Navigation Links
LSUHSC awarded NIH grant to develop pneumonia vaccine
Date:10/7/2011

New Orleans, LA Dr. Judd Shellito, Chief of the Section of Pulmonary and Critical Care Medicine at LSU Health Sciences Center New Orleans, has been awarded approximately $9 million in grant funding to develop a vaccine against Pneumocystis, an important cause of pneumonia in people with HIV infection. This potentially fatal illness is the most common serious opportunistic infection in people with HIV. The 5-year grant was awarded by the National Heart Lung and Blood Institute of the National Institutes of Health.

According to the Centers for Disease Control and Prevention, Pneumocystis pneumonia (PCP), which is caused by Pneumocystis jirovecii (formerly P. carinii), is frequently the first serious illness encountered by HIV-infected persons. During the early years of the AIDS epidemic, PCP was the AIDS-defining illness for as many as two thirds of patients in the United States. Patients in the developing world without access to PCP prophylaxis or antiretroviral drugs remain at high risk, and PCP continues to develop in certain groups in industrialized countries. There is also a potential for drug resistance to develop.

While officially classified as a fungal pneumonia, Pneumocystis pneumonia does not respond to antifungal treatment. The fungus that causes it is common in the environment and does not cause illness in healthy people. Besides those with HIV, it can also cause lung infection in people whose immune function is suppressed due to cancer, chronic use of corticosteroids or other medications that weaken the immune system, or organ or bone marrow transplants.

Dr. Shellito, who is also the Lowenstein Professor and Vice Chair for Research in the Department of Medicine at LSU Health Sciences Center New Orleans' School of Medicine, has served as principal investigator on this Program Project grant which has been funded by the National Institutes of Health for 11 years. At the conclusion of the project, it will have brought nearly $17 million in federal funding to LSU Health Sciences Center New Orleans. Dr. Shellito is collaborating with Dr. Jay Kolls, who holds faculty appointments at both LSU Health Sciences Center New Orleans and the University of Pittsburgh.

"Lung infections remain an important problem for individuals infected with the HIV virus," notes Dr. Shellito. "Of these infections, one of the most severe is pneumonia caused by the fungal pathogen, Pneumocystis. This project seeks to develop a safe and effective vaccine not just to treat Pneumocystis pneumonia but to prevent it altogether. We believe that such a vaccine will lower the cost of treatment of HIV and improve the quality of life for individuals living with HIV."


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related medicine news :

1. Grant to LSUHSC Tumor Registry creates pediatric cancer research tool
2. Protein discovered at LSUHSC may suppress breast cancer growth
3. LSUHSC research finds protein that protects cancer cells from chemo and radiation therapy
4. LSUHSC research shows emotional stress can change brain function
5. APA gives LSUHSC psychiatry gold award for program in St. Bernard schools after Katrina
6. LA Tumor Registry at LSUHSC awarded $12 million SEER contract by NCI
7. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
8. Cothenius Medal awarded to Arizona State University social insect scientist for lifes work
9. Penn veterinarian Ralph Brinster awarded National Medal of Science
10. Lung cancer research team awarded $1.43 million to study cancer in Eastern Kentucky
11. UT awarded NIH grants to study prevention and treatment of neurodegenerative and vascular diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... July 19, 2017 , ... ... a larger audience and increased funds raised to support fine arts programs in ... “Disney Aladdin Kids” in Freed-Hardeman University’s Loyd Auditorium. , More than 850 ...
(Date:7/20/2017)... ... July 19, 2017 , ... Adolfson & ... project manager, Josh Christensen. As a leader in healthcare construction, AP has successfully ... healthcare resume in the Midwest with Josh now on board. , Josh ...
(Date:7/18/2017)... (PRWEB) , ... July 18, 2017 , ... CannaKids, a ... extracted cannabis oils, announced today that at the WORLDZ Summit, taking place in ... speaking on the therapeutic benefits of medical cannabis for both pediatric and adult patients, ...
(Date:7/18/2017)... ... , ... An inventor from Anacortes, Wash., knows the difficulties and indignity of ... flashes, and I suffer from anxiety and vertigo on top of that," she said, ... about." INSTA-FAN meets that need. , This device enables a woman in menopause to ...
(Date:7/17/2017)... ... July 17, 2017 , ... ... and Its Treatments during Pregnancy , studies take a closer look at maternal ... a developing baby with one study showing newer medications may be safer choices. ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... ROCKVILLE, Md. , July 13, 2017  New York ... watchers of pharmaceutical markets should be aware of.  From new ... These trends are detailed in a recently completed study, ... following: 1.  Age-Driven ... years, we have been aware of the impact the growing ...
(Date:7/12/2017)... 2017  Eli Lilly and Company (NYSE: LLY ... to resolve pending patent litigation in the U.S. District Court ... regarding the Cialis ® (tadalafil) unit dose patent. This ... As part of the agreement, Cialis exclusivity is now expected ... "The unit dose patent for Cialis is valid and ...
(Date:7/11/2017)... , July 11, 2017  Bayer has awarded grants ... countries as part of its prestigious Bayer Hemophilia Awards Program ... of Philadelphia and Uniformed Services University ... are among the winners. Grant recipients were announced last night ... Hemostasis (ISTH) 2017 Congress, Berlin, Germany . ...
Breaking Medicine Technology: