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Leibniz Prize 2012 to honor 11 outstanding researchers
Date:12/14/2011

n of various immune-system cells to build an immune response and the pathogenesis of inflammation, to the development of intestinal paralysis after abdominal surgery and of special forms of nephritis. A key motivation behind Kurth's research is always the indirect application of findings in a therapy setting. Several of his works have refuted what used to be universally accepted assumptions in immunology. Christian Kurts was a Heisenberg fellow of the DFG, which also funded his two-year research stay in Australia. In Bonn since 2003, Kurt is now director of the Institute of Experimental Immunology. Outstanding both as a researcher and a clinician, he also exerts a great attraction as an academic teacher on clinically oriented young scientists.

Prof. Dr. Matthias Mann (52), Biochemistry, Max Planck Institute of Biochemistry, Martinsried

Without Matthias Mann's work that is now being honoured with the Leibniz Prize, modern biology would basically be impossible. An exceptionally resourceful and successful developer and user of methods, this biochemist has shaped large-scale proteomics and thus the detection of all proteins in biological systems. His greatest achievement is the application of a mass spectrometry technique, originally used in physics, to problems of molecular biology, which he pursued in various ways. His early contributions to the development of electrospray ionisation paved the way for biological mass spectrometry in general. Just as important are the software algorithms developed by Mann that enable the analysis of mass spectrometry data using sequence databases. These and other approaches, such as the SILAC method for the direct comparison of thousands of proteins, are now used in laboratories worldwide. Working with renowned research teams, Mann has also used these techniques himself: In 2008, for example, he was able to perform the first complete proteome analysis of an organism using baker's yeast as a model. His next big
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Contact: Marco Finetti
marco.finetti@dfg.de
49-228-885-2230
Deutsche Forschungsgemeinschaft
Source:Eurekalert

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