Navigation Links
Larger Skin Lesions More Likely to Be Melanoma
Date:4/22/2008

Study backs current skin cancer-screening guidelines

TUESDAY, April 22 (HealthDay News) -- Skin lesions larger than six millimeters in diameter are more likely than smaller lesions to be melanoma skin cancer, a new study suggests.

The finding supports the current widespread use of diameter guidelines to screen for melanoma, researchers say.

This "ABCDE" screening method is based on five features characteristic of melanoma: asymmetry, border irregularity, color variegation, diameter larger than six millimeters, and changes in a lesion.

However, some experts have argued that strict adherence to the diameter guideline will cause doctors to miss smaller melanomas, according to background information in the study.

In this study, researchers at the New York University School of Medicine, New York City, studied more than 1,300 patients undergoing biopsies for 1,657 pigmented skin lesions or markings suggestive of melanoma. Of those lesions, 804 (48.5 percent) were larger than six millimeters in diameter and 138 (8.3 percent) were diagnosed as melanoma.

Invasive melanomas (which have penetrated deeper into the skin) were diagnosed in 13 of 853 lesions (1.5 percent) that were six millimeters or smaller in diameter and in 41 of the 804 (5.1 percent) of lesions that were larger than six millimeters. In situ melanomas (those that remain in the skin's outer layers) were diagnosed in 22 of the 853 (2.6 percent) of lesions six millimeters or smaller and in 62 of the 804 (7.7 percent) of lesions larger than six millimeters.

"With each one-millimeter diameter range from 2.01 to six millimeters, the proportion of melanomas did not vary significantly, remaining stable at 3.6 percent to 4.5 percent," the study authors wrote. "However, we observed a nearly 100-percent increase in the proportion of melanomas when comparing the 5.01- to six-millimeter category (4.3 percent) to the 6.01- to seven-millimeter category (8.3 percent)."

The study was published in the April issue of the journal Archives of Dermatology.

"We recommend that a diameter criterion of larger than six millimeters remain a part of the ABCDE criteria," the researchers concluded. "We do not recommend downward revision of the D criteria at this time. In the United States, rates of melanoma and nonmelanoma skin cancers have markedly increased, and skin biopsy rates have more than doubled in 20 years. In an era that demands greater data to support clinical decision making, the ABCDE criteria are valuable evidence-based guidelines to aid physicians in decisions regarding the biopsy of pigmented lesions of the skin."

More information

The American Academy of Dermatology has more about skin cancer.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, April 21, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Larger skin lesions appear more likely to be melanomas
2. Kaiser Permanente Study Shows That a Larger Abdomen in Midlife Increases Risk of Dementia
3. When couples face the diagnosis of cancer, women carry a larger emotional burden than men
4. Significant Growth for Pinstripe Leads to Need for Larger Facility
5. Patients with larger social networks may fare better after an operation
6. Washington Dental Service Opens Larger Spokane Office
7. University of Detroit Mercy School of Dentistry Moves to Larger Facility on New Corktown Campus
8. VIDEO from Medialink and Siemens: Pinpointing Prostate Cancer in Larger Patients
9. Mammography plus sonography can help rule out breast cancer in patients with palpable lesions
10. Topical Cream Treats Precancerous Lesions of Vulva
11. Small Brain Lesions More Common Than Thought in Those Over 60
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in ... in honor of the city’s history as home to some of the world’s leading ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... ... , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize ... Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into ... Simply select a ProHand generator and drag it above media or text in the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical ... the "Company"), which develops, markets and sells medical devices ... , signed a strategic cooperation agreement with Hongyuan ... "Hongyuan Supply Chain") on June 20, 2016, to develop ... the strategic cooperation agreement, Dehaier will leverage Hongyuan Supply ...
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
Breaking Medicine Technology: