Navigation Links
Large intensive care study reveals vital recommendations for treatment of brain injury patients
Date:9/4/2007

A landmark Australian and New Zealand intensive care study has provided vital information for the treatment of patients with brain injuries. The results of the SAFE-TBI Study, published today in the New England Journal of Medicine, confirm that the choice of resuscitation fluids affects the chances of patients with brain injury surviving.

Study leader Professor John Myburgh, from the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG)and The George Institute for International Health explains, Patients with brain injury require resuscitation fluids to promptly restore blood flow to the brain following trauma. Until now,clinicians were uncertain which fluid to use in this situation and there was wide variation in the types of fluids used in these patients. Our study confirmed that patients resuscitated with albumin-based fluidsimmediately following brain injury, had a higher death rate than those who received saline.

In 2004, researchers from the ANZICS CTG, The George Institute for International Health and the Australian Red Cross Blood Service published the largest study ever performed in intensive care in the New England Journal of Medicine. The study, called the SAFE Study, was prompted by earlier reports from the United Kingdom, which suggested that the administration of albumin-based fluids used for the resuscitation of critically ill patients was associated with a higher rate of death. The SAFE Study, which studied almost 7000 patients in Australia and New Zealand, concluded that the death rate was the same when patients were given either albumin-based or saline-based fluids. However, a higher death rate was seen in those patients who had brain injuries due to trauma, caused by road traffic crashes or falls, and who received albumin-based fluids.

Given the importance of these results, the SAFE Study researchers conducted a detailed analysis of the patients with brain injuries (the SAFE-TBI Study) that included determining the death rate two years after the original injury as well as an assessment of the level of disability in those who survived.

Professor Myburgh said, Our study provides compelling new data to guide clinicians in the choice of resuscitation fluids in patients with traumatic brain injury. These results will have a major impact on clinical practice guidelines for resuscitation of these patients.

The SAFE-TBI Study also raises an important public health issue for millions of patients with brain injuries worldwide. Given that traumatic brain injury results in considerable death and disability in all societies, but particularly in the developing world where trauma rates are increasing, it is important for doctors to know that a patients chances of survival can be substantially improved by the administration of a readily available and inexpensive fluid such as saline, Professor Myburgh added.


'/>"/>

Contact: Janet Hall
janethall@bigpond.com
61-411-187-808
Research Australia
Source:Eurekalert

Related medicine news :

1. Tobacco and alcohol connected to larger health problems
2. New technique for heart enlargement
3. Just standing next to a large person can be bad for ones image
4. 3 die, 500 sickened in nations largest hepatitis A outbreak Associated Press
5. Two drugs Mays Be Better Than One For Prostate Enlargement
6. Risks Of An Enlarged Heart
7. The Link Between Larger Birth Weight And Cancer Risk
8. Enlarged waistline may predict atherogenesis for postmenopausal women
9. Worlds Largest Cord Blood Bank to be started in India
10. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
11. Fear Of Dengue Epidemic Looms Large: Fever Kills Five in Pakistan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... 24, 2017 , ... Myers Jackson is well known for auctioning homes that ... homes anywhere on the planet. The luxury home market is alive and well and ... A quick search of “11 Spyglass Hill Auction will enlighten you on the dynamics ...
(Date:5/24/2017)... ... May 24, 2017 , ... Medic CE , a Career Step company, ... Septic Shock” hosted by the Journal of Emergency Medical Services (JEMS). The free webinar, ... be presented by Captain Rommie Duckworth, LP, a career fire captain as well as ...
(Date:5/24/2017)... ... May 24, 2017 , ... Adelberg-Montalvan ... dentistry options for its patients on Long Island, New York. , Holistic ... being, and is one of the biggest trends in dentistry today. , ...
(Date:5/24/2017)... ... 24, 2017 , ... Fiberstar, Inc., http://www.FiberstarIngredients.com a ... beverage industry offers Citri-Fi®, a natural citrus fiber, to improve beverage ingredient declarations. ... a result, labels need to deliver simple, transparent and clear messaging. Listed food ...
(Date:5/23/2017)... ... May 23, 2017 , ... ... Clinical Integration company, announced today that its iClinic V12.2 solution has achieved approval ... NCQA recently introduced PCMH 2017 standards which emphasize team-based care with a ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... , May 10, 2017 Global Health Intelligence ... Latin America , published its 2017 ranking of ... is based on extensive data analysis from GHI,s hospitals ... hospitals database for the region. The GHI database covers 86% ... offering more than 130 data points for each institution in ...
(Date:5/9/2017)... 2017 Zimmer Biomet Holdings, Inc. (NYSE and ... announced it has earned a spot on Forbes, ... Company was ranked among 500 U.S. employers as well ... Equipment and Services. The annual Forbes ... independent survey of over 30,000 employees across 25 industries. ...
(Date:5/8/2017)... , May 8, 2017 MACRA replaces ... from fee for service reimbursement. Black Book Research crowdsource-surveyed ... 1.       The Market for MIPS Compliance Technology ... of physician practices with 3 or more clinicians seek ... by Q4. "Given the magnitude of the changes, the ...
Breaking Medicine Technology: