Navigation Links
Large intensive care study reveals vital recommendations for treatment of brain injury patients
Date:9/4/2007

A landmark Australian and New Zealand intensive care study has provided vital information for the treatment of patients with brain injuries. The results of the SAFE-TBI Study, published today in the New England Journal of Medicine, confirm that the choice of resuscitation fluids affects the chances of patients with brain injury surviving.

Study leader Professor John Myburgh, from the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG)and The George Institute for International Health explains, Patients with brain injury require resuscitation fluids to promptly restore blood flow to the brain following trauma. Until now,clinicians were uncertain which fluid to use in this situation and there was wide variation in the types of fluids used in these patients. Our study confirmed that patients resuscitated with albumin-based fluidsimmediately following brain injury, had a higher death rate than those who received saline.

In 2004, researchers from the ANZICS CTG, The George Institute for International Health and the Australian Red Cross Blood Service published the largest study ever performed in intensive care in the New England Journal of Medicine. The study, called the SAFE Study, was prompted by earlier reports from the United Kingdom, which suggested that the administration of albumin-based fluids used for the resuscitation of critically ill patients was associated with a higher rate of death. The SAFE Study, which studied almost 7000 patients in Australia and New Zealand, concluded that the death rate was the same when patients were given either albumin-based or saline-based fluids. However, a higher death rate was seen in those patients who had brain injuries due to trauma, caused by road traffic crashes or falls, and who received albumin-based fluids.

Given the importance of these results, the SAFE Study researchers conducted a detailed analysis of the patients with brain injuries (the SAFE-TBI Study) that included determining the death rate two years after the original injury as well as an assessment of the level of disability in those who survived.

Professor Myburgh said, Our study provides compelling new data to guide clinicians in the choice of resuscitation fluids in patients with traumatic brain injury. These results will have a major impact on clinical practice guidelines for resuscitation of these patients.

The SAFE-TBI Study also raises an important public health issue for millions of patients with brain injuries worldwide. Given that traumatic brain injury results in considerable death and disability in all societies, but particularly in the developing world where trauma rates are increasing, it is important for doctors to know that a patients chances of survival can be substantially improved by the administration of a readily available and inexpensive fluid such as saline, Professor Myburgh added.


'/>"/>

Contact: Janet Hall
janethall@bigpond.com
61-411-187-808
Research Australia
Source:Eurekalert

Related medicine news :

1. Tobacco and alcohol connected to larger health problems
2. New technique for heart enlargement
3. Just standing next to a large person can be bad for ones image
4. 3 die, 500 sickened in nations largest hepatitis A outbreak Associated Press
5. Two drugs Mays Be Better Than One For Prostate Enlargement
6. Risks Of An Enlarged Heart
7. The Link Between Larger Birth Weight And Cancer Risk
8. Enlarged waistline may predict atherogenesis for postmenopausal women
9. Worlds Largest Cord Blood Bank to be started in India
10. India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu
11. Fear Of Dengue Epidemic Looms Large: Fever Kills Five in Pakistan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... ... January 23, 2017 , ... The Masters of Science ... evaluation leaders with decades of experience who remain current practitioners in the field. ... system, there is a renewed demand for versatile, data-driven leadership.The American University’s MS ...
(Date:1/23/2017)... ... January 23, 2017 , ... Moisture measurement is a ... method is paramount to success. Selecting an inappropriate measurement method can cause costly ... use the same equipment. Rare or expensive substances are wasted and production may ...
(Date:1/23/2017)... ... January 23, 2017 , ... Gynecology Associates of ... gynecological services for women of all ages. The staff of Gynecology ... of reproductive services from routine health screenings to diagnosing and treating female concerns ...
(Date:1/23/2017)... ... ... “Some Infallible Characteristics of Christ”: a fascinating and entrancing novel exploring the ... of published author, Rev. Dr. Robert W. Thomas, the third of seven siblings. He ... nineteen, a pastor for over fifteen years. He is a graduate of N.C. College ...
(Date:1/22/2017)... ... January 22, 2017 , ... Medical lab testing through hospitals and ... a simple test will take days to arrive to the end customer, having to ... access to their lab tests, bypassing the cost and delay of traditional means. Now ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... Jan 23, 2017 Research and Markets has announced ... Trends - Product - Forecast to 2025" report to their offering. ... Report Highlights: ... market trends to identify the investment opportunities Market forecasts ... Key market trends across the business segments, Regions and Countries ...
(Date:1/23/2017)... Jan. 23, 2017  Using Astute Medical,s ... risk for acute kidney injury (AKI) after open-heart ... care guidelines significantly improved outcomes by ... more than 33 percent, according to a ... Intensive Care Medicine. Experience ...
(Date:1/23/2017)... January 23, 2017 Ahead of today,s trading ... how they have fared at the close: Kite Pharma Inc. (NASDAQ: ... OVAS ), and Regeneron Pharmaceuticals Inc. (NASDAQ: ... were relative laggards on Friday, January 20 th , 2017, down ... research reports on these stocks now at: ...
Breaking Medicine Technology: