Navigation Links
Learning the language of bacteria
Date:12/6/2010

ly fight a much broader range of bacteria."

Finding a broad-spectrum activity for the synthetic lactones is good news, Blackwell adds. "Bacteria come in countless varieties, and the ability to target multiple organisms with one compound could streamline the search for drugs. At the same time, we also have found differences in signal selectivity that may allow us to target some bacteria while ignoring others."

That could provide the best of both worlds, Blackwell says. One drug might halt multiple infections, but related drugs might affect only one microbe in a mixture. "The data indicate that it should be possible to design and use compounds that are either selective or broad-spectrum."

The non-native signaling compounds tested in Blackwell's study were first uncovered in Vibrio fischeri, the bacterium that produces light in the "flashlight squid," which lives in the Pacific Ocean. The flashlight squid and its glowing bacteria have a symbiotic relationship that benefits both parties and have been intensely studied by Ned Ruby and Margaret McFall-Ngai at UW-Madison. But quorum sensing is also active in bacteria that cause disease in animals and plants, Blackwell says.

The need for new ways to control bacteria reflects the rapid evolution and spread of bacterial resistance to the most powerful antibiotics. Antibiotics are no longer a high research priority at most pharmaceutical companies,

Blackwell says. "There is a crisis in antibiotic development, and there is a tremendous need to develop new ways to block bacterial infection. Academics can lead the way by identifying such targets"

Quorum sensing has attracted considerable interest as a way to keep bacteria from "behaving badly," Blackwell says. Because a drug that blocks the quorum signal would not kill bacteria but simply prevent them from releasing toxins and causing disease, "we anticipate that the bacteria are not going to develop resistance as quickly, if a
'/>"/>

Contact: Helen Blackwell
blackwell@chem.wisc.edu
608-262-1503
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Silverchair Learning Systems Enhances Product Expertise with New Hires
2. Learning Lab of Brentwood Leads Free ADHD Seminar
3. H1N1 learnings: Risk factors for severe outcomes among patients admitted to hospital with H1N1
4. A midday nap markedly boosts the brains learning capacity
5. Word learning in deaf children with cochlear implants
6. Rapamycin rescues learning, memory in Alzheimers mouse model
7. UM School of Medicine finds prenatal cocaine exposure not severely damaging to growth, learning
8. Learning keeps brain healthy, UCI researchers find
9. Ritalin Boosts Learning by Increasing Brain Plasticity, According to UCSF Research
10. Study suggests need for broader use of individualized learning plans for physicians
11. Free Brain IQ Quiz, Activities for Home “Brain-Boosting” and Seminar Offered from LearningRX Denver during National Brain Awareness Month
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Angeles, CA (PRWEB) October 20, 2014 ... fitness expertise, nutritional coaching, corporate wellness programming, authorship, international ... CPT, is excited to announce the release of the ... , After many years of coaching thousands of individuals ... nutrition tracking app that does not require calorie counting ...
(Date:10/20/2014)... 2014 Rockynol Retirement Community ... Oct. 14. The $11 million project will include the ... cooked-to-order kitchen with full-service restaurant style dining. , “We ... first class Assisted Living apartments,” said Kara Hanzie, Rockynol ... highest quality of care and this investment is proof ...
(Date:10/20/2014)... Unveiled at the Sept. 18 board meeting, The ... member hospital ROI on membership dues at 12.5. In other ... $12.50 in value to member hospitals. The calculation used to ... Dues. , “This is the first time we’ve actually ... the methodology is really sound,” said Bill Ryan , ...
(Date:10/19/2014)... Hastings and Hastings, a Phoenix personal injury law firm ... Phoenix area and across Arizona reports record demand in ... accidents. Statistics have indicated a steady increase in automobile ... Hastings and Hastings has seen a steady increase in ... been injured through no fault of their own that ...
(Date:10/19/2014)... October 20, 2014 Having been working in ... good knowledge of customer needs. According to James, one of ... with dazzling sequins, or with high-low skirts that add beauty ... huge demand. Recently, LunaDress has unveiled its new selection of ... fact, the company’s brand new items are available in over ...
Breaking Medicine News(10 mins):Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:Rockynol Retirement Community Expands Assisted Living Center 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 2Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 3Health News:Scorecard Estimates Hospital ROI at $12.50 for every $1 Spent on Dues 4Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 2Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 3Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2
... , , WEST PALM BEACH, ... leading providers of he a ring aids ... a hearing care program designed exclusively for AARP members. The program is scheduled ... October and will eventually be extended to AARP members in all 50 states ...
... , Dr. Mubin Syed evaluates findings; ... Ohio, Aug. 11 A new study by Mayo Clinic researchers ... of vertebroplasty to treat osteoporotic spinal fractures. , , ... is injected into vertebrae to relieve pain and improve mobility in ...
... , , Survey seeks feedback from ... , , CHICAGO, Aug. 11 Participate in the American ... and become eligible to win a $150 Amazon.com gift certificate ... , ADA.org provides news and information on hundreds of dental ...
... , , FRAMINGHAM, Mass. and SYDNEY, Aug. ... today announced that it is scheduled to make an investor presentation at ... on Thursday, August 13, 2009. The conference will be held at the ... live webcast of the Company,s presentation at the conference will be available ...
... , , LAKEWOOD, Colo., Aug. 11 ... that its Board of Directors has declared a regular quarterly cash ... September 15, 2009 to shareholders of record at the close of ... Laboratories develops, acquires, manufactures and markets electronic instruments and disposables for ...
... , CLEVELAND, Aug. 11 Herbruck ... convene six medical insurance companies on Thursday, August 20 ... impact of pending federal healthcare legislation on employers. ... important because Americans across the country are discussing and ...
Cached Medicine News:Health News:HearUSA Makes Hearing Aids and Care Available to AARP Members 2Health News:HearUSA Makes Hearing Aids and Care Available to AARP Members 3Health News:HearUSA Makes Hearing Aids and Care Available to AARP Members 4Health News:Noted Vertebroplasty Expert Cites Concerns About Recently Published Study 2Health News:American Dental Association Web Survey Offers Chance at $150 Gift Certificate 2
(Date:10/17/2014)... , Oct. 17, 2014 With the ... Affairs function has come across several challenges in ... and managing globalization.  The ... is dedicated to providing benchmarking and best practices ... Consortium is a service composed of three stages: ...
(Date:10/17/2014)... 2014  Hanger, Inc. (NYSE: HGR ) ... of operations for the quarter ended September 30, 2014, ... A conference call to discuss these results is scheduled ... 7, 2014. Those wishing to participate should call 1-877-662-6095. ... 2014 by dialing 1-855-859-2056 and referencing Conference ID # ...
(Date:10/17/2014)... 2014 UBM Medica US announces that ... and information resource for neurologists and other healthcare providers, features ... disease , with discussions of the latest developments in approaches ... have Parkinson disease , more than the total of those ... disease. Diagnosis can be difficult because there are no ...
Breaking Medicine Technology:Early Key Findings from the Medical Affairs Consortium Research 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3
... Business Council is pleased to announce that General Electric (GE), ... joint ventures in Russia. These joint ventures bolster GE,s position ... power generation and healthcare sectors. Under the ... billion in sales, GE will sell at least 77 gas ...
... NEW YORK, Sept. 16, 2011 Choosing ... be a confusing process.  Referrals from peers and subsequent ... experience and results.  Patients need to be educated on ... go in search of a plastic surgeon for treatment. ...
Cached Medicine Technology:USRBC President Ed Verona Lauds GE Announcement on Energy and Healthcare Joint Ventures in Russia 2Trust Your Derm: The JUVA Skin & Laser Center Advises Patients To Seek Board Certified Dermatologists and AAAHC Accredited Facilities For Safe Cosmetic Procedures 2
Chin Implants are used for cosmetic augmentation, repairing trauma related injuries and genetic deficiencies. They are inserted through an incision in the mouth below the incisor teeth or through an ...
... The IEC CL40 and FL40 ... power, safety and versatility to increase ... with a broad array of rotors ... processing and microplate applications, the IEC ...
... The IEC CL30 Series from ... exceptional value for your low-speed ... AUTO-LOCK rotor exchange system, user-friendly ... the IEC CL30 Series delivers ...
Chembio Diagnostic Systems, Inc.s SURE CHECK HIV 1 / 2, HIV 1/ 2 STAT-PAK and HIV 1/ 2 STAT-PAK Dipstick tests are easy-to-perform, single-use diagnostic tests for the rapid, visual detection of anti...
Medicine Products: