Navigation Links
Laser-light testing of breast tumor fiber patterns helps show whose cancer is spreading
Date:11/1/2012

Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

The Johns Hopkins researchers say their crisscrossing optical images, made by shining a laser back and forth across a biopsied tissue sample a few millionths of a meter thick, can potentially be used with other tests to more accurately determine the need for lymph node biopsy and removal in women at risk of metastatic breast cancer.

In what is believed to be the first study to measure minute changes in tumor connective tissue fibers, researchers found that eight women whose cancers had spread beyond the breast through the body's lymphatic system had about 10 percent more densely packed and radially spread-out collagenous structural proteins than six women whose cancers had not yet spread. Collagen fibers in the non-metastasized tumors, also obtained during breast biopsy, were more diffuse and arranged in a transverse or horizontal pattern. All 14 women in the study had aggressive, malignant breast cancer.

In the new report, to be published in the Journal of Biomedical Optics online Nov. 1, researchers say that if these "proof of principle" findings hold up in testing now under way in hundreds more women with or without metastatic breast cancer, then their new optical imaging tool could simplify testing for spreading disease and help people avoid unnecessary lymph node surgery.

"Our new diagnostic technique has the potential to help reassure thousands of breast cancer patients that their cancers have not spread to other organs, and could help them avoid the risks and pain currently involved in direct inspections of lymph nodes for the presence of cancerous cells," says study senior investigator Kristine Glunde, Ph.D.


