.  This ...
Breaking Medicine Technology: