Navigation Links
Kidney Trouble Short-Lived in Most Liver Transplant Patients

Study finds short-term dysfunction while awaiting operation rarely turns chronic

TUESDAY, May 6 (HealthDay News) -- Few patients who have short-term kidney dysfunction while awaiting a liver transplant develop severe kidney problems once they have their transplant, says a U.S. study.

An increasing number of patients have kidney dysfunction while awaiting liver transplantation, which has led to debate among transplant experts about which patients are likely to develop kidney dysfunction after liver transplant and should be considered for combined liver/kidney transplantation.

This kind of decision is extremely difficult due to the lack of a reliable predictive model and the increasing shortage of organs available for transplant, according to background information in the study, led by Ranjeeta Bahirwani, of the University of Pennsylvania.

The study included 60 people who had liver transplants between March 2000 and August 2005, and had serum creatinine of at least 1.5 mg/dl for at least two weeks prior to, and at the time of, transplantation.

The patients were followed for a median of 36 months after their transplant, and only eight of them had significant kidney dysfunction. Those who had kidney dysfunction for more than 12 weeks before transplant were at increased risk for severe post-transplant kidney problems.

Diabetes and serum creatinine level at the time of transplant were other major predictors of severe post-transplant kidney problems.

"Our data are reassuring that the vast majority of patients with pre-transplant renal insufficiency do not develop advanced stage 4 or 5 chronic kidney disease," after liver transplant, the study authors wrote.

Serious post-transplant kidney disease was particularly rare among patients whose pre-transplant serum creatinine was elevated for less than 12 weeks. The researchers suggested that elevated serum creatinine levels for more than 12 weeks before transplant, the presence of diabetes, and the serum creatinine value at the time of transplant could help identify patients who might be considered for combined liver-kidney transplantation.

The study was published in the May issue of Liver Transplantation.

More information

The American Liver Foundation has more about liver transplantation.

-- Robert Preidt

SOURCE: Liver Transplantation, news release, April 30, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. Expenses Overshadow Optimism for Kidney Failure Patients
3. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
4. Lowering Blood Protein Wont Help Kidney Patients
5. DaVita Teammates Bicycling 230 Miles for Kidney Disease Education
6. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
7. Metabolic syndrome heightens risk for development of uric-acid kidney stones
8. Nighttime Home Dialysis a Boon for Kidney Patients
9. New Survey Reveals Kidney Patients Concern About Medicare Policies
10. Nations Largest Dialysis Patient Organization Recognizes the Achievements of Patients and Leaders in Kidney Care
11. Kidney Awareness Time (KAT) Walk Raised Awareness and $400,000 for Kidney Education and Prevention Programs
Post Your Comments:
(Date:6/27/2016)... , ... June 27, 2016 , ... ... edge technology to revolutionize the emergency ambulance transport experience for the millions of ... of how Uber has disrupted the taxi industry through the use of technology. ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... ... ... crisis. Her son James, eight, was out of control. Prone to extreme mood shifts and ... him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife on ... say he was going to kill them. If we were driving on the freeway, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Key Pharma News Issue 52" report to their offering. ... need in influenza treatment creates a favourable commercial environment for ... and growing patient base that will serve to drive considerable ... flu vaccine would serve to cap sales considerably, but development ...
(Date:6/23/2016)... , June 23, 2016 Revolutionary ... Oticon , industry leaders in advanced audiology ... of Oticon Opn ™, the world,s first internet ... possibilities for IoT devices.      (Photo: ... introduces a number of ,world firsts,: , ...
Breaking Medicine Technology: