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Kidneys: Produce-rich diet improves long-term health, melatonin improves short-term health
Date:11/20/2010

1. Kidney Disease Patients Benefit from a Diet High in Fruits and Vegetables Healthy Foods Can Help Maintain Kidney Function

In patients with kidney disease, the Western diet produces an acidic environment in the body that has numerous negative effects and worsens with age as kidney function declines. Nimirit Goraya, MD (Texas A&M College of Medicine and Scott and White Healthcare) and her colleagues conducted a study to see if consuming a diet high in fruits and vegetables that counteract this acidity might improve the kidney health of 40 patients who have moderately reduced kidney function due to high blood pressure. 30 days of this diet reduced urine excretion of three indicators of kidney injury: albumin, transforming growth factor, and N-acetyl-β-D- glucosaminidase. "These preliminary studies support the need for larger long-term studies to determine if this simple and relatively inexpensive intervention helps reduce the risk of subsequent worsening of kidney function in patients with hypertension-associated kidney disease," said Dr. Goraya.

Study co-authors include Jan Simoni, PhD (Texas Tech University Health Sciences); Kristine Broglio (Texas A&M University); and Donald E. Wesson, MD (Texas A&M College of Medicine and Scott and White Healthcare).

Disclosures: The authors reported no financial disclosures.

The study abstract, "Adding Dietary Fruits and Vegetables Reduces Kidney Injury in Subjects with Moderately Reduced GFR," [SA-PO2343] will be presented as a poster on Saturday, November 20, 2010 from 10:00 AM - 12:00 PM MT in Exhibit Halls A & F of the Colorado Convention Center in Denver, CO.

2. Melatonin Improves Dialysis Patients' Sleep Hormone's Effects Do Not Persist, Though

Sleep disorders are common in kidney disease patients on dialysis due to a disturbance in their biological clocks. Marije Russcher, PharmD, Birgit Koch, PharmD, PhD, (Meander Medical Center, in
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Contact: Shari Leventhal
sleventhal@asn-online.org
202-416-0658
American Society of Nephrology
Source:Eurekalert

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