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Latest Pistachio Study Reveals Significant Reduction in Markers of Inflammation - an Emerging Risk Factor in Heart Disease
Date:10/27/2008

mption (approximately 1.5 oz and 3.0 oz). The study positively supports other recent studies that show a diet rich in pistachios helps improve heart disease risk factors, in this case, inflammation. It also furthered researchers' understanding of differences in response to diet. Some individuals were responsive to diet changes while others were not. More research is needed to further understand the reasoning behind diet responders versus non-responders. Ultimately, this will lead to a more individualized approach for dietary guidance.

Study Highlights

-- Diets that incorporate pistachios significantly reduce the expression of inflammation-related genes when compared to an average American diet (higher in total fat and saturated fat).

-- Responses to diet changes are variable -- some individuals are diet-responsive while others are not. Further research is needed to better understand reasons for responders versus non-responders.

-- Following consumption of the pistachio diets, some individuals had diet-induced changes (diet responders) in cholesteryl ester transfer protein (CETP) -- a key protein involved in cholesterol metabolism.

-- In diet responders, changes in CETP expression at the cellular level indicated changes in heart disease risk factors in the blood -- such as LDL-cholesterol. Results suggest that changes in gene expression may help explain changes in heart disease risk factors following consumption of pistachio diets.

"The Western Pistachio Association is dedicated to funding research and promoting nutrition news about pistachios and health," says Dr. Constance Geiger, nutrition expert for the Western Pistachio Association (WPA). "We're eager to fund additional research that will look at the effect of pistachios on prevention of chronic disease risk factors, which will help to better-predict positive changes within the body."

Pistachios Pack Powerful Nutrition

In July 2003, the U.S. Food and Drug A
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SOURCE Western Pistachio Association
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