Navigation Links
Large weight gain raises risk for recurrence among breast cancer survivors
Date:4/5/2011

Oakland, Calif., April 5, 2011 Breast cancer survivors who experience large weight gain have an increased risk of death after diagnosis, according to research scientists at the Kaiser Permanente Division of Research in Oakland, Calif.

Breast cancer survivors who experienced large weight gain (10 percent or more over their pre-diagnosis weight) were 14 percent more likely to experience a cancer recurrence compared to women whose weight remained stable (within 5 percent of pre-diagnosis weight) following diagnosis.

The study results are being presented at the American Association of Cancer Research 102nd meeting, to be held April 2-6 in Orlando, Fla.

"Most women are not gaining a large amount of weight following breast cancer diagnosis," said lead researcher Bette Caan, DrPH, a senior research scientist at the Kaiser Permanente Division of Research. "However, our analysis showed an association with poorer outcomes overall for those who do." She explained that moderate weight gain did not affect breast cancer outcomes.

"Women tend to worry about gaining weight after a breast cancer diagnosis," said Caan. "But it's actually only the larger weight gains that increase the risk of poor outcomes."

Researchers also found that women who have large weight gains after diagnosis tend to be within normal weight ranges to begin with. In addition, the post-diagnosis effect of the weight gain tends to be greater for women who were originally thinner, they explained.

Women who were leaner to begin with at diagnosis (body mass index less than 25) and who later gained 10 percent or more, had a 25 percent higher risk of cancer death and also had a higher risk of recurrence compared to women whose weight remained stable (within 5 percent of pre-diagnosis weight) following diagnosis.

Large weight gain occurred in 16 percent of women overall. Just over 19 percent of women with a BMI less than 25 fell into the large weight gain category, but only 11.1 percent of women with a BMI greater than 30 fell into that category.

Data for the study came from the After Breast Cancer Pooling Project, which includes 18,336 breast cancer survivors from four prospective cohorts three in the United States and one in Shanghai.

Caan explained that more research is needed to identify those women most at risk for extreme weight gain and those whose weight gain puts them at risk for poor cancer outcomes.


'/>"/>

Contact: Danielle Cass
danielle.x.cass@kp.org
510-267-5354
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. EdenHome.com Adds Aventura Organic Clothes to Site and Announces Largest Online Selection of Stylish Organic Clothes for Men, Women and Children
2. Psychologists Say New Jerseys Largest Health Plan Violates Patient Privacy, Restricts Access to Care and Wastes Taxpayer Money
3. Confronting infectious disease threats at large-scale international events
4. New clues found linking larger animals to colder climates
5. George Lundberg, MD, Joins MedPage Today(R) as Editor-at-Large
6. Combination therapy more effective for enlarged prostate
7. HealthcareSource Announces New Client Wins: Strong Sales Momentum Driven by Regional and Large Health Systems
8. Biocell Center Corporation Partners with New Englands Largest Community-Based Hospital Network to Offer a Unique Service in Amniotic Fluid Stem Cell Preservation
9. DTM Systems Corporation Ranked Number One as the Largest Reseller in British Columbia to Hewlett Packard Canada
10. Historic Agreement Reached to Transition Illinois Residents Unnecessarily Housed in Large, Impersonal Nursing Homes
11. Fewer Deaths in Larger, Busier Hospitals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s ... June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... helping service members that have been wounded in battle and their families. Venture Construction ...
(Date:6/24/2016)... TN (PRWEB) , ... June 24, 2016 , ... ... population health management skills and infrastructure. Most providers, however, are unsure how to ... Population Health Ascend to define a path forward tailored to an organization’s ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Seema Daulat, a native Texan and University ... Lamar location as of July 13, 2016. , Dr. Daulat earned her Doctorate of ... she regularly volunteered at the Agape Clinic serving Dallas’ underprivileged community. , Following medical ...
(Date:6/23/2016)... ... , ... The Mechille Wilson Agency, a Texas-based insurance company that provides coverage ... is initiating a charity drive to assist a student to be chosen from the ... that will be presented to the chosen student to help with the growing costs ...
(Date:6/23/2016)... ... June 23, 2016 , ... The annual Blue Ribbon ... of Parkinson’s Disease and Movement Disorders. This special session provides a critical review ... novelty, and quality of both clinical and basic research presented by delegates. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... Oticon , industry leaders in advanced ... launch of Oticon Opn ™, the world,s first ... of possibilities for IoT devices.      (Photo: ... Oticon introduces a number of ,world firsts,: ...
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
(Date:6/23/2016)... 2016  Experian Health, the healthcare industry ... patient payment and care experience, today announced ... and services that will enhance the breadth ... These award-winning solutions will enable healthcare professionals ... in an ever-changing environment and redefine front-office ...
Breaking Medicine Technology: