Navigation Links
Kidney disease increases the risk of stroke in patients
Date:3/4/2009

OAKLAND, Calif., March 4, 2009 Chronic kidney disease increases the risk of stroke in patients with atrial fibrillation (AF), the most common type of heart arrhythmia, according to a new study by Kaiser Permanente researchers in the current online issue of Circulation.

It has long been known that chronic kidney disease is a risk factor for cardiovascular disease. This study is the first to look at whether chronic kidney disease independently increases risk of stroke in patients with AF. AF occurs when rapid, disorganized electrical signals in the heart's two upper chambers (the atria) cause the heart to contract fast and irregularly, they explain.

The finding is an important addition to the evidence base because atrial fibrillation affects more than 2.2 million Americans, particularly those 75 and older, and increases the risk of stroke nearly four fold, according to the researchers. In this study, the researchers looked at whether kidney disease increased the risk of ischemic stroke -- the most common kind of stroke that occurs when an artery to the brain in blocked.

The risk of stroke varies according to several demographic and clinical characteristics and current risk assessment strategies can be limited, according to the study's lead author Alan S. Go MD, Director of the Comprehensive Clinical Research Unit at the Kaiser Permanente Division of Research. "Our study suggests that kidney function may provide an additional clue about how to best assess stroke risk and decide upon the best prevention strategy for patients with AF," Go said.

The research is part of the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study, a decade-long, multi-center study looking at the risk factors for complications related to atrial fibrillation. In the ATRIA Study cohort of 13,535 adults with AF, the researchers assessed kidney function in two ways and found that a lower level of kidney function was associated with a graded, increased risk of ischemic stroke and blood clots that travel through the circulatory system, independent of known risk factors for AF. The magnitude of the associations for both measures of kidney function was in the range seen for other known stroke factors in AF patients, such as older age, heart failure, hypertension, diabetes, and being female.

Kidney disease may increases the risk of stroke in patients with AF by causing inflammation and stiffening of arteries. Also, decreased kidney function itself may be a marker for the build up of plaque in the arteries, explains Go.

In addition to the large, diverse sample of patients with AF, this study was strengthened by long-term longitudinal information on kidney function and the ability to characterize periods off anticoagulants, validating the occurrence of ischemic stroke, and the accounting for the presence of other known risk factors for stroke during follow up.


'/>"/>

Contact: Danielle Cass
Danielle.X.Cass@kp.org
510-267-5354
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. Expenses Overshadow Optimism for Kidney Failure Patients
3. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
4. Lowering Blood Protein Wont Help Kidney Patients
5. DaVita Teammates Bicycling 230 Miles for Kidney Disease Education
6. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
7. Metabolic syndrome heightens risk for development of uric-acid kidney stones
8. Nighttime Home Dialysis a Boon for Kidney Patients
9. New Survey Reveals Kidney Patients Concern About Medicare Policies
10. Nations Largest Dialysis Patient Organization Recognizes the Achievements of Patients and Leaders in Kidney Care
11. Kidney Awareness Time (KAT) Walk Raised Awareness and $400,000 for Kidney Education and Prevention Programs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Global MEMS Devices Medical Market Analysis 2016 - Forecast to ... The report contains up to date financial ... reliable analysis. Assessment of major trends with potential impact on ... dive analysis of market segmentation which comprises of sub markets, ...
(Date:6/23/2016)... , June 23, 2016 Research ... Pharma News Issue 52" report to their offering. ... in influenza treatment creates a favourable commercial environment for MedImmune ... growing patient base that will serve to drive considerable growth ... vaccine would serve to cap sales considerably, but development is ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
Breaking Medicine Technology: