Navigation Links
Latest Study Says Statins Don't Slow Alzheimer's
Date:1/17/2008

Final answer may depend on outcomes of ongoing clinical trials, expert says

THURSDAY, Jan. 17 (HealthDay News) -- Despite some reports that statins might slow or prevent Alzheimer's disease, a new study finds no evidence for the theory.

While some animal studies have suggested this possibility, whether the same benefit translates to humans hasn't been clear, the researchers said.

"We didn't find a relation between statin use and the risk of Alzheimer's disease or a decline in thinking ability," said lead researcher Dr. Zoe Arvanitakis, an associate professor of neurology at Rush University Medical Center in Chicago.

In addition, brain autopsies found no effect of statins on the two main causes of dementia, Alzheimer's and stroke, Arvanitakis said.

In the study, Arvanitakis' team collected data on 929 Catholic clergy who took part in the Religious Orders Study, which looks at aging and Alzheimer's disease. At the start of the study, all the participants were around 75 years old and had no signs of dementia. All had a brain autopsy after death, and each had yearly cognitive exams for up to 12 years.

The findings were published in the Jan. 16 online edition of Neurology.

When the study started, 119 people were taking statins. Over the 12 years of the study, 191 people developed Alzheimer's. Of these, only 16 had been taking statins.

Moreover, brain autopsies on more than 250 people who died during the study failed to find any evidence that taking statins had an effect on pathology of Alzheimer's disease or strokes, the scientists found.

"This study adds to the growing evidence that statins don't lower the risk of Alzheimer's disease," Arvanitakis said.

However, one expert thinks this study is not conclusive, and clinical trials that are under way should provide a definitive answer on the issue. "We will see the results of these trials fairly soon," said William Thies, vice president of medical and scientific affairs for the Alzheimer's Association.

"This finding fits in with a great deal of other work that has been done on statins," said Thies. "Most of these studies show a benefit, but this is not the first one to show there isn't a benefit."

Statins are excellent drugs for lowering cholesterol, Thies said. "But there is no recommendation that you take statins for Alzheimer's disease," he added.

Larry Sparks, director of the Roberts Laboratory for Neurodegenerative Disease Research at the Sun Health Research Institute in Arizona and one of the first to link statins with Alzheimer's prevention, doesn't think the study was large enough to give a definitive result.

In his own work, Sparks has found a benefit from statins in treating patients with mild to moderate Alzheimer's disease. However, he thinks the type of statin makes a difference.

"Research suggests that statins that don't get into the brain may prevent or slow the progression of Alzheimer's," Sparks said. "This is a continuing story."

More information

For more on Alzheimer's disease, visit the Alzheimer's Association.



SOURCES: Zoe Arvanitakis, M.D., associate professor, neurology, Rush University Medical Center, Chicago; William Thies, Ph.D., vice president, medical and scientific affairs, Alzheimer's Association, Chicago; Larry Sparks, Ph.D., director, Roberts Laboratory for Neurodegenerative Disease Research, Sun Health Research Institute, Sun City, Ariz.; Jan. 16, 2008, Neurology online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cancer study finds adolescents dont get same access to latest treatments as younger patients
2. Statement from AAJ President Kathleen Flynn Peterson on ATRAs Latest Attack on Civil Justice Attorneys
3. A Whole New Sandwich Debuts in the Freezer Aisle: LEAN POCKETS(R) Brand Introduces Latest Whole Grain Varieties
4. AST Emergence to Convergence Highlights the Latest High-Risk Organ Donor and Recipient Issues
5. Latest Edition of Ripon Forum Highlights Schwarzeneggers Leadership on Another Challenge Facing his State - Health Care
6. Cejka Search Experts Present Latest Developments in Physician and Healthcare Employment at Leading Industry Conferences
7. The latest about male infertility and testosterone from NewYork-Presbyterian/Weill Cornell
8. Actor Joe Pantoliano Discloses Depression; Talks About His Latest Movie and His Sensitive Side
9. Big Tobaccos Latest Dirty Trick: Deceiving Oregon Voters
10. The Leukemia & Lymphoma Society Provides Patients with the Latest Information on Myeloma
11. PA Governor Rendell Announces Latest Nominations and Appointments
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Latest Study Says Statins Don't Slow Alzheimer's
(Date:5/26/2017)... , ... May 26, 2017 , ... ... announce a new educational seminar to focus on current legislative activity and the ... will begin at 1 p.m. Sunday, Sept. 10, and will continue through Monday, ...
(Date:5/26/2017)... ... May 26, 2017 , ... A new analysis of ... the healthiest seniors are located in the Midwest. With the average cost of healthcare ... people are concerned with both the quality and affordability of where they live. An ...
(Date:5/26/2017)... ... May 26, 2017 , ... On May 24, the Congressional Budget ... the U.S. House on May 4, would result in 23 million Americans losing their ... of the 2010 Patient Protection and Affordable Care Act (ACA). , “It is ...
(Date:5/26/2017)... ... May 26, 2017 , ... Silver Birch of Hammond, ... is located on more than four acres of land at 5620 Sohl Avenue in ... The 103,000 square-foot building includes 125 studio and one-bedroom apartments. Each of the private ...
(Date:5/26/2017)... ... ... “When the Stars Lead Home”: a poignant story of loss, determination, and ... Douglas, an avid reader who lives in the Pacific Northwest with her husband, daughter, ... Adventure Camp. She couldn’t be more grateful. , Twelve-year old Tizzy could not believe ...
Breaking Medicine News(10 mins):
(Date:5/26/2017)... , May 25, 2017  In response to ... , Direct Relief is working with Pfizer to ... available at no cost to community health centers, free ... providers nationwide. "Pfizer has a long-standing ... medicines and ensuring patient safety through educational activities," said ...
(Date:5/18/2017)... 2017  Two Bayer U.S. Pharmaceutical leaders received top ... recent 28 th Woman of the Year ... HBA,s longstanding mission of furthering the advancement and impact ... Cindy Powell-Steffen , senior director of brand activation ... Libby Howe , a regional business manager for ...
(Date:5/11/2017)... May 11, 2017  Thornhill Research Inc. ( ... awarded an $8,049,024 USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract ... Canadian Commercial Corporation (CCC) ( Ottawa, Ontario, ... to administer general anesthesia to patients requiring emergency ... "The US Marine Corps have been a longtime ...
Breaking Medicine Technology: