Navigation Links
LSUHSC awarded NIH grant to develop pneumonia vaccine
Date:10/7/2011

New Orleans, LA Dr. Judd Shellito, Chief of the Section of Pulmonary and Critical Care Medicine at LSU Health Sciences Center New Orleans, has been awarded approximately $9 million in grant funding to develop a vaccine against Pneumocystis, an important cause of pneumonia in people with HIV infection. This potentially fatal illness is the most common serious opportunistic infection in people with HIV. The 5-year grant was awarded by the National Heart Lung and Blood Institute of the National Institutes of Health.

According to the Centers for Disease Control and Prevention, Pneumocystis pneumonia (PCP), which is caused by Pneumocystis jirovecii (formerly P. carinii), is frequently the first serious illness encountered by HIV-infected persons. During the early years of the AIDS epidemic, PCP was the AIDS-defining illness for as many as two thirds of patients in the United States. Patients in the developing world without access to PCP prophylaxis or antiretroviral drugs remain at high risk, and PCP continues to develop in certain groups in industrialized countries. There is also a potential for drug resistance to develop.

While officially classified as a fungal pneumonia, Pneumocystis pneumonia does not respond to antifungal treatment. The fungus that causes it is common in the environment and does not cause illness in healthy people. Besides those with HIV, it can also cause lung infection in people whose immune function is suppressed due to cancer, chronic use of corticosteroids or other medications that weaken the immune system, or organ or bone marrow transplants.

Dr. Shellito, who is also the Lowenstein Professor and Vice Chair for Research in the Department of Medicine at LSU Health Sciences Center New Orleans' School of Medicine, has served as principal investigator on this Program Project grant which has been funded by the National Institutes of Health for 11 years. At the conclusion of the project, it will have brought nearly $17 million in federal funding to LSU Health Sciences Center New Orleans. Dr. Shellito is collaborating with Dr. Jay Kolls, who holds faculty appointments at both LSU Health Sciences Center New Orleans and the University of Pittsburgh.

"Lung infections remain an important problem for individuals infected with the HIV virus," notes Dr. Shellito. "Of these infections, one of the most severe is pneumonia caused by the fungal pathogen, Pneumocystis. This project seeks to develop a safe and effective vaccine not just to treat Pneumocystis pneumonia but to prevent it altogether. We believe that such a vaccine will lower the cost of treatment of HIV and improve the quality of life for individuals living with HIV."


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related medicine news :

1. Grant to LSUHSC Tumor Registry creates pediatric cancer research tool
2. Protein discovered at LSUHSC may suppress breast cancer growth
3. LSUHSC research finds protein that protects cancer cells from chemo and radiation therapy
4. LSUHSC research shows emotional stress can change brain function
5. APA gives LSUHSC psychiatry gold award for program in St. Bernard schools after Katrina
6. LA Tumor Registry at LSUHSC awarded $12 million SEER contract by NCI
7. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
8. Cothenius Medal awarded to Arizona State University social insect scientist for lifes work
9. Penn veterinarian Ralph Brinster awarded National Medal of Science
10. Lung cancer research team awarded $1.43 million to study cancer in Eastern Kentucky
11. UT awarded NIH grants to study prevention and treatment of neurodegenerative and vascular diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the ... in the world, and the most handsome men, look naturally attractive. Plastic surgery ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Venture Construction ... Classic Tournament held on June 20th at the Woodmont Country Club at 1201 ... Wings, an organization dedicated to helping service members that have been wounded in battle ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
Breaking Medicine Technology: