Navigation Links
LSUHSC awarded NIH grant to develop pneumonia vaccine
Date:10/7/2011

New Orleans, LA Dr. Judd Shellito, Chief of the Section of Pulmonary and Critical Care Medicine at LSU Health Sciences Center New Orleans, has been awarded approximately $9 million in grant funding to develop a vaccine against Pneumocystis, an important cause of pneumonia in people with HIV infection. This potentially fatal illness is the most common serious opportunistic infection in people with HIV. The 5-year grant was awarded by the National Heart Lung and Blood Institute of the National Institutes of Health.

According to the Centers for Disease Control and Prevention, Pneumocystis pneumonia (PCP), which is caused by Pneumocystis jirovecii (formerly P. carinii), is frequently the first serious illness encountered by HIV-infected persons. During the early years of the AIDS epidemic, PCP was the AIDS-defining illness for as many as two thirds of patients in the United States. Patients in the developing world without access to PCP prophylaxis or antiretroviral drugs remain at high risk, and PCP continues to develop in certain groups in industrialized countries. There is also a potential for drug resistance to develop.

While officially classified as a fungal pneumonia, Pneumocystis pneumonia does not respond to antifungal treatment. The fungus that causes it is common in the environment and does not cause illness in healthy people. Besides those with HIV, it can also cause lung infection in people whose immune function is suppressed due to cancer, chronic use of corticosteroids or other medications that weaken the immune system, or organ or bone marrow transplants.

Dr. Shellito, who is also the Lowenstein Professor and Vice Chair for Research in the Department of Medicine at LSU Health Sciences Center New Orleans' School of Medicine, has served as principal investigator on this Program Project grant which has been funded by the National Institutes of Health for 11 years. At the conclusion of the project, it will have brought nearly $17 million in federal funding to LSU Health Sciences Center New Orleans. Dr. Shellito is collaborating with Dr. Jay Kolls, who holds faculty appointments at both LSU Health Sciences Center New Orleans and the University of Pittsburgh.

"Lung infections remain an important problem for individuals infected with the HIV virus," notes Dr. Shellito. "Of these infections, one of the most severe is pneumonia caused by the fungal pathogen, Pneumocystis. This project seeks to develop a safe and effective vaccine not just to treat Pneumocystis pneumonia but to prevent it altogether. We believe that such a vaccine will lower the cost of treatment of HIV and improve the quality of life for individuals living with HIV."


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related medicine news :

1. Grant to LSUHSC Tumor Registry creates pediatric cancer research tool
2. Protein discovered at LSUHSC may suppress breast cancer growth
3. LSUHSC research finds protein that protects cancer cells from chemo and radiation therapy
4. LSUHSC research shows emotional stress can change brain function
5. APA gives LSUHSC psychiatry gold award for program in St. Bernard schools after Katrina
6. LA Tumor Registry at LSUHSC awarded $12 million SEER contract by NCI
7. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
8. Cothenius Medal awarded to Arizona State University social insect scientist for lifes work
9. Penn veterinarian Ralph Brinster awarded National Medal of Science
10. Lung cancer research team awarded $1.43 million to study cancer in Eastern Kentucky
11. UT awarded NIH grants to study prevention and treatment of neurodegenerative and vascular diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2017)... ... February 27, 2017 , ... It’s no ... which often leads to a host of health issues, including urinary incontinence. However, ... Society discovered that good overall muscle strength in older women, particularly in ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... ... for Shamanic Healing and Spiritual Awakening, is happy to announce her “Spring ... mind and body, these individual customized retreats offer the winter-weary soul an excellent ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... Elisa Guajardo Carothers is not your typical ... to studying to become a nun. Now, she writes about God, when she isn’t swimming ... Know BC and AD, Here is BS! (Before Satan),” she offers a comedic look at ...
(Date:2/27/2017)... ... February 26, 2017 , ... Miro is the ultimate smart media center that ... songs, movies, TV shows and much more apps for user exploration. Its innovative acoustic ... view of 1280 x 720 provides crisp images with remarkable clarity and color. The ...
(Date:2/27/2017)... ... 2017 , ... Sunshine Coast Health Centre (SCHC), one of ... https://www.sunshinecoasthealthcentre.ca/ , is proud to announce the addition of a registered massage ... commitment to innovation in drug rehab and alcohol treatment strategies beyond a "punishment" ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017 Physician General Dr. ... and Alcohol Programs Jennifer Smith commended South ... training for and using naloxone, a life-saving overdose reversal ... , a recovery specialist and overdose survivor who was ... providers. "A significant part of fighting the ...
(Date:2/24/2017)... , Feb. 23, 2017 The U.S. ... the PhenoTest BC Kit, performed on the Pheno ... organisms that cause bloodstream infections and provide information ... respond to (antibiotic sensitivity). The test also reduces ... this important information, which can guide antibiotic treatment ...
(Date:2/24/2017)... , Feb. 23, 2017  Directors from Pharma To Market Pty ... have joined forces, resulting in the founding of Pharma To Market ... Pharma To Market are pleased to announce their expansion into ... Singapore . The company are delighted to appoint ... of the Singapore based entity. Joelle brings ...
Breaking Medicine Technology: