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Kimmel Cancer Center at Jefferson breast cancer symposium features latest in research, treatment
Date:4/6/2011

PHILADELPHIAThe latest advances in both breast cancer treatment and research including innovations in diagnostic, surgical, chemotherapy and radiation approaches will be discussed Friday, April 8, 2011, at a breast cancer symposium at the Kimmel Cancer Center at Jefferson in Philadelphia.

The all-day, breast cancer symposium, part of an annual series at the Kimmel Cancer Center, will be held at the Bluemle Life Sciences Building, 233 S. 10th Street, beginning at 8:30 a.m.

"Treating breast cancer is a multidisciplinary effort, with input from a variety of specialists, such as pathologists, surgeons, radiation oncologists, and medical oncologists, who make decisions about patient treatment and care," says Richard Pestell, M.D., Ph.D., director of the Kimmel Cancer Center at Jefferson and professor and chair of cancer biology at Jefferson Medical College of Thomas Jefferson University.

"This symposium is an opportunity for those players to come together and highlight the innovative discoveries we believe will be important for the next generation of therapeutics in breast cancer patients," he adds.

A range of topics will be covered by top experts here at Jefferson and other institutions in the United States.

Michael Lisanti, M.D., professor of cancer biology at Jefferson Medical College, will discuss his recent work with new models for cancer, "The Reverse Warburg Effect" and "The Autophagic Tumor Stroma Model of Cancer." His studies have shown how mitochondrial oxidative stress plays a role in cancer development and how cancer metabolism can be used to predict clinical outcomes.

"High-risk breast cancer patientsthose whose cancer cells use high-energy metabolitescan be treated with new therapeutics that target oxidative mitochondrial metabolism," Dr. Lisanti said. "We should re-consider using antioxidants and autophagy inhibitors as anti-cancer agents."

There will also be presentations by Hallgeir
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Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

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