'/>"/>
Contact: David March
dmarch1@jhmi.edu
410-955-1534
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Water quality study shows need for testing at state migrant camps
2. Researchers show cost-effectiveness of HIV testing in drug abuse treatment programs
3. Engineers improve blood testing technology with smartphone app, hand-held biosensor
4. Joint EACPR and AHA statement empowers health care professional to use Clinical Cardiopulmonary Exercise Testing
5. PSA Testing Linked to Improved Prostate Cancer Survival
6. Sensor detects glucose in saliva and tears for diabetes testing
7. Prostate cancer survival rates improved since introduction of PSA testing
8. HIV home testing kits prove their worth
9. By studying animal health, researchers find improved ways for developing, testing cancer therapies
10. Heterogeneous ER+ breast cancer models allow more accurate drug testing
11. What would happen without PSA testing?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... chemotherapy over the past decade, but targeting drugs to ... a major challenge. , Nanotechnology has unlocked new ... nanocarriers, or capsules, that can transport cargoes of small-molecule ... catch? These carriers are tiny, and it matters just ... nanometers to 100 nanometers, and the drugs can end ...
(Date:4/14/2014)... reached a medical milestone April 3, performing the ... way to access the heart. , Henry Ford ... performing the unique procedure called transcaval valve replacement, ... blood vessels. , Northern Michigan resident Viola Waller, ... July 3, 2013 when traditional valve replacement was ...
(Date:4/14/2014)... one of the scientific marvels of the 20th century, ... won against bacterial infections. But scientists at the University ... to restoring its combat effectiveness, even against so-called "superbugs." ... of the penicillin family of drugs since their first ... the staph infection, brought about by the bacterium ...
(Date:4/14/2014)... in their radiation treatment decisions leaves cancer patients ... even relieve psychological distress around the experience, researchers ... the University of Pennsylvania report in the ... of 305 patients undergoing radiation treatment, Neha ... department in Radiation Oncology at Penn Medicine, and ...
(Date:4/14/2014)... Popular web information on colorectal cancer is too difficult ... the appropriate risks to and concerns of patients, a ... In a review of a dozen popular websites, most ... screening were written beyond the recommended sixth-grade reading level, ... risks, as well as the barriers to and benefits ...
Breaking Medicine News(10 mins):Health News:Nano shake-up 2Health News:Henry Ford Hospital hits new heart valve surgery milestone 2Health News:Penicillin redux: Rearming proven warriors for the 21st century 2Health News:Penicillin redux: Rearming proven warriors for the 21st century 3Health News:Shared decision making during radiation therapy improves patient satisfaction 2Health News:Shared decision making during radiation therapy improves patient satisfaction 3Health News:Website information on colon cancer too complex, fails to address key concerns 2Health News:Website information on colon cancer too complex, fails to address key concerns 3
... -- The prestigious BBVA Foundation Frontiers of Knowledge Award ... J. Lefkowitz, M.D., James B. Duke Professor of Medicine ... investigator at Duke University Medical Center. This is only ... Dr. Lefkowitz,s research has affected millions of cardiac and ...
... U.S. Department of Energy,s National Nuclear Security Administration (NNSA) ... of radioisotopes, which are used to help millions of ... cancer, thyroid and heart disease. Earlier this week, ... develop a U.S. supply of Molybdenum-99 (Mo-99). Babcock & ...
... a new generation of products aimed at making cleaning ... in the current issue of Chemical & Engineering News ... Editor Michael McCoy points out in the cover story ... occurring despite a rocky economy in 2009, which led ...
... scent of urine could catch disease quickly , WEDNESDAY, Jan. 27 ... that can detect lung cancer simply on the basis of a ... is so far based solely on work with mice, but follow-up ... in the early diagnosis of lung cancer in humans. , "But ...
... ... regenerates dormant hair follicles to produce new growth is not being recommended by the researchers ... effective hair loss treatment options are already available. , ... (PRWeb UK) January 28, 2010 -- Researchers and hair restoration surgeons ...
... , WASHINGTON , Jan. 27 ... (SCAI) launched "WINHeart -- Score a WIN for Women," ... the diagnosis, treatment and survival of women with cardiovascular ... of interventional cardiologists within SCAI, today released a new ...
Cached Medicine News:Health News:Renowned Duke researcher wins Frontiers of Knowledge Award 2Health News:SNM applauds US Department of Energy's move to develop domestic radioisotope supply 2Health News:New Test Might 'Smell' Early Stage Lung Cancer 2Health News:New Test Might 'Smell' Early Stage Lung Cancer 3Health News:Hair Cloning Not Yet Recommended by Researchers Who Developed the Technique 2Health News:New Report and Survey Findings Highlight Why More Women Die From Heart Disease Than Men 2Health News:New Report and Survey Findings Highlight Why More Women Die From Heart Disease Than Men 3Health News:New Report and Survey Findings Highlight Why More Women Die From Heart Disease Than Men 4Health News:New Report and Survey Findings Highlight Why More Women Die From Heart Disease Than Men 5
(Date:1/15/2014)... Jan. 15, 2014  Novation, the leading health ... awarded several new IT value-added reseller (VAR) national ... organizations with IT goods and services at lower ... as well as value-added services such as initiative ... New Novation agreements were awarded to CDW ...
(Date:1/15/2014)... -- BreedIT Corp (OTC: BRDT), through its ... highly sophisticated agro-breeding solutions for plant breeders and researchers, ... board of directors appointed chemistry and pharmaceutical industry expert ... of the board. From 1975 to 2012, ... Ltd (NYSE: TEVA ) and its subsidiaries ...
(Date:1/15/2014)...  Echo Therapeutics, Inc. (Nasdaq: ECTE ... Symphony® CGM System as a non-invasive, wireless continuous ... F. Doman , Executive Chairman and Interim CEO ... Financial Capital Markets, Tenth Annual Equity Conference. ... presentation to prospective corporate partners and investors at ...
Breaking Medicine Technology:New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... ... a new market research report is available in its ... A Worldwide Market Review , http://www.reportlinker.com/p0164338/Respiratory-Care-Equipment--Supplies---A-Worldwide-Market-Review.html ... driving the respiratory care equipment & supplies market. Novel ...
... , NEW YORK, Dec. 8 ... is available in its catalogue: , Training Manikins ... Training manikins, capable of replicating real-life trauma conditions, are ... are in use across various institutions including hospitals, military, ...
Cached Medicine Technology:Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 2Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 3Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 4Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 5Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 6Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 7Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 8Reportlinker Adds Respiratory Care Equipment & Supplies - A Worldwide Market Review 9Reportlinker Adds Training Manikins - Global Trends 2Reportlinker Adds Training Manikins - Global Trends 3Reportlinker Adds Training Manikins - Global Trends 4Reportlinker Adds Training Manikins - Global Trends 5
Universal Hub with Varying Blade Edge Diameters For Mounting the Blade to the Handle; Stainless Steel....
2 Sided Pivoted Closed Ring Design,Pointed And Smooth Sides; in stainless steel....
Blunt Tapered Tip in stainless steel....
... meet the high-quality and ... practices. The optional Profile ... accessory features a unique ... increases the accuracy of ...
Medicine Products: