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LA BioMed receives Grand Challenges Explorations grant
Date:5/15/2012

CPAP) via the nose throughout the respiratory cycle during spontaneous breathing has revolutionized the treatment of respiratory failure in premature infants.

Nasal CPAP assists in opening and keeping open the lungs from birth onwards and is applicable in both high and low technical settings. If this noninvasive approach fails, the next step is to insert a breathing tube, start mechanical ventilation, and instill a clinical lung surfactant into the airways. This approach is not only invasive, but may damage the lungs and requires advanced skills and equipment. Delivery of an advanced synthetic lung surfactant as an aerosol will open up the possibility to use this rescue treatment in a non-invasive way. The combination of nasal CPAP and aerosolized synthetic lung surfactant will first be tested in a laboratory setting. If successful , this new approach will be further developed for clinical use.


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Contact: Diana Soltesz
diana@dsmmedia.com
818-592-6747
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
Source:Eurekalert

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