Navigation Links
Least Aggressive Breast Cancer Still Poses Long-Term Risk, Study Finds
Date:9/18/2012

TUESDAY, Sept. 18 (HealthDay News) -- The most common and least aggressive form of breast cancer still poses a risk of death more than 10 years after a woman is diagnosed with the disease, according to a new long-term study.

The findings could affect how doctors treat women with this type of breast cancer, the researchers said.

Their 21-year study of nearly 1,000 women in California found that molecular subtypes of breast cancer were important independent predictors of death from breast cancer. In particular, women with luminal A tumors (a subtype of breast cancer generally believed to have the best prognosis) were still at risk for death from the cancer more than 10 years after their diagnosis.

The researchers at Kaiser Permanente Southern California also found that women with HER2-enriched and luminal B tumors were about twice as likely to die from breast cancer than those with luminal A tumors. That result is consistent with previous research.

"The findings of this study indicate that it is important to consider breast cancer molecular subtypes in determining the optimal treatment for women with breast cancer," study author Reina Haque said in a Kaiser news release. "Women with luminal A tumors -- the least aggressive but most common cancerous breast tumor -- could benefit from extended treatment to improve their chances for long-term survival."

The study appeared Sept. 18 in the journal Cancer Epidemiology, Biomarkers & Prevention.

Breast cancer tumors often are divided into four molecular subtypes, the researchers explained in the news release:

  • Luminal A, which tends to have the best prognosis with fairly high survival rates.
  • Luminal B, which typically occurs in younger women and has a poor prognosis.
  • Basal-like subtype, which also tends to occur in younger women, as well as in black women, and has a poor prognosis.
  • HER2-enriched subtype, which has a fairly poor prognosis and is prone to early and frequent recurrence and metastases (the spread of the disease to other parts of the body).

Of the four subtypes, luminal A accounts for between 42 percent and 59 percent of all breast cancer cases, the release noted.

"These and earlier findings strongly support molecular subtypes as important independent predictors of breast cancer mortality," Haque said. "It is important for women with breast cancer -- even those diagnosed with the least aggressive form of the disease -- to be an advocate for their own health and speak to their doctors about treatment options."

More information

The American Cancer Society has more about breast cancer.

-- Robert Preidt

SOURCE: Kaiser Permanente, news release, Sept. 18, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study finds least aggressive form of breast cancer still poses risk for death years later
2. TAVI improves quality of life in patients with severe aortic stenosis for at least 1 year
3. More Americans Have at Least 2 Chronic Health Issues: CDC
4. Lack of sleep found to be a new risk factor for aggressive breast cancers
5. Gene Might Predict Brain Tumors Aggressiveness
6. The making and unmaking of stem-like, aggressive breast cancer cells
7. Research identifies a promising new therapeutic target for aggressive breast cancer
8. Researchers study vaccine as potential weapon against aggressive brain tumors
9. New lipid screening guidelines for children overly aggressive, UCSF researchers say
10. Cell differentiation as a novel strategy for the treatment of an aggressive type of skin cancer
11. Law Firm Aggressively Litigating against Birth Control Makers for their Newer, but Allegedly Unsafer Products: Nuvaring, Yaz, BeYaz, Yasmin, Ocella, Gianvi
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Least Aggressive Breast Cancer Still Poses Long-Term Risk, Study Finds
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... San Francisco, CA (PRWEB) , ... June 24, ... ... at CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has ... , self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who has ... of the current process. Many of them do not even ... technical difficulties and high laboratory costs involved. And those who ... it at such a high cost that the majority of ... Dr. Parsa Zadeh , founder of Dental Evolutions ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
Breaking Medicine Technology: