Navigation Links
Least Aggressive Breast Cancer Still Poses Long-Term Risk, Study Finds
Date:9/18/2012

TUESDAY, Sept. 18 (HealthDay News) -- The most common and least aggressive form of breast cancer still poses a risk of death more than 10 years after a woman is diagnosed with the disease, according to a new long-term study.

The findings could affect how doctors treat women with this type of breast cancer, the researchers said.

Their 21-year study of nearly 1,000 women in California found that molecular subtypes of breast cancer were important independent predictors of death from breast cancer. In particular, women with luminal A tumors (a subtype of breast cancer generally believed to have the best prognosis) were still at risk for death from the cancer more than 10 years after their diagnosis.

The researchers at Kaiser Permanente Southern California also found that women with HER2-enriched and luminal B tumors were about twice as likely to die from breast cancer than those with luminal A tumors. That result is consistent with previous research.

"The findings of this study indicate that it is important to consider breast cancer molecular subtypes in determining the optimal treatment for women with breast cancer," study author Reina Haque said in a Kaiser news release. "Women with luminal A tumors -- the least aggressive but most common cancerous breast tumor -- could benefit from extended treatment to improve their chances for long-term survival."

The study appeared Sept. 18 in the journal Cancer Epidemiology, Biomarkers & Prevention.

Breast cancer tumors often are divided into four molecular subtypes, the researchers explained in the news release:

  • Luminal A, which tends to have the best prognosis with fairly high survival rates.
  • Luminal B, which typically occurs in younger women and has a poor prognosis.
  • Basal-like subtype, which also tends to occur in younger women, as well as in black women, and has a poor prognosis.
  • HER2-enriched subtype, which has a fairly poor prognosis and is prone to early and frequent recurrence and metastases (the spread of the disease to other parts of the body).

Of the four subtypes, luminal A accounts for between 42 percent and 59 percent of all breast cancer cases, the release noted.

"These and earlier findings strongly support molecular subtypes as important independent predictors of breast cancer mortality," Haque said. "It is important for women with breast cancer -- even those diagnosed with the least aggressive form of the disease -- to be an advocate for their own health and speak to their doctors about treatment options."

More information

The American Cancer Society has more about breast cancer.

-- Robert Preidt

SOURCE: Kaiser Permanente, news release, Sept. 18, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study finds least aggressive form of breast cancer still poses risk for death years later
2. TAVI improves quality of life in patients with severe aortic stenosis for at least 1 year
3. More Americans Have at Least 2 Chronic Health Issues: CDC
4. Lack of sleep found to be a new risk factor for aggressive breast cancers
5. Gene Might Predict Brain Tumors Aggressiveness
6. The making and unmaking of stem-like, aggressive breast cancer cells
7. Research identifies a promising new therapeutic target for aggressive breast cancer
8. Researchers study vaccine as potential weapon against aggressive brain tumors
9. New lipid screening guidelines for children overly aggressive, UCSF researchers say
10. Cell differentiation as a novel strategy for the treatment of an aggressive type of skin cancer
11. Law Firm Aggressively Litigating against Birth Control Makers for their Newer, but Allegedly Unsafer Products: Nuvaring, Yaz, BeYaz, Yasmin, Ocella, Gianvi
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Least Aggressive Breast Cancer Still Poses Long-Term Risk, Study Finds
(Date:8/19/2017)... ... August 18, 2017 , ... Western University of Health Sciences ... to launch the University’s new Center for Innovation on Wednesday, September 6, 2017. , ... Lecture Hall 1, followed by a technology exhibition from 1 to 3 p.m. showcasing ...
(Date:8/19/2017)... Texas (PRWEB) , ... August 19, 2017 , ... ... with contemporary illustrations of breastfeeding mothers. These illustrations show the diversity ... available in prints in a wide range of sizes. These illustrations are also ...
(Date:8/18/2017)... ... August 19, 2017 , ... ... of Thailand presided over the Amazing Thailand Health and Wellness Tourism Showcase 2017 ... Mr. Noppadon Pakprot, Deputy Governor for Tourism Products and Business at TAT said, ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... of “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... ... August 18, 2017 , ... Radabaugh ... protection assistance to communities in North-Central West Virginia, is embarking on a cooperative ... boys in the area. , The Chestnut Mountain Ranch (CMR) is a Christ-centered ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 million ... continuing operations Second-quarter 2017 ... million Second-quarter 2017 Sterile ... Second-quarter 2017 adjusted diluted earnings ... to $0.93 Second-quarter 2017 ...
(Date:8/7/2017)... , Aug. 7, 2017 Zimmer Biomet Holdings, Inc. ... today announced that its Board of Directors has approved the ... third quarter of 2017. ... on or about October 27, 2017 to stockholders of record ... Future declarations of dividends are subject to approval of the ...
(Date:8/7/2017)...  Diplomat Pharmacy, Inc. (NYSE: DPLO), the nation,s largest independent ... 30, 2017.  All comparisons, unless otherwise noted, are to the ... Second Quarter 2017 Highlights include: ... increase of 3.5% Total prescriptions dispensed of ... 7.5% versus 7.6% Gross profit per ...
Breaking Medicine Technology: