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Kinovate Life Sciences, Inc. and Nitto Denko Corporation Announce Successful Development of NittoPhase™ HL High Loading Solid Support for Oligonucleotide Synthesis
Date:5/15/2009

sting to date and expect to be able to deliver this product at a price that will make a significant impact on per micromole costs for our customers. Following on from the extraordinary success of our original NittoPhase™ Solid Support product, which has fast become well established as the market leading solid support in the therapeutic oligonucleotide industry, NittoPhase™ HL will cement Kinovate's position as the market leader in this field," stated Dr. Kenji Matsumoto, President of Kinovate Life Sciences, Inc.

ABOUT SOLID SUPPORT
Manufacture of oligonucleotide drugs involves use of solid support matrix upon which chemical reactions occur in a cyclic manner. These reactions are performed on a fully automated synthesizer. At the end of synthesis, drugs are purified by various chromatographic techniques and characterized extensively to check their authenticity and purity. Thus solid support plays a crucial role in the manufacture of oligonucleotide drugs. It is increasingly believed that the yield of full-length oligonucleotide product is greatly influenced by the proper design of a polymeric support which undergoes roughly eighty chemical reactions in about eight hours for a 20-mer oligonucleotide.

ABOUT KINOVATE LIFE SCIENCES
Kinovate Life Sciences, Inc. is a subsidiary of Nitto Denko Corporation (Osaka, Japan). Whose mission is the commercialization and marketing of life science-related technologies developed by Nitto Denko Corporation and its Oceanside, CA based R&D subsidiary company Nitto Denko Technical Corporation. In April 2005, Kinovate launched NittoPhase™ Solid Support for Oligonucleotide Synthesis, which has gone on to became the market leading product in its class.

ABOUT NITTO DENKO CORPORATION
Incorporated in 1918 and having its head office in Osaka, Japan, Nitto Denko Corporation designs, manufactures and sells a wide range of products including adhesive tapes, electronic components,
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