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Largest ever study of childhood ALL shows improving survival
Date:3/14/2012

e's still more work to be done."

According to Hunger, this work is likely to take two forms: predicting high-risk ALL patients early enough to affect treatment decisions, and the development of new, targeted therapies.

For example, adding the drug imatinib (gleevec) to the treatment of children with ALL that have a specific alteration known as the Philadelphia chromosome nearly doubled survival. In the next ten years, Hunger hopes similarly targeted drugs will chip away at the remaining 10 percent ALL mortality.

"I actually met a person last year who was one of the first kids cured at Children's Hospital, in the late 1960s he's my age and works at the airport," Hunger says. "He talked about watching most of the children he met with ALL die. Now almost all will live."

For Hunger and other members of his group, "almost all" is not enough.


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Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

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