Navigation Links
Late-life depression associated with prevalent mild cognitive impairment, increased risk of dementia
Date:12/31/2012

CHICAGO Depression in a group of Medicare recipients ages 65 years and older appears to be associated with prevalent mild cognitive impairment and an increased risk of dementia, according to a report published Online First by Archives of Neurology, a JAMA Network publication.

Depressive symptoms occur in 3 percent to 63 percent of patients with mild cognitive impairment (MCI) and some studies have shown an increased dementia risk in individuals with a history of depression. The mechanisms behind the association between depression and cognitive decline have not been made clear and different mechanisms have been proposed, according to the study background.

Edo Richard, M.D., Ph.D., of the University of Amsterdam, the Netherlands, and colleagues evaluated the association of late-life depression with MCI and dementia in a group of 2,160 community-dwelling Medicare recipients.

"We found that depression was related to a higher risk of prevalent MCI and dementia, incident dementia, and progression from prevalent MCI to dementia, but not to incident MCI," the authors note.

Baseline depression was associated with prevalent MCI (odds ratio [OR], 1.4) and dementia (OR, 2.2), while baseline depression was associated with an increased risk of incident dementia (hazard ratio [HR], 1.7) but not with incident MCI (HR, 0.9). Patients with MCI and coexisting depression at baseline also had a higher risk of progression to dementia (HR, 2.0), especially vascular dementia (HR, 4.3), but not Alzheimer disease (HR, 1.9), according to the study results.

"Our finding that depression was associated cross sectionally with both MCI and dementia and longitudinally only with dementia suggests that depression develops with the transition from normal cognition to dementia," the authors conclude.


'/>"/>

Contact: Elizabeth Streich
eas2125@columbia.edu
212-305-3689
JAMA and Archives Journals
Source:Eurekalert

Page: 1

Related medicine news :

1. Winter Depression May Require Treatment Plan
2. Blood Protein Linked to Depression, Study Finds
3. Elevated levels of C-reactive protein appear associated with psychological distress, depression
4. Sibling squabbles can lead to depression, anxiety
5. Dr. Garber's Natural Solutions, Unique, Condition Specific Natural Remedies including Sleep, Anxiety and Depression, Goes International
6. Stress, Depression Linked to Raised Stroke Risk in Seniors
7. Experimental agent briefly eases depression rapidly in test
8. ACNP: Novel NMDA receptor modulator significantly reduces depression scores within hours
9. Best Christmas Gift for 2012: Instant Stress Relief on CD! Relaxintuit.com’s Award-Winning Meditation CD Soothes Anxiety, Depression, Pain & Supports Deep, Healthy Sleep
10. Behavior problems, not depression, linked to lower grades for depressed youths
11. Depression a Key Factor in Health of Parkinsons Patients: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... ... ... reminds us that May is National Stroke Awareness Month. According to the Centers for ... the United States; someone has one every 40 seconds. Annually, almost 800,000 strokes occur ... A stroke is when blood flow to the brain is blocked or when a ...
(Date:4/28/2016)... MA (PRWEB) , ... April 28, 2016 , ... A ... were typical among 18 states studied, the Workers Compensation Research Institute (WCRI) ... The WCRI study, CompScope™ Benchmarks for Kentucky, 16th Edition , found that indemnity ...
(Date:4/28/2016)... ... April 28, 2016 , ... SyncDog, Inc. ... its leading secure mobility workstation suite, SentinelSecure™, at MobileIron’s 6th annual Mobile First ... this will be MobileIron’s 6th Mobile First Conference and will feature immersive training, ...
(Date:4/28/2016)... ... 2016 , ... For the 10,000 Americans who turn 65 on any given ... overall well-being: mental health. Now, a new book—Staying Sharp For Dummies (Paper; ISBN: 978-1-119-18779-0; ... which can include everything from honing your memory and managing stress to eating healthy ...
(Date:4/28/2016)... , ... April 28, 2016 , ... The USDA recently ... based on the latest nutritional science. While there is a lot of information available ... health, according to the April 2016 issue of Harvard Men's Health Watch . ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016 Transparency Market ... Devices Market - Global Industry Analysis, Size, Share, Growth, ... report, the global skincare devices market was valued at ... expand at a CAGR of 10.1% from 2015 to ... Browse the full Skincare Devices Market (Treatment Device - ...
(Date:4/27/2016)... Shire plc (LSE: SHP, NASDAQ: SHPG ... will present at the Deutsche Bank 41st Annual Health Care ... May 04, 2016, 10:00 am EDT (15:00 BST). ... and Webcasts section of Shire,s Investor website at http://investors.shire.com/presentations-and-webcasts/ ... on this same website for approximately 90 days. ...
(Date:4/27/2016)... 27, 2016 The global  ... 2.06 billion by 2022, according to a new ... awareness towards a healthy lifestyle is expected to ...      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) ... rising health treatment expenditure has urged consumers to ...
Breaking Medicine Technology: