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Landmark Clinical Trial Shows Surgery and Stenting Equally Safe and Effective at Preventing Stroke
Date:5/26/2010

Physicians now have more options in tailoring treatments for patients at risk for stroke.

(Vocus) May 26, 2010 -- After nine years of investigation, the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST), conducted in part by University at Buffalo Neurosurgery, shows that two different procedures designed to prevent future strokes are safe and effective overall. In the trial of 2,502 participants, carotid endarterectomy (CEA), a surgical procedure considered the gold standard prevention treatment, was compared to carotid artery stenting (CAS), a newer and less invasive procedure that involves expanding a small device in the artery to widen the blocked area and capture any dislodged plaque. The trial was funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH). Results of the study appear today in the online first edition of the New England Journal of Medicine.*

The CREST trial was performed at 117 medical centers in the United States and Canada and is considered one of the largest randomized stroke trials ever conducted. University at Buffalo Neurosurgery played a key role in the investigation as a leading enroller and the designated CAS training site for more than 200 surgeons, neurosurgeons, radiologists, and cardiologists participating in the study. University at Buffalo Neurosurgery is one of the busiest neuroendovascular laboratories and one of the most experienced and successful practitioners of carotid stenting in the world.

Results of the CREST trial show that the overall safety and efficacy of the two pro
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Landmark Clinical Trial Shows Surgery and Stenting Equally Safe and Effective at Preventing Stroke
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