Navigation Links
L’Oréal Fellowship winner seeks to improve blood cancer treatments
Date:8/21/2012

A desire to improve the survival of people with blood cancers and reduce the side-effects of their anti-cancer treatments has seen Walter and Eliza Hall Institute researcher Dr Kylie Mason today win one of three 2012 L'Oral Australia For Women in Science Fellowships.

The work of Dr Mason, a senior postdoctoral fellow in the institute's Cancer and Haematology division and a clinical haematologist at The Royal Melbourne Hospital, has set the benchmark for evaluating a new class of anti-cancer agents called BH3-mimetics.

In 2006 Dr Mason was part of the Walter and Eliza Hall Institute team which found that the BH3-mimetic ABT-737 ceased being effective in the presence of a protein called Mcl-1. "Mcl-1 is switched on in many tumours so this finding had significant repercussions for the development of BH3-mimetics, which hold promise for treating chemotherapy-resistant tumours," Dr Mason said.

Her subsequent studies showed that ABT-737 remained effective in killing chemotherapy-resistant tumours when combined with standard chemotherapy. They also revealed the first chapters of a much bigger story: that of platelets and their lifespan.

One of the side-effects of treatment with ABT-737 is acute thrombocytopenia (low platelet count). Dr Mason's studies have shown that while ABT-737 is directly toxic to circulating platelets, it does not affect their production in the bone marrow. "This finding provided the first indication that platelets could undergo programmed cell death," Dr Mason said.

In collaboration with Dr Ben Kile and others at the Walter and Eliza Hall Institute, Dr Mason showed that platelets the blood cells responsible for clotting are programmed to die, containing a molecular 'clock' that dictates their lifespan.

"This work has profound implications for the diagnosis and treatment of disorders that affect platelets," she said. "It also has critical implications for improved blood bank storage of plate
'/>"/>

Contact: Penny Fannin
fannin@wehi.edu.au
61-417-125-700
Walter and Eliza Hall Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Loyola Stritch, Niehoff students receive prestigious Schweitzer Fellowships
2. Fewer prostate cancer surgery complications found in teaching hospitals with fellowship programs
3. Damon Runyon Cancer Research Foundation grants fellowship awards to 21 top young scientists
4. MCG student receives national medical honor society research fellowship
5. Which ads are winners? Your brain knows better than you do
6. Nordic Walking a Winner for Heart Failure Patients, Study Says
7. USHEALTH Advisors L.L.C. Honored as Bronze Stevie® Award Winner in 2012 American Business Awards
8. Excellence Initiative winner TU München invests in the future: Young researchers
9. FDA Seeks to Limit Antibiotics in Animal Feed
10. Trial seeks to sniff out cancer
11. Electronic data methods research seeks to build a learning health care system
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Coast Dental and Orthodontics is ... practice, located at 1010 Shaw Avenue in Clovis, CA. ... services , and specialty dental care including orthodontics, endodontics, ... and convenient dental care, our Clovis dentists also strive ... Coast Dental at 559-777-6113 to schedule an appointment. , ...
(Date:9/30/2014)... how resveratrol, an antioxidant derived from grapes and found ... that causes acne. , The team also found that ... may enhance the drug,s ability to kill the bacteria ... the current online edition of the journal Dermatology ... resveratrol and benzoyl peroxide attack the acne bacteria, called ...
(Date:9/30/2014)... Michigan are pleased to announce an agreement to publish ... Endocrinology , which is now open for submissions and ... , The journal is led by Editor-in-Chief, Meng ... Metabolism, Endocrinology, and Diabetes, at the University of Michigan, ... international Editorial Board. , Clinical Diabetes and ...
(Date:9/30/2014)... valuable procedure by which to screen for the ... healthy Americans who do undergo this sometimes uncomfortable ... actually should. Gina Kruse of Massachusetts General ... endoscopists stick to the national guidelines more closely. ... General Internal Medicine , published by Springer. ...
(Date:9/30/2014)... September 30, 2014 MyServer2Go.com ... as the Best VPS Hosting this year for its ... as affordable price. , MyServer2Go.com is a professional ... VPS hosting services. And this announcement will help webmasters ... According to MyServer2Go.com, Arvixe ( http://www.arvixe.com ) is one ...
Breaking Medicine News(10 mins):Health News:Coast Dental Clovis Celebrates Grand Opening 2Health News:Coast Dental Clovis Celebrates Grand Opening 3Health News:Antioxidant found in grapes uncorks new targets for acne treatment 2Health News:Antioxidant found in grapes uncorks new targets for acne treatment 3Health News:BioMed Central to publish open access journal in collaboration with the University of Michigan 2Health News:Americans undergo colonoscopies too often, study finds 2Health News:Arvixe Is Named Best VPS Hosting by MyServer2Go.com 2
... of a woman diagnosed with breast cancer is 63, so ... older patient population. But older women with breast cancer are ... the effects of chemotherapy used in addition to other therapies ... May 14 issue of The New England Journal of ...
... (NYSE Alternext US: ADL), a US-based pharmaceutical company with ... into two distinct five-year marketing and distribution agreements with ... provider, whereby GenWay Biotech will ... the US and Canada. The partnership significantly advances ...
... award winning mobile health care solution - OnCare by Gearworks - will ... Association of America (VNAA) 27th Annual Meeting from May 14-16, 2009 in ... ... -- Gearworks , a leading provider of location-based mobile business applications, ...
... WASHINGTON, May 13 "On behalf of the 157,000 ... I would like to thank Congressman Mike Simpson for ... -- a resolution yesterday congratulating the ADA on its ... vigilant on behalf of its members, the ADA nonetheless ...
... XLHealth, owner and operator of Care Improvement Plus, one ... Needs Plans, views the Social Security and Medicare Trustees ... address the needs of the chronically ill. Along with ... timeline toward Medicare insolvency includes spending associated with chronically ...
... American Nurses Pledges Support for Legislation SILVER SPRING, Md., ... vowed support for legislation that will protect nurses from ... Health Care Worker Protection Act of 2009 (H.R. 2381), ... to develop and implement a standard to eliminate manual ...
Cached Medicine News:Health News:Study shows chemotherapy improves survival among older breast cancer patients 2Health News:AMDL, Inc. Enters Into Distribution Agreements With GenWay Biotech, Inc. to Advance Commercialization of the DR-70 (FDP) Cancer Test in the US and Canada 2Health News:AMDL, Inc. Enters Into Distribution Agreements With GenWay Biotech, Inc. to Advance Commercialization of the DR-70 (FDP) Cancer Test in the US and Canada 3Health News:AMDL, Inc. Enters Into Distribution Agreements With GenWay Biotech, Inc. to Advance Commercialization of the DR-70 (FDP) Cancer Test in the US and Canada 4Health News:Gearworks to Exhibit OnCare at VNAA 27th Annual Meeting 2Health News:Gearworks to Exhibit OnCare at VNAA 27th Annual Meeting 3Health News:Statement by American Dental Association President John S. Findley on Passage of H.Res. 204, a Congressional Resolution Congratulating the Association for its 150 Years of Service 2Health News:XLHealth Statement on Social Security and Medicare Trustees Report 2Health News:Common-Sense Patient Handling Bill Protects Patients and Nurses 2
(Date:9/30/2014)... , Sept. 30, 2014  eHealth, electronic access ... and access of this information, has become a ... however, that has not translated into user-friendly, effective ... Photo - http://photos.prnewswire.com/prnh/20140929/149123 ... few years developing MWD® Health Manager iEHR, a ...
(Date:9/30/2014)... Sept. 30, 2014  RFID Journal announced today that registration ... www.rfidjournalevents.com/healthcare ), the premier industry event focused on the ... care sector. The conference and exhibition will be held ... Place in Chicago, Ill. ... executives explaining how they use RFID to improve asset-utilization ...
(Date:9/30/2014)... , Sept. 30, 2014  Come fall, many ... "who" or "what" they want to be for Halloween. ... their look with decorative contact lenses bought without a ... of year that people purchase and wear contact lenses ... 2013 American Eye-Q ® consumer survey, 17 percent ...
Breaking Medicine Technology:MWD Challenges the Big eHealth Players With New Software for Your Smartphone 2Hear New Case Studies from Industry Leaders at RFID in Health Care 2014 2Hear New Case Studies from Industry Leaders at RFID in Health Care 2014 3The Spooky Truth: What You Need To Know About Contact Lens Hygiene 2The Spooky Truth: What You Need To Know About Contact Lens Hygiene 3
... Mylan Inc. (Nasdaq: MYL ) today announced ... the company,s 6.50% Mandatory Convertible Preferred Stock (the "Preferred ... As previously announced, each share converted into 58.5480 shares ... the Articles of Incorporation, reflecting strong stock performance since ...
... YORK, Nov. 15, 2010 Reportlinker.com announces that ... its catalogue: Global Ophthalmic Instrumentation ... This report analyzes the worldwide markets ... US$ Million by the following segments: Diagnostic Devices ...
Cached Medicine Technology:Reportlinker Adds Global Ophthalmic Instrumentation Industry 2Reportlinker Adds Global Ophthalmic Instrumentation Industry 3Reportlinker Adds Global Ophthalmic Instrumentation Industry 4Reportlinker Adds Global Ophthalmic Instrumentation Industry 5Reportlinker Adds Global Ophthalmic Instrumentation Industry 6Reportlinker Adds Global Ophthalmic Instrumentation Industry 7Reportlinker Adds Global Ophthalmic Instrumentation Industry 8Reportlinker Adds Global Ophthalmic Instrumentation Industry 9Reportlinker Adds Global Ophthalmic Instrumentation Industry 10Reportlinker Adds Global Ophthalmic Instrumentation Industry 11Reportlinker Adds Global Ophthalmic Instrumentation Industry 12Reportlinker Adds Global Ophthalmic Instrumentation Industry 13Reportlinker Adds Global Ophthalmic Instrumentation Industry 14Reportlinker Adds Global Ophthalmic Instrumentation Industry 15Reportlinker Adds Global Ophthalmic Instrumentation Industry 16Reportlinker Adds Global Ophthalmic Instrumentation Industry 17Reportlinker Adds Global Ophthalmic Instrumentation Industry 18Reportlinker Adds Global Ophthalmic Instrumentation Industry 19Reportlinker Adds Global Ophthalmic Instrumentation Industry 20Reportlinker Adds Global Ophthalmic Instrumentation Industry 21Reportlinker Adds Global Ophthalmic Instrumentation Industry 22Reportlinker Adds Global Ophthalmic Instrumentation Industry 23Reportlinker Adds Global Ophthalmic Instrumentation Industry 24Reportlinker Adds Global Ophthalmic Instrumentation Industry 25
Polyester ribbon impregnated with conjugated Protein G - .13 OD per sq. cm....
Colloidal Gold Sol, 40 nm - 12 - 15, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... glass (1.5x) Gonio lens will enable visualization ... 4 mirror lens is the industry preferred ... and features : , Crispest, clearest ... previously unattainable with Gonio lenses., 4 equally ...
Colloidal Gold Sol, 20 nm - 50 OD, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
Medicine Products: