Navigation Links
Landmark Study Published in New England Journal of Medicine
Date:6/9/2009

New York Hospital Queens One of Clinical Sites, Research Director is Co-Author

FLUSHING, N.Y., June 9 /PRNewswire/ -- One of the world's most respected medical journals, the New England Journal of Medicine, is publishing a landmark study this week that explores treatments for people with both Type 2 diabetes and coronary artery disease. The Lang Research and Education Center of New York Hospital Queens was one of the sites that conducted this study.

The study, known as BARI 2D, (Bypass Angioplasty Revascularization Investigation 2 Diabetes) was also presented yesterday in New Orleans at the American Diabetes Association 69th Scientific Sessions -- a national medical conference. The results demonstrated that there is no difference in mortality among patients with type 2 diabetes and stable heart disease who received prompt bypass surgery or angioplasty compared to drug therapy alone. The results also showed that while prompt bypass in patients with more severe heart disease did not lower mortality, it lowered their risk of subsequent major cardiac events.

Phyllis August, M.D., M.P.H., director, Lang Research Center for Research and Education, New York Hospital Queens, served as a co-investigator and co-author of the study. She called the results, "very exciting and good news." "More than 20 million Americans suffer from type 2 diabetes and many of these people also have heart disease. This deadly disease duo is affecting more and more people at increasingly younger ages."

According to Dr. August, the message to patients is a strong one; "you can modify this disease with careful attention to prevention, managing risk factors and by following your doctor's instructions."

"The study's results provide needed guidance about which approaches can best help these patients," said August. They also indicate that when a patient with type 2 diabetes has more severe heart disease it may be better to do bypass surgery early than to wait and simply treat with medication. For patients with milder disease who are candidates for angioplasty, it is appropriate to treat with drug therapy first."

Background

The BARI 2D study began recruiting patients in 2001. The results are based on 2,368 patients with both type 2 diabetes and stable heart disease who were under a physician's care to control their cholesterol and blood pressure. Patients were randomized to receive drug therapy plus undergo prompt revascularization to restore blood flow -- either angioplasty to open blocked arteries or bypass surger -- ?or to receive drug therapy alone. The investigators also looked at which of two diabetes drug treatment strategies resulted in better outcomes -- insulin-providing (increasing the amount of insulin) or insulin-sensitizing (lowering the body's resistance to its own insulin, such as metformin or rosiglitazone). The study was not a comparison between angioplasty and bypass surgery, but rather a comparison between a prompt procedure and medical therapy alone.

The results show that five-year survival rates did not differ significantly between the revascularization group (88.3 percent) and the drug therapy group (87.8 percent). In addition, there was no significant difference in survival between those who received insulin-providing drugs (87.9 percent) and those who received insulin-sensitizing drugs (88.2 percent). However, in the group that received bypass surgery, the rate of all major cardiovascular events (heart attacks, strokes and death) was significantly lower (22.4 percent) compared to those who received drug therapy alone (30.5 percent). This benefit appeared to be greatest in those who underwent bypass and received insulin-sensitizing drugs.

BARI 2D was coordinated by the Epidemiology Data Center at the University of Pittsburgh Graduate School of Public Health and involved 49 clinical sites in the United States and abroad, including The Lang Research and Education Center of New York Hospital Queens, Flushing Queens. Major funders of the study include the National Heart, Lung and Blood Institute, the National Institute of Diabetes and Digestive and Kidney Diseases and GlaxoSmithKline.

Note: Reporters interested in obtaining a copy of the Abstract and Editorial from the New England Journal of Medicine, June 11, 2009, or to interview Dr. August, who also holds a prominent position with the Weill Medical College of Cornell University, please contact Scott Sieber at 718-670-1579.

Contact: Scott Sieber, 718-670-1579


'/>"/>
SOURCE New York Hospital Queens
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. CAP Joins Landmark Lawsuit Challenging Legality of Myriad Genetics Gene Patents
2. Landmark USGS study
3. Oakwood Investment Triggers the Development of a New Landmark in Downtown East Dearborn
4. Landmark study demonstrates Gamunex improves health-related quality of life in patients with CIDP
5. Landmark NBC News Nutrition Report: There Is Indeed Little Difference Between High Fructose Corn Syrup and Table Sugar
6. In the Midst of a National Nurse Shortage Crisis ... Nurses Celebrate Landmark Legal Settlement That Will Help Ensure Fair Compensation & Bring More RNs to the Bedside
7. Innovative Plans by Major Arizona-Based Developer Sparks Landmark Energy Conservation Legislation in Multiple States to Urge Federal Action at Wall Street Journal Conference This Week with Gore, Google CEO & T. Boone Pickens
8. Patton Boggs Wins Landmark Insurance Case for Client
9. Landmark Policy Report: Many Cancers Could Be Prevented Across the Globe
10. Landmark Report: Many Cancers Could be Prevented
11. Update on Landmark Study on Single-Payer as Economic Stimulus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... 02, 2016 , ... "Pro3rd Accents Volume 2 is a set of 30 ... titles with just a few clicks of the mouse," said Christina Austin - CEO ... animations. Choose from various styles with accented animations, rigid boxes, simplistic lines, and more. ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... Scientist & Author of Type 2 Diabetes: The Owner’s Manual, http://realtimepressrelease.com/press-releases-tagged-with/daryl-wein ... Kleyne Hour Power of Water, Global Climate Change and Your Health radio program ...
(Date:11/30/2016)... ... November 30, 2016 , ... "I hate when the mixture of saliva and ... said an inventor from Bridgewater, N.J. "I thought that there had to be a ... He developed the patent-pending DEFLECTOR to prevent saliva and toothpaste from running down the ...
(Date:11/30/2016)... (PRWEB) , ... November 30, 2016 , ... ... treating injured workers have been a focus of public policymakers and system stakeholders ... Research Institute (WCRI) released its Medical Price Index for Workers’ Compensation, Eighth ...
(Date:11/30/2016)... Atlanta, Georgia (PRWEB) , ... November 30, 2016 ... ... ODS Security Solutions (ODS), a leading provider of security services based in Richmond, ... , ODS is greatly admired for providing outstanding quality security services and prides ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2016  Maxor National Pharmacy Services, LLC ("Maxor"), today announced ... ("PSI").  The combination of Texas -based Maxor ... PSI bring together both company,s clinical expertise and high-touch patient ... industry-leading specialty pharmacy. About Maxor ... , , ...
(Date:12/2/2016)... 2016 Lianluo Smart Limited (Nasdaq: ... which develops, markets and sells medical devices and ... and international markets, recently attended the ... New Progress Forum, co-hosted by the Institute of ... , Guangdong Provincial People,s Hospital and Cardiology Department ...
(Date:12/2/2016)... The concept of rare diseases and the idea that a ... been taking shape in Europe since ... related to orphan medicinal products have been emerging at both ... individually. Many member states in the EU have led the ... products, the result of which took the shape of the ...
Breaking Medicine Technology: