Navigation Links
Latest Study Says Statins Don't Slow Alzheimer's
Date:1/17/2008

Final answer may depend on outcomes of ongoing clinical trials, expert says

THURSDAY, Jan. 17 (HealthDay News) -- Despite some reports that statins might slow or prevent Alzheimer's disease, a new study finds no evidence for the theory.

While some animal studies have suggested this possibility, whether the same benefit translates to humans hasn't been clear, the researchers said.

"We didn't find a relation between statin use and the risk of Alzheimer's disease or a decline in thinking ability," said lead researcher Dr. Zoe Arvanitakis, an associate professor of neurology at Rush University Medical Center in Chicago.

In addition, brain autopsies found no effect of statins on the two main causes of dementia, Alzheimer's and stroke, Arvanitakis said.

In the study, Arvanitakis' team collected data on 929 Catholic clergy who took part in the Religious Orders Study, which looks at aging and Alzheimer's disease. At the start of the study, all the participants were around 75 years old and had no signs of dementia. All had a brain autopsy after death, and each had yearly cognitive exams for up to 12 years.

The findings were published in the Jan. 16 online edition of Neurology.

When the study started, 119 people were taking statins. Over the 12 years of the study, 191 people developed Alzheimer's. Of these, only 16 had been taking statins.

Moreover, brain autopsies on more than 250 people who died during the study failed to find any evidence that taking statins had an effect on pathology of Alzheimer's disease or strokes, the scientists found.

"This study adds to the growing evidence that statins don't lower the risk of Alzheimer's disease," Arvanitakis said.

However, one expert thinks this study is not conclusive, and clinical trials that are under way should provide a definitive answer on the issue. "We will see the results of these trials fairly soon," said William Thies, vice president of medical and scientific affairs for the Alzheimer's Association.

"This finding fits in with a great deal of other work that has been done on statins," said Thies. "Most of these studies show a benefit, but this is not the first one to show there isn't a benefit."

Statins are excellent drugs for lowering cholesterol, Thies said. "But there is no recommendation that you take statins for Alzheimer's disease," he added.

Larry Sparks, director of the Roberts Laboratory for Neurodegenerative Disease Research at the Sun Health Research Institute in Arizona and one of the first to link statins with Alzheimer's prevention, doesn't think the study was large enough to give a definitive result.

In his own work, Sparks has found a benefit from statins in treating patients with mild to moderate Alzheimer's disease. However, he thinks the type of statin makes a difference.

"Research suggests that statins that don't get into the brain may prevent or slow the progression of Alzheimer's," Sparks said. "This is a continuing story."

More information

For more on Alzheimer's disease, visit the Alzheimer's Association.



SOURCES: Zoe Arvanitakis, M.D., associate professor, neurology, Rush University Medical Center, Chicago; William Thies, Ph.D., vice president, medical and scientific affairs, Alzheimer's Association, Chicago; Larry Sparks, Ph.D., director, Roberts Laboratory for Neurodegenerative Disease Research, Sun Health Research Institute, Sun City, Ariz.; Jan. 16, 2008, Neurology online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cancer study finds adolescents dont get same access to latest treatments as younger patients
2. Statement from AAJ President Kathleen Flynn Peterson on ATRAs Latest Attack on Civil Justice Attorneys
3. A Whole New Sandwich Debuts in the Freezer Aisle: LEAN POCKETS(R) Brand Introduces Latest Whole Grain Varieties
4. AST Emergence to Convergence Highlights the Latest High-Risk Organ Donor and Recipient Issues
5. Latest Edition of Ripon Forum Highlights Schwarzeneggers Leadership on Another Challenge Facing his State - Health Care
6. Cejka Search Experts Present Latest Developments in Physician and Healthcare Employment at Leading Industry Conferences
7. The latest about male infertility and testosterone from NewYork-Presbyterian/Weill Cornell
8. Actor Joe Pantoliano Discloses Depression; Talks About His Latest Movie and His Sensitive Side
9. Big Tobaccos Latest Dirty Trick: Deceiving Oregon Voters
10. The Leukemia & Lymphoma Society Provides Patients with the Latest Information on Myeloma
11. PA Governor Rendell Announces Latest Nominations and Appointments
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Latest Study Says Statins Don't Slow Alzheimer's
(Date:9/20/2017)... ... September 20, 2017 , ... In just a short time ... already been receiving positive feedback from customers trying the product for the first time, ... Brain Booster was developed by neurosurgeon Shawn Moore, MD, for everyone from athletes at ...
(Date:9/20/2017)... ... ... The Centers for Medicare and Medicaid Services (CMS) stated in the Inpatient ... Worksheet S-10 to distribute Disproportionate Share Hospital (DSH) Uncompensated Care Payments over the next ... on October 17, 2017 at 2 P.M. EST and uncover how you can prepare ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... feel good program from Leany Greeny delivers positive results in just three weeks. ... health and kickstart the metabolism. Fitting seamlessly into hectic work and family schedules, ...
(Date:9/20/2017)... ... September 20, 2017 , ... “Finn Mouseson”: follows the exciting ... an average life. This mouse sets out on a journey that will show that ... is the creation of newly published author and illustrator, Melody Gersonde-Mickelson, who has earned ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... “Psalms of ... give peace of mind and move the readers one step closer to God. “Psalms ... has realized that his mistakes that have been made within his life are the ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... , Sept. 6, 2017 NeuroRx, a clinical ... Suicidal Ideation and Behavior (ASIB), has been granted Fast Track ... sequential therapy of NRX-100 (ketamine HCl) followed by NRX-101 (D-cycloserine ... a pivotal trial of this sequential therapy targeting patients who ... 1 ...
(Date:9/5/2017)... , Sept. 5, 2017  Just 18 months ... Insight is pleased to announce the appointment of three ... Tammy Wynne , Dominic Jones-Phillips and ... industry. Tammy ... team of market access writers. She has over ten ...
(Date:8/31/2017)... PM360,s annual Innovations Issue, published in ... innovations happening across the industry. Established six years ago, ... providing a comprehensive look at the newest and most ... innovative companies, startups, divisions, products, services, and strategies from ... "Everyone in this industry wants to do better—in all ...
Breaking Medicine Technology: