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Lack of Social Interaction Affects Health Outcomes of Breast Cancer --Stress from loneliness leads to increased tumor growth, Decrease breast cancer risk by increasing social interaction
Date:9/30/2009

The American Association for Cancer Research hosted a press briefing on this study on September 29 at 1:00 p.m. ET.

Philadelphia, PA (Vocus) September 30, 2009 -- Social environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, according to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

“This study uses an elegant preclinical model and shows that social isolation alters expression of genes important in mammary gland tumor growth,” said the journal’s Deputy Editor Caryn Lerman, Ph.D. “It further elucidates the molecular mechanisms linking environmental stress with breast cancer development and progression.”

These findings suggest novel targets for chemoprevention, and future studies should evaluate whether these molecular processes can be reversed by chemopreventive agents, according to Lerman, who is the Mary W. Calkins professor of psychiatry and scientific director of the Abramson Cancer Center at the University of Pennsylvania, Philadelphia.

Previous results from clinical studies have indicated that social support can improve the health outcome of patients with breast cancer. Epidemiological studies have suggested that social isolation increases the mortality risk from several chronic diseases.

Suzanne D. Conzen, M.D., associate professor in the department of medicine and the Ben May department for cancer research at the University of Chicago, along with colleagues from the Institute of Mind and Biology at the University of Chicago, evaluated whether an unfavora
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Lack of Social Interaction Affects Health Outcomes of Breast Cancer --Stress from loneliness leads to increased tumor growth, Decrease breast cancer risk by increasing social interaction
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