Navigation Links
Lab-engineered muscle implants restore function in animals
Date:7/16/2012

WINSTON-SALEM, N.C. July 16, 2012 New research shows that exercise is a key step in building a muscle-like implant in the lab with the potential to repair muscle damage from injury or disease. In mice, these implants successfully prompt the regeneration and repair of damaged or lost muscle tissue, resulting in significant functional improvement.

"While the body has a capacity to repair small defects in skeletal muscle, the only option for larger defects is to surgically move muscle from one part of the body to another. This is like robbing Peter to pay Paul," said George Christ, Ph.D., a professor at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine. "Rather than moving existing muscle, our aim is to help the body grow new muscle."

In the current issue of Tissue Engineering Part A, Christ and team build on their prior work and report their second round of experiments showing that placing cells derived from muscle tissue on a strip of biocompatible material and then "exercising" the strip in the lab results in a muscle-like implant that can prompt muscle regeneration and significant functional recovery. The researchers hope the treatment can one day help patients with muscle defects ranging from cleft lip and palate to those caused by traumatic injuries or surgery.

For the study, small samples of muscle tissue from rats and mice were processed to extract cells, which were then multiplied in the lab. The cells, at a rate of 1 million per square centimeter, were placed onto strips of a natural biological material. The material, derived from pig bladder with all cells removed, is known to be compatible with the body.

Next, the strips were placed in a computer-controlled device that slowly expands and contracts essentially "educating" the implants on how to perform in the body. This cyclic stretching and relaxation occurred three times per minute for the first five minutes of each hour for
'/>"/>

Contact: Karen Richardson
krchrdsn@wakehealth.edu
336-716-4453
Wake Forest Baptist Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Strong communication between brain and muscle requires both having the protein LRP4
2. Heuer M.D. Research Announces CardiaShred™ - First Medical Doctor Formulated, Heart Healthy Weight Loss, Energy and Lean Muscle Building Supplement
3. Muscle Mass Linked to Bone Health in Some Parts of Body
4. Experimental drug improves muscle strength among male cancer patients
5. Mayo Clinic study links healthy muscle mass to healthy bones, finds differences by gender
6. Accelerated chemotherapy given before surgery benefits patients with muscle-invasive bladder cancer
7. Soy-based S-equol supplement reduces hot flash frequency, muscle & joint pain in US women
8. Few Patients Should Get Metal-on-Metal Hip Implants, FDA Panel Says
9. Suffering of Thousands Prompts FDA Hearing about Hip Implants
10. FDA Probing Safety of Metal-on-Metal Hip Implants
11. US Drug Watchdog Now Offers Victims of All Metal Hip Implant Failure the Names of the Best Attorneys & Calls Metal Hip Implants a Train Wreck with Up to 500,000 Victims
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2013)... May 18, 2013 Assisted living ... comes to safety and comfort of their residents. ... provides clients with an effective and cost-efficient solution ... is an integrated, turnkey communications solution that helps ... allowing residents independence and privacy. , The ...
(Date:5/18/2013)... (PRWEB) May 18, 2013 Today, ... insurance agents’ role in Marketplaces . Zane ... traditional employer sponsored health benefits, is the leader ... and health reimbursement arrangements . , According ... and Human Services (HHS) recently released a much-anticipated ...
(Date:5/18/2013)... FL (PRWEB) May 18, 2013 The ... to the special places we call home. These are the ... maps. They are the locations where the people are friendly ... show takes viewers off the highways and shares the best ... of both nations with an American sports and film celebrity. ...
(Date:5/18/2013)... “World Healthcare IT Market: Trends & Forecast (2010 – ... and opportunities in North America, Europe, Asia, & Rest ... 89 market data tables , 20 ... , http://www.marketsandmarkets.com/Market-Reports/healthcare-information-technology-market-136.html , Early buyers will ... IT market is expected to grow from $99.6 billion ...
(Date:5/18/2013)... 2013 TheBeautyPlace.com answers important questions about ... is not a result of stress, nutrient deficiency or ... Magazine, 70% of men suffer from male patterned baldness. ... renowned for hair transplant surgery, but additionally carries a ... known as Bosley Professional Strength. Their product line is ...
Breaking Medicine News(10 mins):Health News:VisionLink Nurse Call System's New Features Serve the Unique Needs of Retirement Communities 2Health News:VisionLink Nurse Call System's New Features Serve the Unique Needs of Retirement Communities 3Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 2Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 3Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 4Health News:Communities of Distinction TV Presents "A Place to Call Home" Segment 2Health News:Healthcare IT Market to reach US$ 162.2 Billion by 2015 at a CAGR of 10.2% - New Report by MarketandMarkets 2Health News:Healthcare IT Market to reach US$ 162.2 Billion by 2015 at a CAGR of 10.2% - New Report by MarketandMarkets 3Health News:TheBeautyPlace.com Features the Two New Best-Selling Hairloss Products: Bosley Professional Strength and Nioxin Systems 2Health News:TheBeautyPlace.com Features the Two New Best-Selling Hairloss Products: Bosley Professional Strength and Nioxin Systems 3
... The Cosmetic Bootcamp LLC, the leading training ... is pleased to announced reduced tuition scholarships for ... resident in dermatology, plastic surgery, ophthalmology, oculoplastic surgery, ... economic conditions, the sponsors for the meeting have ...
... for millionsBIRMINGHAM, Ala., April 28 As many as 17.8 ... 2050 and 1.57 million will be blind from the disease, ... However, a new medical study by a group of ... University of Alabama Birmingham (UAB) indicates that with ...
... Md. (April 24, 2009) The Henry M. Jackson Foundation ... a one-of-a-kind publication intended to educate anesthesiology residents in ... techniques and acute pain medicine. Its aim is to ... combat trauma. , " The Military Advanced Regional ...
... Hill-Rom Holdings, Inc., (NYSE: HRC ) invites ... president and chief executive officer, Hill-Rom. He will be ... New York City on Wednesday, May 13, 2009 at 2 ... via the internet link at http://ir.hill-rom.com/events.cfm ...
... BMP,Sunstone Corporation (Nasdaq: BJGP ) ("BMP Sunstone" ... Baledge to its board of directors following,the Company,s annual ... Mr. Baledge has over two decades ... Mr. Baledge served as Executive Vice President and General,Counsel ...
... Annual Meeting , CHICAGO, April 28 Endo Pharmaceuticals ... clinical trial data in men with hypogonadism who were ... 750 mg) injection, a long-acting testosterone replacement therapy in ... Results showed that average testosterone levels were maintained within ...
Cached Medicine News:Health News:New Medical Study Establishes First-Ever Long-Term Benefits for Macular Degeneration Sufferers Using Macular Health Vitamin Supplement 2Health News:HJF publishes handbook on managing pain of battlefield trauma 2Health News:Hill-Rom to Present at the Bank of America 2009 Health Care Conference 2Health News:BMP Sunstone Appoints Les R. Baledge to Board of Directors 2Health News:Testosterone Undecanoate Achieves and Maintains Normal Testosterone Levels in Hypogonadal Men With Five Injections Per Year, New Data Show 2Health News:Testosterone Undecanoate Achieves and Maintains Normal Testosterone Levels in Hypogonadal Men With Five Injections Per Year, New Data Show 3Health News:Testosterone Undecanoate Achieves and Maintains Normal Testosterone Levels in Hypogonadal Men With Five Injections Per Year, New Data Show 4Health News:Testosterone Undecanoate Achieves and Maintains Normal Testosterone Levels in Hypogonadal Men With Five Injections Per Year, New Data Show 5
(Date:5/16/2013)...  Amgen (NASDAQ: AMGN ) will participate in ... 2013, at the Sheraton New York Times Square in ... Eastern Daylight Time. Joseph P. Miletich , ... Amgen, will present at the conference. Live audio of the ... website, www.amgen.com , under Investors. A replay of the ...
(Date:5/16/2013)... -- OrthoView PSL will allow individual surgeons ... widely-used OrthoView digital templating software via the Cloud and ... started. OrthoView, the leading independent provider of ... dedicated to enabling orthopaedic surgeons in hospitals and private ... film is unavailable. Over 5,000 orthopaedic surgeons in the ...
(Date:5/16/2013)... Developers of a pill bottle that wirelessly transmits ... grand prize winners in the Healthcare Innovation World Cup ... and organized by HITLAB . Winning team ... Langhauser and Mike Morena ... States will receive $50,000 in prize money. They ...
Breaking Medicine Technology:OrthoView Announces the U.S. Launch of a New, Subscription-based, Digital Planning and Templating Solution for Individual Orthopaedic Surgeons 2Wireless Pill Bottle Wins Healthcare Innovation World Cup 2Wireless Pill Bottle Wins Healthcare Innovation World Cup 3Wireless Pill Bottle Wins Healthcare Innovation World Cup 4Wireless Pill Bottle Wins Healthcare Innovation World Cup 5
... CLARA, Calif., March 7, 2011 Samplify Systems, Inc., ... medical, industrial, wireless, and scientific markets, has completed its ... enables the company to fund its rapid growth in ... new markets.  Participating in the round are Integrated Device ...
... plc (Nasdaq: WCRX ) today announced that its ... scheduled to speak at the Goldman Sachs Leveraged Finance Healthcare ... The presentation will be simultaneously webcast at ... available shortly thereafter at http://ir.wcrx.com/events.cfm . ...
Cached Medicine Technology:Samplify Systems Completes Series B Funding 2Samplify Systems Completes Series B Funding 3
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
Inquire...
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
Plastic Citrate Tube, .109M / 3.2%...
Medicine Products: