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Laureate Announces Second Manufacturing Agreement with Cytheris
Date:3/27/2008

Laureate to Manufacture Cytheris' Lead Product Candidate, INTERLEUKIN-7,

currently in clinical trials for treatment of HIV, HCV and cancer

PRINCETON, N.J. and PARIS, March 27 /PRNewswire-FirstCall/ -- Laureate Pharma, Inc., a full-service biopharmaceutical development and protein production company, announced today that it has entered into a cGMP contract manufacturing agreement with Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation. According to the agreement, Laureate will manufacture Cytheris' lead product candidate, Interleukin-7 (IL-7), a fully glycosylated recombinant human protein and critical growth factor for immune T-cell recovery, for use in ongoing international clinical trials currently being conducted for treatment of HIV, HCV and cancer. Terms and conditions of the agreement were not disclosed.

(Logo: http://www.newscom.com/cgi-bin/prnh/20080131/NETH020LOGO )

Recombinant human Interleukin-7 (r-hIL-7) is a critical growth factor for immune T-cell recovery and enhancement. Clinical investigations conducted on more than 75 patients in Europe, the U.S. and Canada have suggested the potential of r-hIL-7 to expand and protect CD4+ and CD8+ T-cells.

"We are delighted that Cytheris has selected us again as their CMO, to manufacture IL-7 in support of their expanded clinical trial program. This is a testimonial to our successful partnership with our clients and our effort to achieve their total satisfaction in our ability to meet their manufacturing needs," said Robert J. Broeze, Ph.D., President & CEO of Laureate. "We will work with the Cytheris team very closely and help them realize the greatest potential of their IL-7 development and production program."

"As we move towards large scale production of our IL-7 biotherapeutic, we are pleased to conti
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SOURCE Laureate Pharma, Inc.
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