Navigation Links
Kidney disease increases the risk of stroke in patients
Date:3/4/2009

OAKLAND, Calif., March 4, 2009 Chronic kidney disease increases the risk of stroke in patients with atrial fibrillation (AF), the most common type of heart arrhythmia, according to a new study by Kaiser Permanente researchers in the current online issue of Circulation.

It has long been known that chronic kidney disease is a risk factor for cardiovascular disease. This study is the first to look at whether chronic kidney disease independently increases risk of stroke in patients with AF. AF occurs when rapid, disorganized electrical signals in the heart's two upper chambers (the atria) cause the heart to contract fast and irregularly, they explain.

The finding is an important addition to the evidence base because atrial fibrillation affects more than 2.2 million Americans, particularly those 75 and older, and increases the risk of stroke nearly four fold, according to the researchers. In this study, the researchers looked at whether kidney disease increased the risk of ischemic stroke -- the most common kind of stroke that occurs when an artery to the brain in blocked.

The risk of stroke varies according to several demographic and clinical characteristics and current risk assessment strategies can be limited, according to the study's lead author Alan S. Go MD, Director of the Comprehensive Clinical Research Unit at the Kaiser Permanente Division of Research. "Our study suggests that kidney function may provide an additional clue about how to best assess stroke risk and decide upon the best prevention strategy for patients with AF," Go said.

The research is part of the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study, a decade-long, multi-center study looking at the risk factors for complications related to atrial fibrillation. In the ATRIA Study cohort of 13,535 adults with AF, the researchers assessed kidney function in two ways and found that a lower level of kidney function was associated with a graded, increased risk of ischemic stroke and blood clots that travel through the circulatory system, independent of known risk factors for AF. The magnitude of the associations for both measures of kidney function was in the range seen for other known stroke factors in AF patients, such as older age, heart failure, hypertension, diabetes, and being female.

Kidney disease may increases the risk of stroke in patients with AF by causing inflammation and stiffening of arteries. Also, decreased kidney function itself may be a marker for the build up of plaque in the arteries, explains Go.

In addition to the large, diverse sample of patients with AF, this study was strengthened by long-term longitudinal information on kidney function and the ability to characterize periods off anticoagulants, validating the occurrence of ischemic stroke, and the accounting for the presence of other known risk factors for stroke during follow up.


'/>"/>

Contact: Danielle Cass
Danielle.X.Cass@kp.org
510-267-5354
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. Expenses Overshadow Optimism for Kidney Failure Patients
3. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
4. Lowering Blood Protein Wont Help Kidney Patients
5. DaVita Teammates Bicycling 230 Miles for Kidney Disease Education
6. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
7. Metabolic syndrome heightens risk for development of uric-acid kidney stones
8. Nighttime Home Dialysis a Boon for Kidney Patients
9. New Survey Reveals Kidney Patients Concern About Medicare Policies
10. Nations Largest Dialysis Patient Organization Recognizes the Achievements of Patients and Leaders in Kidney Care
11. Kidney Awareness Time (KAT) Walk Raised Awareness and $400,000 for Kidney Education and Prevention Programs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) ... and Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton ... until Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice ... of cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Many families ... However, many long-term care insurance companies have a waiver for care if the client ... elimination period, when the family pays for care, is often waived, so the benefits ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, ... tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , PhD, ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
(Date:9/12/2017)... LAKES, N.J. , Sept. 12, 2017  Consumer reviews on ... Embrace Hearing as the number one company for hearing aids, ... ReSound™ and fifteen other brands. ... Embrace Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides ...
Breaking Medicine Technology: