Navigation Links
LSUHSC research shows emotional stress can change brain function
Date:1/12/2011

New Orleans, LA Research conducted by Iaroslav Savtchouk, a graduate student, and S. June Liu, PhD, Associate Professor of Cell Biology and Anatomy at LSU Health Sciences Center New Orleans, has shown that a single exposure to acute stress affected information processing in the cerebellum the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation. The work is published in the January 12, 2011 issue of The Journal of Neuroscience.

The researchers found that a five-minute exposure to the odor of a predator produced the insertion of receptors containing GluR2 at the connections (synapses) between nerve cells in the brain. GluR2 is a subunit of a receptor in the central nervous system that regulates the transfer of electrical impulses between nerve cells, or neurons. The presence of GluR2 changed electrical currents in the cerebellum in a way that increased activity and altered the output of the cerebellar circuit in the brains of mice.

Our ability to learn from experience and to adapt to our environment depends upon synaptic plasticity the ability of a neuron or synapse to change its internal parameters in response to its history. A change in the GluR2 receptor subunit has been observed both during normal learning and memory as well as during many pathological processes, including drug addiction, stress, epilepsy, and ischemic stroke. However, the effect of this change on neuronal function is not fully understood.

"Our results lead to the testable prediction that emotional stress could affect motor coordination and other cerebellum-dependent cognitive functions," notes Dr. Liu. "These results are also applicable to communication in other brain regions and circuits. A long term goal is to alleviate the burden of neurological disorders such as motor dysfunctions, drug addiction, PTSD, and stroke." Next steps include further research to improve our understanding of the role GluR2 insertion plays in normal learning and functioning of the brain, why some neurons contain GluR2-lacking receptors, but not others, and how that affects their role in brain function.


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related medicine news :

1. APA gives LSUHSC psychiatry gold award for program in St. Bernard schools after Katrina
2. LA Tumor Registry at LSUHSC awarded $12 million SEER contract by NCI
3. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
4. UNC researchers investigate estrogen to prevent depression and cardiovascular disease
5. Pier Paolo Pandolfi, M.D., Ph.D., to receive Pezcoller-AACR International Award for Cancer Research
6. Feast or famine: Researchers identify leptin receptors sidekick as a target for appetite regulation
7. International research team reports major findings in prevention and treatment of blood clots
8. UNC researchers inch closer to unlocking potential of synthetic blood
9. Men with macho faces attractive to fertile women, researchers find
10. Researchers pinpoint origin of deadly brain tumor
11. European Research Council awards advanced researcher grant to KIT botanist Holger Puchta
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... Calibration, qualification, and the ... results and maintaining GMP and USP compliance. In a new webinar from METTLER ... requirements " these requirements are explained. The challenge is to determine how ...
(Date:3/28/2017)... San Francisco, CA (PRWEB) , ... March 28, 2017 , ... ... million people suffering from acne, access to quality care can be limited while the ... skincare company that offers customized prescription acne care for every customer online, today released ...
(Date:3/28/2017)... ... 28, 2017 , ... Columbus OH. Dr. Justin Harper, Founder of Juvly Aesthetics ... in the country to sit on the 2017 National Advisory Board for Allergan’s Facial ... Dr. Harper helped propel the clinic from a small start-up to number 78 in ...
(Date:3/28/2017)... ... 2017 , ... Public relations pros work hard to earn placements and ... While many results are clear, much of PR is hard to quantify. Goal-setting and ... to measurement, firms should always take an all-inclusive approach that takes both traditional and ...
(Date:3/28/2017)... ... ... Oily skin is a common and unwelcomed occurrence in people of all ages, genders and ... to the discussion of dealing with excess skin oil. “Oily skin is a challenge to ... can help remove the oily shine while keeping the skin fresh and clean,” says Dr. ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... Calif. , March 27, 2017  Cryoport, Inc. ... that it intends to offer shares of common stock ... registration statement on file with the Securities and Exchange ... and other conditions, and there can be no assurance ... completed, or as to the actual size or terms ...
(Date:3/27/2017)... March 27, 2017  A new survey ... that Medicare,s Competitive Bidding Program (CBP) significantly reduced beneficiary ... The lack of choice forces beneficiaries to switch to ... health consequences. AADE,s survey is the ... and others pointing out the inherent problems with the ...
(Date:3/27/2017)... 2017 /PRNewswire/ - INVICTUS MD STRATEGIES CORP. ("Invictus MD" ... MD is pleased to announce it has received conditional ... the TSX Venture Exchange.  Receiving the ... of significant achievements for Invictus-MD. Some of which include: ... AB Laboratories Inc. ("AB Labs"), a Licensed Producer under ...
Breaking Medicine Technology: