Navigation Links
Largest ever study of childhood ALL shows improving survival
Date:3/14/2012

A 21,626-person study published today in the Journal of Clinical Oncology found that the five-year survival rate for children and adolescents with acute lymphoblastic leukemia (ALL), the most common childhood cancer, improved from 83.7 percent in those diagnosed during the years 1990-1994, to 90.4 percent for those diagnosed in the years 2000-2005.

"The improved survival is due to using existing drugs better, not because of the introduction of new drugs. We're indebted to all the families who choose to join these clinical trials, allowing us to optimize these combinations," says Stephen Hunger, MD, investigator at the University of Colorado Cancer Center, professor of pediatrics at the University of Colorado School of Medicine, and director of the Center for Cancer and Blood Disorders at Children's Hospital Colorado, the study's lead author.

Data included all patients aged 0-22 years who received treatment on a Children's Oncology Group clinical trial, between 1990 and 2005. These patients represented an estimated 55.8 percent of ALL cases diagnosed in the United States during this period.

"I wonder how much more we could improve therapy for, say, breast cancer if half of all women with that disease were enrolled in clinical trials," Hunger says.

Additional findings include significant improvements in survival for African American patients with ALL, which narrowed the racial survival gap. Also, the only group in which survival didn't increase during this period was infants less than one year old, whose decrease in death from leukemia relapse was offset by an increase in treatment-related mortality.

"In early 1960s this disease was incurable," Hunger says. "Then in the late 1960s, the cure rate was 10 percent. Now almost 90 percent of children and adolescents diagnosed with ALL will be cured. Still, a 90-percent survival rate is little consolation to the 10 percent of families whose child doesn't survive. Ther
'/>"/>

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related medicine news :

1. An invitation to Europes largest forum on breast cancer
2. Reserve your place at the largest bone event in Europe
3. NDAR federation creates largest source of autism research data to date
4. Nations largest federation of biological and biomedical organizations welcomes 2 new members
5. Save the date: National meeting of the worlds largest scientific society
6. Unvaccinated Kids Behind Largest U.S. Measles Outbreak in Years: Study
7. Largest global childhood pneumonia etiology study launched
8. Worlds largest meeting of ear, nose and throat doctors
9. Largest Ob/Gyn Group Backs Annual Mammograms in 40s
10. TEMLA shows higher diagnostic yield than EBUS or EUS in largest reported series to date
11. Dubai to host largest clinical bone meeting in the Middle East and Africa region
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... Ellen V. Krieger, DDS released a new video describing her ... to describe the business and industry best practices for ... of cosmetic and family dentistry experience, Dr Ellen Krieger is ... and cared for. , Dr. Krieger has practiced dentistry in ... solid reputation of offering bright, friendly service to all of ...
(Date:8/27/2014)... August 27, 2014 Top10BestSEOHosting.com compares ... and GoDaddy are the most recommended suppliers for ... products. , “GreenGeeks and GoDaddy provide stellar ... believe that they have managed to provide a ... an intuitive ease of use that helps diminish ...
(Date:8/27/2014)... CA (PRWEB) August 27, 2014 DiabetesSisters ... event in collaboration with Diabetes Community Advocacy Foundation (DCAF) ... October 24-25, 2014 at Embassy Suites LAX North. The ... Media Meetup featuring DSMA Live”, an event which is ... evening, October 24th. , Interactive in many ways, DiabetesSisters’ ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 The world ... transformation as was revealed in a survey conducted recently ... not just surprising but astonishing as well, and for ... online interviewed existing members on the 10yeargap website and ... to Kaly, 10yeargap marketing department manager," there are more ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 ... governance, and compliance software solutions for next-generation social ... Inc. magazine’s Inc. 500|5000, an exclusive ranking of ... consecutive year. AvePoint joins brands such as Alex ... 2014 edition. , This underscores continued growth ...
Breaking Medicine News(10 mins):Health News:Ellen V. Krieger, DDS of McLean, Virginia Announces New Video Describing Industry Best Practices 2Health News:Excellent Hosting Suppliers Recommended By Top10BestSEOHosting.com 2Health News:DiabetesSisters and Diabetes Community Advocacy Foundation Join Forces to Bring Together People with Diabetes in Los Angeles 2Health News:DiabetesSisters and Diabetes Community Advocacy Foundation Join Forces to Bring Together People with Diabetes in Los Angeles 3Health News:Survey Reveals Younger Women Dating Older Men 2Health News:Survey Reveals Younger Women Dating Older Men 3Health News:Inc. Magazine Names AvePoint to the Inc. 500|5000 List of Fastest Growing American Companies for the Fifth Consecutive Year 2Health News:Inc. Magazine Names AvePoint to the Inc. 500|5000 List of Fastest Growing American Companies for the Fifth Consecutive Year 3
... discovered previously unsuspected mutations that contribute to the formation ... common cancer in children. The discovery not only suggests ... a roadmap for the identification of unsuspected mutations in ... in which immature white blood cells that normally develop ...
... grim facts to state. The study estimates that more than ... and that it also takes more than two years to ... 125,000 Australians suffer from some sort of autism indicted by ... this means that autism affects half a million Australians. ...
... findings by Dutch researchers suggest that the hormone glucocorticoids ... to be//. The steroid is prescribed by many specialists ... ,The steroid hormones called glucocorticoids are employed by ... to influence the body’s immune responses in a good ...
... A medical college counsellor set afire by his patient ... Chandra Bose Medical College hospital// in Jabalpur where the ... counsellor, Sanjay Shrivastava suffered 80 percent burns when he ... Sidhi district. The counsellor had refused to advise Jaiswal ...
... and beans aren't the only foods that pack a ... start to pregnancy. ,Researchers now have used ... full day's worth of the nutrient in a single ... online edition of the journal PNAS, Proceedings of the ...
... UC Irvine researchers have combined genetic and geographic data ... history over the past decade. //They found that multiple ... of Guangdong, and they identified many of the migration ... ,By knowing where H5N1 strains develop and ...
Cached Medicine News:Health News:Major Gene Study Uncovers Secrets of Leukemia 2Health News:Major Gene Study Uncovers Secrets of Leukemia 3Health News:Scientists Genetically Engineer Tomatoes With Enhanced Folate Content 2Health News:UCI Scientists Reconstruct Migration of Avian Flu Virus 2
(Date:8/26/2014)... (NYSE: ACT ), a leading global specialty pharmaceutical ... President of Actavis, will provide an overview and update of ... 2014 in New York, NY . ... will take place on Tuesday, September 9, 2014 at 11:10 ... East 42 nd Street, New York, NY ...
(Date:8/26/2014)... , Aug. 26, 2014 Blue Bell, ... largest office worldwide. PRA, a leading global Contract Research Organization (CRO), ... Fort Washington locations into new modern Class ... new office opened this week and marks the first phase of ... for us at PRA," said Harris Koffer , President of ...
(Date:8/26/2014)... 2014   Quanta Aesthetic Lasers , the premier emerging ... , expands the offerings in their robust product portfolio with ... available for shipping to medical spas, clinics, and doctors, offices ... The QuantaShape is manufactured in the Chianti hills of ... The device was previously sold as both the VASERShape™ and ...
Breaking Medicine Technology:Actavis to Present at Morgan Stanley Global Healthcare Conference 2014 2PRA Health Sciences Expands in Pennsylvania 2Another Italian Beauty Joins the Quanta Aesthetic Lasers Lineup 2
... 2011 Milestone Scientific Inc. (Pink Sheets: ... injection systems for medical and dental markets, today announced ... OTCQB(TM) electronic quotation and trading system under the ticker ... action as a result of the addition of the ...
... Texas, March 14, 2011 (Nasdaq: VRML ... inclusion of OVA1® as part of the recently published ... Obstetrics and Gynecology , the American College of Obstetricians ... published an update committee opinion on the role of ...
Cached Medicine Technology:Milestone Scientific Inc. Commences Trading on the OTC Pink 2OVA1 Included in Latest ACOG/SGO Committee Opinion 2OVA1 Included in Latest ACOG/SGO Committee Opinion 3OVA1 Included in Latest ACOG/SGO Committee Opinion 4
...
1.7% Tryptone, 0.3% Soytone, 0.5% Sodium Chloride, 0.25% Dextrose, 0.25% Potassium Phosphate....
... The basic Thermomixer is a compact model ... 24 x 1.5 ml tubes. Impressive features ... clear design, and high stabilityeven at maximum ... for gentle to vigorous mixing, including intermittent ...
... Penicillin/25,000 ug Streptomycin All ... and Buffer products are ... cGMP regulations and are ... assure compatibility. , Typical ...
Medicine Products: