Navigation Links
LSTM and MiP Consortium awarded further $4.5 million
Date:3/5/2009

The Malaria in Pregnancy Consortium, led by the Liverpool School of Tropical Medicine, has been awarded 3.6 million by the European and Developing Countries Clinical Trials Partnership (EDCTP) to undertake research aimed at optimising the use of an antimalarial drug given to prevent malaria in pregnancy in Africa.

Malaria in pregnancy is a major cause of severe maternal anaemia and preventable low birth weight in infants, which greatly increases the risk of infant death, hence pregnant women showing no malaria symptoms are encouraged to take antimalarial drugs to prevent infection. Intermittent preventive treatment (IPTp) has proven highly effective in reducing the adverse effects of malaria infection in pregnant women and improving birth weight (and hence survival rates) in infants. This project is seeking to optimise the regimen of a particular drug, sulphadoxine-pyrimethamine or SP, which is used widely as IPTp and is looking at alternative approaches to IPTp.

Consortium leader and project co-ordinator Professor Feiko ter Kuile from the Liverpool School of Tropical Medicine explained the significance and future relevance of the activities: "SP is one of the main antimalarials used for the control of malaria in pregnancy, but despite ten years of widespread use, uncertainties about the optimal dose remain. This project will allow us to explore whether pregnant women need a different dose than non-pregnant women because of changes in the way the drug is assimilated during pregnancy.

"It will also allow us to determine whether alternative drug based approaches to control malaria in pregnancy are feasible when the mother is successfully using an insecticide treated bednet to protect her from mosquito bites. The results of this research will be used to inform WHO policy recommendations on the use of SP."

The project involves four European partners in the UK, Austria and Denmark and five African institutions in Malawi, Ghana, The Gambia, Mali and Burkina Faso. It will include a significant element of capacity building in the African host nations, including infrastructural upgrading of five research sites in Africa and a series of short term training courses in clinical trial methodology, research ethics, statistics and research management. Longer term training will involve MSc studentships and PhD scholarships.

The project is part of the global Malaria in Pregnancy (MiP) Consortium's 5-year research agenda and is closely linked with two companion MiP projects also funded by EDCTP, led by MiP Consortium members the Centre for International Health Research, Barcelona and the Prince Leopold Institute of Tropical Medicine, Antwerp.


'/>"/>

Contact: Alan Hughes
a.p.hughes@liv.ac.uk
Liverpool School of Tropical Medicine
Source:Eurekalert

Related medicine news :

1. Autism Consortium releases data on genes involved in autism to researchers worldwide
2. UMass Consortium awarded $300,000 from Juvenile Diabetes Research Foundation and Iacocca Foundation
3. Elan Pharmaceuticals Joins GeneGos MetaTox Consortium
4. Consortium Health Plans Cuts Down on Power Usage and Cooling in Its Data Center Using ONStors Green Clustered NAS Solution
5. Gordon & Rees LLP Joins ArlenGroup-CIGNA Health Care Purchasing Consortium
6. International consortium announces the 1000 Genomes Project
7. Cancer Vaccine Consortium and Cancer Vaccine Collaborative unite under the Cancer Research Institute
8. Geriatric Oncology Consortium (GOC) Announces Tampa Bay Road Rally to Raise Awareness for the Treatment of Seniors With Cancer
9. Siemens Consortium to Construct Particle Therapy Center at the University Clinic of Schleswig-Holstein
10. SAE-Funded CAESAR(TM) Project Earns Federal Laboratory Consortium Award
11. Neuroscience Peer Review Consortium announces increased journal participation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history of ... Brink” is the creation of published author, William Nowers. Captain Nowers and his ... veteran, he spent thirty years in the Navy. Following his career as a ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: ... develop to enable prevention of a major side effect of chemotherapy in children. ... pediatric patients. For cisplatin, hearing loss is FDA listed on-label as a dose ...
(Date:10/12/2017)... Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... is holding a treadmill relay – Miles by Moonlight to raise money for the ... donating $300 or more. , Teams will work together to keep their treadmills ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief Medical Officer Dr. ... colleagues, skilled nursing facility medical directors and other clinicians at various events in ... , "At many of these conferences we get to educate other physicians, facility ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/19/2017)... venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound ... ... Jim Bertolina, PhD ... Tom Tefft ... device executive Josh Stopek , PhD, who has led R&D and business development teams ...
(Date:9/12/2017)... 12, 2017   EcoVadis , the leading platform for environmental, social ... annual edition of its Global CSR Risk and Performance Index. The report ... based on Scorecard Ratings that analyzed nearly 800,000 data points across the ... ... ...
Breaking Medicine Technology: