Navigation Links
LSUHSC awarded NIH grant to develop pneumonia vaccine
Date:10/7/2011

New Orleans, LA Dr. Judd Shellito, Chief of the Section of Pulmonary and Critical Care Medicine at LSU Health Sciences Center New Orleans, has been awarded approximately $9 million in grant funding to develop a vaccine against Pneumocystis, an important cause of pneumonia in people with HIV infection. This potentially fatal illness is the most common serious opportunistic infection in people with HIV. The 5-year grant was awarded by the National Heart Lung and Blood Institute of the National Institutes of Health.

According to the Centers for Disease Control and Prevention, Pneumocystis pneumonia (PCP), which is caused by Pneumocystis jirovecii (formerly P. carinii), is frequently the first serious illness encountered by HIV-infected persons. During the early years of the AIDS epidemic, PCP was the AIDS-defining illness for as many as two thirds of patients in the United States. Patients in the developing world without access to PCP prophylaxis or antiretroviral drugs remain at high risk, and PCP continues to develop in certain groups in industrialized countries. There is also a potential for drug resistance to develop.

While officially classified as a fungal pneumonia, Pneumocystis pneumonia does not respond to antifungal treatment. The fungus that causes it is common in the environment and does not cause illness in healthy people. Besides those with HIV, it can also cause lung infection in people whose immune function is suppressed due to cancer, chronic use of corticosteroids or other medications that weaken the immune system, or organ or bone marrow transplants.

Dr. Shellito, who is also the Lowenstein Professor and Vice Chair for Research in the Department of Medicine at LSU Health Sciences Center New Orleans' School of Medicine, has served as principal investigator on this Program Project grant which has been funded by the National Institutes of Health for 11 years. At the conclusion of the project, it will have brought nearly $17 million in federal funding to LSU Health Sciences Center New Orleans. Dr. Shellito is collaborating with Dr. Jay Kolls, who holds faculty appointments at both LSU Health Sciences Center New Orleans and the University of Pittsburgh.

"Lung infections remain an important problem for individuals infected with the HIV virus," notes Dr. Shellito. "Of these infections, one of the most severe is pneumonia caused by the fungal pathogen, Pneumocystis. This project seeks to develop a safe and effective vaccine not just to treat Pneumocystis pneumonia but to prevent it altogether. We believe that such a vaccine will lower the cost of treatment of HIV and improve the quality of life for individuals living with HIV."


'/>"/>

Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center
Source:Eurekalert

Related medicine news :

1. Grant to LSUHSC Tumor Registry creates pediatric cancer research tool
2. Protein discovered at LSUHSC may suppress breast cancer growth
3. LSUHSC research finds protein that protects cancer cells from chemo and radiation therapy
4. LSUHSC research shows emotional stress can change brain function
5. APA gives LSUHSC psychiatry gold award for program in St. Bernard schools after Katrina
6. LA Tumor Registry at LSUHSC awarded $12 million SEER contract by NCI
7. LSUHSC study finds early predictors of metabolic syndrome in healthy 7-9 year-olds
8. Cothenius Medal awarded to Arizona State University social insect scientist for lifes work
9. Penn veterinarian Ralph Brinster awarded National Medal of Science
10. Lung cancer research team awarded $1.43 million to study cancer in Eastern Kentucky
11. UT awarded NIH grants to study prevention and treatment of neurodegenerative and vascular diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... (PRWEB) , ... February 13, 2016 , ... When an Au Pair comes ... always sure what they are in for and they are often worried things won’t go ... they were hoping for. This year’s Au Pair of the Year winner’s all commented how ...
(Date:2/12/2016)... ... , ... Mystic Buddha Publishing House presents Valentine’s Day tips on different forms ... - Dr. Frederick Lenz. , According to Publisher Roger Cantu, “Blue Skies ... teaching and helping others. Valentine’s Day celebrates love in all its forms, and ...
(Date:2/12/2016)... ... ... , Back to the Future , Feb. 25, 2016 — 11:00 a.m. – 12:30 p.m. ... learn from history are doomed to repeat it.” , An analysis of CDRH’s enforcement actions ... takes time. , Take a close look at the warning letters the agency sent ...
(Date:2/12/2016)... ... February 12, 2016 , ... Coco Libre, the maker of coconut ... Events LA GRAMMY’s Style Lounge Event. Coco Libre will offer musicians and celebrities the ... the big event. The invitation-only gifting suite, held this year at the W Hollywood ...
(Date:2/12/2016)... ... 12, 2016 , ... Every winter, someone is killed, injured or loses a ... Burn Center, part of the Allegheny Health Network, has partnered with Etna Volunteer ... Heaters Need Space” campaign. , “Space Heaters Need Space” aims to bring ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... SEOUL, South Korea , Feb. 12, ... Inc. today announced they will form a partnership ... precision medicine in cancer. The goal of the ... technology with Macrogen,s high-throughput Next Generation Sequencing capabilities ... Clinical Laboratory Improvement Amendments (CLIA) of 1988 by ...
(Date:2/12/2016)... North Carolina , 12 februari 2016 ... Inc. (AAI/CML), een toonaangevende leverancier van productie ... en biotechnologische industrieën, kondigt vandaag een uitbreiding ... mogelijkheden op haar locatie in ... vraag heeft geleid tot meerdere recente investeringen. ...
(Date:2/11/2016)... - Cardiac Marker Diagnostic ... and Cancer Therapy. - European Point of Care ... - Key Diagnostic Testing Markets. - Molecular ... Genetic Testing. - Molecular Diagnostics in Infectious Disease ... Diagnostic Products World Markets. - Point of Care ...
Breaking Medicine Technology: