Navigation Links
Larger skin lesions appear more likely to be melanomas
Date:4/21/2008

Skin lesions larger than 6 millimeters in diameter appear more likely to be melanomas than smaller lesions, according to a report in the April issue of Archives of Dermatology, one of the JAMA/Archives journals. The findings suggest that the diameter guidelines currently used by dermatologists to screen for melanoma are useful.

Many clinicians use the ABCDE method to screen for melanoma, according to background information in the article. The criteria are evidence-based guidelines that remind physicians of the features characteristic of melanomaasymmetry, border irregularity, color variegation, diameter larger than 6 millimeters and evolution, or changes in the lesion. However, some researchers argue that strict adherence to the diameter guideline will cause physicians to miss smaller melanomas.

Naheed R. Abbasi, M.P.H., M.D., of the New York University School of Medicine, New York, and colleagues studied 1,323 patients undergoing biopsies of 1,657 pigmented skin lesions or markings suggestive of melanoma. The maximum diameter of each lesion was calculated before biopsy using a computerized skin imaging system.

Of the lesions, 804 (48.5 percent) were larger than 6 millimeters in diameter and 138 (8.3 percent) were diagnosed as melanoma. Invasive melanoma, which has penetrated deeper into the skin, was diagnosed in 13 of 853 lesions (1.5 percent) that were 6 millimeters or smaller in diameter and in 41 of 804 (5.1 percent) lesions that were larger than 6 millimeters in diameter. In situ melanomas, which remain in the skins outer layers, were diagnosed in 22 of 853 (2.6 percent) lesions 6 millimeters or smaller in diameter and in 62 of 804 (7.7 percent) lesions larger than 6 millimeters in diameter.

Within each 1-millimeter diameter range from 2.01 to 6 millimeters, the proportion of melanomas did not vary significantly, remaining stable at 3.6 percent to 4.5 percent, the authors write. However, we observed a nearly 100-percent increase in the proportion of melanomas when comparing the 5.01- to 6-millimeter category (4.3 percent) to the 6.01- to 7-millimeter category (8.3 percent).

We recommend that a diameter criterion of larger than 6 millimeters remain a part of the ABCDE criteria, the authors conclude. We do not recommend downward revision of the D criterion at this time. In the United States, rates of melanoma and nonmelanoma skin cancers have markedly increased, and skin biopsy rates have more than doubled in 20 years. In an era that demands greater data to support clinical decision making, the ABCDE criteria are valuable evidence-based guidelines to aid physicians in decisions regarding the biopsy of pigmented lesions of the skin.


'/>"/>

Contact: Pamela McDonnell
212-404-3555
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. VIDEO from Medialink and Siemens: Pinpointing Prostate Cancer in Larger Patients
2. University of Detroit Mercy School of Dentistry Moves to Larger Facility on New Corktown Campus
3. Washington Dental Service Opens Larger Spokane Office
4. Patients with larger social networks may fare better after an operation
5. Significant Growth for Pinstripe Leads to Need for Larger Facility
6. When couples face the diagnosis of cancer, women carry a larger emotional burden than men
7. Kaiser Permanente Study Shows That a Larger Abdomen in Midlife Increases Risk of Dementia
8. Brain Lesions Predict MS Progression
9. Precancerous Lesions Raise Cervical Cancer Risk
10. Narrow band imaging colonoscopy identifies flat dysplastic lesions in ulcerative colitis patients
11. Devax Announces Completion of Enrollment of DIVERGE Trial of Novel Drug- Eluting Stent System for Bifurcation Lesions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... May 26, 2017 , ... Rob Lowe acts as host and helps educate ... is on hiking in American. Viewers can reconnect with America as it explores some ... , Many consumers have looked for an inventive new place for a family vacation, ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the ... Journey to the Cross” is the creation of published authors, Bob and Margaret Massey. ... to say, he is "panther quick and leather tough." His love for others is ...
(Date:5/26/2017)... ... ... “Cactus Jack: Against All Odds”: the story of Coach Cactus Jack and the ... is the creation of published author, Walter Hubbard, a retired wildlife and fisheries biologist ... Jane. Walter. Walter and Jane have three adult children and a granddaughter. ...
(Date:5/24/2017)... ... May 24, 2017 , ... In modern research, success depends ... instruments for research and understanding the basic principles that were designed to drive ... innovations in stereo microscopy for brightfield and fluorescence typically used in laboratories working ...
(Date:5/24/2017)... San Diego, California (PRWEB) , ... May 24, ... ... patient care through innovative medical image management and interpretation, has received U.S. Food ... technology. , Nucleus.io is a web-based, scalable and secure cloud platform for ...
Breaking Medicine News(10 mins):
(Date:5/11/2017)... , May 11, 2017  Thornhill Research ... has been awarded an $8,049,024 USD five-year, firm-fixed-priced, ... through the Canadian Commercial Corporation (CCC) ( ... Anesthesia Systems to administer general anesthesia to patients ... "The US Marine Corps have been ...
(Date:5/10/2017)... 10, 2017 CSSi, the global leader in ... research industry, is proud to announce the launch of ... website features both enriched content and a customized layout ... the company,s already well-established position as the top global ... "After many months of hard work, we are delighted ...
(Date:5/8/2017)... -- MACRA replaces the outdated sustainable growth rate ... Black Book Research crowdsource-surveyed 8,845 physician practices from February ... for MIPS Compliance Technology is Booming ... or more clinicians seek to buy Merit-Based Incentive Payment ... of the changes, the hunt is on for the ...
Breaking Medicine Technology: