Navigation Links
Largest ever analysis of DES data demonstrates safety, efficacy in on-and-off-label use
Date:3/27/2008

CHICAGO, IL MARCH 27, 2008 The Cardiovascular Research Foundation (CRF) will present results of the largest meta-analysis to date comparing mortality rates for drug-eluting stents (DES) versus bare metal stents (BMS) at the Drug-Eluting Stent Revolution VII meeting tomorrow evening in Chicago.

The analysiswhich includes approximately 180,000 patients from 52 studieswas performed by a team of researchers led by Ajay J. Kirtane, MD, Assistant Professor of Clinical Medicine and an interventional cardiologist at NewYork-Presbyterian Hospital/Columbia University Medical Center, and Gregg W. Stone, MD, Chairman of CRF and Professor of Medicine at Columbia University Medical Center and Director of Cardiovascular Research and Education at the Center for Interventional Vascular Therapy at NewYork-Presbyterian Hospital.

Drs. Kirtane and Stone conducted two parallel meta-analyses examining DES vs. BMS use in both randomized, controlled trials and in observational registry analyses. The overall analysis represents the largest systematic overview of real-world (comprising both on-label and off-label) DES use to date and incorporates an updated overview of both the published literature as well as the most recent data from several unpublished studies presented in the last year.

The findings from these parallel studies are striking, said Dr. Stone.

The meta-analysis of 22 randomized trials included more than 9000 patients with recent follow-up from previously published trials. According to the results, DES resulted in small non-significant reductions in death and MI, with a greater than 50% decrease in subsequent TVR procedures, said Dr. Stone, adding that these findings are consistent with both on-label and off-label use of DES.

And in the 30-study registry meta-analysis (involving more than 170,000 real-world patients), DES resulted in significant 20% and 11% reductions in death and MI, respectively, with a similar reduction
'/>"/>

Contact: Irma Damhuis
idamhuis@crf.org
212-851-9187
Cardiovascular Research Foundation
Source:Eurekalert

Page: 1 2

Related medicine news :

1. An invitation to Europes largest forum on breast cancer
2. Spartan Stores Becomes Largest U.S. Supermarket Chain to Receive NSF Shop Fresh(TM) Certification
3. CVS, Americas Largest Pharmacy Chain, Pays Nearly $37 Million to Settle Federal and State Generic Drug Switching Charges
4. Grassini & Wrinkle Law Firm Are Awarded Largest PI Verdict in Ventura County History
5. Medco Breaks Ground For Worlds Largest Automated Pharmacy
6. Cardiac Science Delivers Largest Order of Electrocardiograph Systems in Company History
7. AMSA Annual Convention: Largest Gathering of Medical Students Celebrates 58 Years of Student Activism
8. McGraw-Hill Professional Enters Partnership with American College of Physicians, the Worlds Largest Internal Medicine Organization
9. Netsmart Technologies Acquires Largest Provider of Software for Private Practice Mental Health Providers and Therapists
10. Crdentia Selected by Leading Staffing Vendor to Provide Health Care Staffing Services to One of the Largest Hospital Chains in the U.S.
11. $30.3 Million Jury Verdict Believed to Be New Jerseys Largest
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... (HealthDay News) -- Unlike children, the vast majority of adults ... at mealtime, according to a new study. This ... not just Americans, researchers from Cornell University revealed. They ... or improve their eating habits make better choices. "If ... stomach," researcher Brian Wansink, director of the Cornell Food ...
(Date:7/25/2014)... 2014 (HealthDay News) -- Although cervical cancers are declining ... to human papillomavirus (HPV) are increasing, a new study ... base of the tongue and tonsils have increased over ... younger than 45, the Canadian researchers report. "The ... younger men and of anal cancer among younger women ...
(Date:7/25/2014)... that controls when genes are switched on or off ... brain to regulate metabolism, UT Southwestern Medical Center researchers ... therapies to treat obesity and diabetes, since the transcription ... appears to influence the body,s sensitivity to insulin ... to the body,s regulation of food intake and sugar ...
(Date:7/25/2014)... NH (PRWEB) July 25, 2014 Innerspire, ... has joined the company as a Creative Enrollment Specialist. ... extensive relationship building skills as well as his accomplished ... of small business clients, and to service the creative ... Additionally, Greg will work with small business owners ...
(Date:7/25/2014)... American Brain Tumor Association (ABTA) today unveiled branding of ... patient and family conference in Chicago. , “This is ... we – the first and now only national organization ... tumor research – extend our reach by engaging volunteers ... our materials and services into the hands of those ...
Breaking Medicine News(10 mins):Health News:Most Adults Are Members of 'Clean Plate Club' 2Health News:Anal, Throat Cancers on the Rise Among Young Adults, Study Finds 2Health News:Manipulating key protein in the brain holds potential against obesity and diabetes 2Health News:Innerspire, LLC Continues National Expansion 2Health News:Innerspire, LLC Continues National Expansion 3Health News:Innerspire, LLC Continues National Expansion 4Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 2Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 3
... Include 24-oz and Convenient 4-oz Travel Size Spray ... PURE ) today announced an agreement ... silver dihydrogen citrate (SDC)-based disinfectant as OneShot Plus(TM) ... Plus product line. OneShot Plus DD eliminates ...
... retire from BoardNATICK, Mass., March 2 Boston Scientific Corporation ... Board of Directors has elected John E. Sununu as a ... as a U.S. Senator from New Hampshire. He was ... Foreign Relations, and he was appointed the Congressional Representative to ...
... no harm -- from TV viewing by young children, , , MONDAY, ... a shelf full of videos claiming to be educationally stimulating for ... wallet. , A new study suggests that watching television won,t ... several hours a day. , "TV, in and of itself, ...
... Officially Launched to Provide Consumers a Free-of-Charge ... from Funeral Homes, Cremation Services and Cemeteries ... http://www.FuneralDecisions.com ) has announced the official launch ... tool for individuals seeking funeral, cremation, and ...
... System Cart Allows Easier Operation and Improved Workflow ... Traxtal Inc., the pioneer and world leader in ... newly designed system cart for the PercuNav interventional ... Booth # 322 of the Society of Interventional ...
... March 2 /PRNewswire-FirstCall/ - Bioniche Life Sciences Inc. ... today announced that the Company has amended the ... facility with Valens U.S. (formerly Laurus Master Funds). ... agreed to a near-term extension of this facility, ...
Cached Medicine News:Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 2Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 3Health News:Sterifide Laboratories to Launch 'Powered by SDC' OneShot Plus Disinfectant and Deodorizer 4Health News:Boston Scientific Announces Election Of John Sununu To Its Board Of Directors 2Health News:Boston Scientific Announces Election Of John Sununu To Its Board Of Directors 3Health News:Boston Scientific Announces Election Of John Sununu To Its Board Of Directors 4Health News:TV Watching Doesn't Fast-Track Baby's Skills 2Health News:TV Watching Doesn't Fast-Track Baby's Skills 3Health News:Taking the Stress Out of Funeral Planning, FuneralDecisions.com Offers Consumers an Innovative Approach 2Health News:Traxtal to Introduce Next-Generation PercuNav System Cart at SIR Annual Scientific Meeting 2Health News:Bioniche Revolving Credit Facility Maturity Date Amended 2
(Date:7/25/2014)... R.I. , July 25, 2014  CVS Caremark ... a conference call on Tuesday, August 5, 2014, at ... its second quarter 2014 financial results. An ... simultaneously through the Investor Relations portion of the CVS ... webcast, visit http://info.cvscaremark.com/investors . This webcast will be ...
(Date:7/25/2014)... Cardinal Health will today name three of ... its prestigious Independent Pharmacy Best Practices Competition, during the ... nation,s largest gatherings of independent pharmacists. ... Ohio , Tennessee ... selected for implementing exceptionally creative methods that demonstrate how ...
(Date:7/25/2014)... York , July 25, 2014 ... Transparency Market Research "Global and China Insulin Market (Rapid-Acting, ... Industry Analysis, Size, Share, Growth, Trends and Forecast (Value ... was valued at USD 19.99 billion in 2012 and ... from 2013 to 2019 to reach USD 32.24 billion ...
Breaking Medicine Technology:Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 2Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 3Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 4Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 5Cardinal Health Announces Three Best Practice Winners for Leading Change in Community Pharmacy 6Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 2Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 3Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 4
... The Clariflex® Intraocular Lens is indicated ... years of age or older in whom ... IOL is a third-generation IOL design made ... is designed both to reduce internal reflections ...
... Chamber Lenses: The Bausch & Lomb PMMA Posterior ... for primary implantation for the visual correction of ... older where a cataractous lens has been removed ... to be placed in the ciliary sulcus or ...
... All USIOL lenses are manufactured ... and processes. Perspex CQ UV ... the multi-piece and single piece ... available in both nonphaco and ...
... sterile nonpyrogenic, transparent viscoelastic solution of highly ... mg/ml of high molecular weight (greater than ... physiological saline. In the limit of zero ... (105 Pa s) at 25 C and ...
Medicine Products: