Navigation Links
Leicester leads on heart attack genetic link discovery
Date:3/6/2011

The largest-ever study of its type into coronary heart disease, involving scientists from the University of Leicester, has uncovered 13 new genes that increase risk of heart attacks.

Professor Nilesh Samani, British Heart Foundation Professor of Cardiology at the University of Leicester, based at Glenfield Hospital, who co-led the international research programme, called CARDIoGRAM, said most of genes identified were not previously known to be involved in the development of coronary heart disease, opening of the possibility of developing new treatments for this common disease.

The study involved over 167 clinicians and scientists from UK, Europe, Iceland, USA and Canada and over 140,000 participants. The researchers assessed the genetic codes of people to search for variations in DNA that are more likely to be found in people with coronary heart disease.

Professor Samani said: "The most exciting thing about our study is that we have discovered several new genes not previously known to be involved in the development of coronary heart disease, which is the main cause of heart attacks. Understanding how these genes work, which is the next step, will vastly improve our knowledge of how the disease develops, and could ultimately help to develop new treatments."

Professor Samani added that the scale of the study showed the benefits of international collaboration in tackling major research questions of this type.

He said: "The study would not have been possible without the many patients right across Britain who participated in our British Heart Foundation Family Heart Study and others like them all round the world. This is a real tribute to their contribution."

Professor Peter Weissberg, Medical Director at the BHF, said: "As more and more large scale genetic studies are carried out we are beginning to identify genes that may play a significant, though small, role in the development of heart disease.

"Each new gene identified brings us a small step closer to understanding the biological mechanisms of cardiovascular disease development and potential new treatments. However, as the number of genes grows, it takes us further away from the likelihood that a simple genetic test will identify those most of risk of suffering a heart attack or a stroke."

The study is published in the leading journal, Nature Genetics.


'/>"/>

Contact: University of Leicester Press Office
pressoffice@le.ac.uk
44-116-252-3335
University of Leicester
Source:Eurekalert

Related medicine news :

1. New research at the University of Leicester links shoplifting to your personality
2. Learning Lab of Brentwood Leads Free ADHD Seminar
3. Human Dental Technology Leads to Breakthroughs for Pet Dental Health at Sergeants Pet Care Products, Inc.
4. TechCFO Enters Mid-Atlantic Market; Rick Rolandi Leads DC Metro Office
5. Home Health Agency Owner Pleads Guilty in Connection with Detroit Fraud Scheme
6. New DNA technique leads to a breakthrough in child cancer research
7. AGA leads the way in GI innovation
8. Arsenic exposure activates an oncogenic signaling pathway; leads to increased cancer risk
9. KV Pharmaceutical Subsidiary Pleads Guilty to Two Felonies Regarding Oversized Drugs
10. China's Forbidden City Leads Landmark Climate Action for Earth Hour
11. McMaster researcher leads development of promising drug for inflammation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... “Tomorrow Trump Goes To Washington”: ... greatness back to the presidency and to America. “Tomorrow Trump Goes To Washington” is ... much as she can for this country. , Nancy attributes her patriotic nature to ...
(Date:12/7/2016)... ... 2016 , ... “Fred Rides a Train” allows readers to tag along on ... Rides a Train” is the creation of published author, Janet Morrison, who has been ... Michigan. The "Fred, the Dog" series is her first attempt at writing for children. ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... annual Business Architecture Innovation Summit in Reston, VA on March 21-22, 2017. This ... share a range of experiences from a cross-section of industries such as financial ...
(Date:12/7/2016)... ... December 07, 2016 , ... NuevaCare, a leading home ... is proud to announce new city-specific pages as part of its ambitious website relaunch. ... they often look, first, for local agencies serving their city. The new site has ...
(Date:12/6/2016)... ... 06, 2016 , ... People with Parkinson’s disease and cognitive ... type of MRI, according to a study appearing online in the journal Radiology. ... characterized by tremors or trembling and stiffness in the limbs, impaired balance and ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7, 2016  Lannett Company, Inc. (NYSE: LCI ) ... Markets 2016 Prescription for Success Healthcare Conference on December 14, 2016 ... New York City . In addition, the ... Guggenheim Securities 4 th Annual Boston Healthcare Conference taking place ... ...
(Date:12/6/2016)... , Dec. 6, 2016 Radioisotopes are ... Radioisotopes are produced either by using nuclear research reactor ... the form of alpha, beta or gamma when changed ... are used in Nuclear medicine, specifically in medical diagnostics. ... diagnostic information about a human body,s functioning. Radiotherapy is ...
(Date:12/6/2016)... Dec. 6, 2016 Human Vaccines Market: ... region wise and country wise analysis of the ... manufacturers of human vaccines products, raw material suppliers, ... enter the market. The report provides qualitative ... market. Qualitative analysis comprises market dynamics, trends, product ...
Breaking Medicine Technology: