Navigation Links
Kidney Trouble Short-Lived in Most Liver Transplant Patients
Date:5/6/2008

Study finds short-term dysfunction while awaiting operation rarely turns chronic

TUESDAY, May 6 (HealthDay News) -- Few patients who have short-term kidney dysfunction while awaiting a liver transplant develop severe kidney problems once they have their transplant, says a U.S. study.

An increasing number of patients have kidney dysfunction while awaiting liver transplantation, which has led to debate among transplant experts about which patients are likely to develop kidney dysfunction after liver transplant and should be considered for combined liver/kidney transplantation.

This kind of decision is extremely difficult due to the lack of a reliable predictive model and the increasing shortage of organs available for transplant, according to background information in the study, led by Ranjeeta Bahirwani, of the University of Pennsylvania.

The study included 60 people who had liver transplants between March 2000 and August 2005, and had serum creatinine of at least 1.5 mg/dl for at least two weeks prior to, and at the time of, transplantation.

The patients were followed for a median of 36 months after their transplant, and only eight of them had significant kidney dysfunction. Those who had kidney dysfunction for more than 12 weeks before transplant were at increased risk for severe post-transplant kidney problems.

Diabetes and serum creatinine level at the time of transplant were other major predictors of severe post-transplant kidney problems.

"Our data are reassuring that the vast majority of patients with pre-transplant renal insufficiency do not develop advanced stage 4 or 5 chronic kidney disease," after liver transplant, the study authors wrote.

Serious post-transplant kidney disease was particularly rare among patients whose pre-transplant serum creatinine was elevated for less than 12 weeks. The researchers suggested that elevated serum creatinine levels for more than 12 weeks before transplant, the presence of diabetes, and the serum creatinine value at the time of transplant could help identify patients who might be considered for combined liver-kidney transplantation.

The study was published in the May issue of Liver Transplantation.

More information

The American Liver Foundation has more about liver transplantation.



-- Robert Preidt



SOURCE: Liver Transplantation, news release, April 30, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. Expenses Overshadow Optimism for Kidney Failure Patients
3. Katie Lee Joel to Conduct Cooking Demonstration for Local Patients With Chronic Kidney Disease
4. Lowering Blood Protein Wont Help Kidney Patients
5. DaVita Teammates Bicycling 230 Miles for Kidney Disease Education
6. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
7. Metabolic syndrome heightens risk for development of uric-acid kidney stones
8. Nighttime Home Dialysis a Boon for Kidney Patients
9. New Survey Reveals Kidney Patients Concern About Medicare Policies
10. Nations Largest Dialysis Patient Organization Recognizes the Achievements of Patients and Leaders in Kidney Care
11. Kidney Awareness Time (KAT) Walk Raised Awareness and $400,000 for Kidney Education and Prevention Programs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... 2017 , ... International Protein, a company based out of Australia that focuses ... January ECRM trade show in Hilton Head, SC. , International Protein was founded ... a line of products that would elevate her fitness regime. At this ECRM trade ...
(Date:1/20/2017)... ... January 20, 2017 , ... ... sugar-free alternative VW+ 002. The drinks have been produced in collaboration with Zlatan ... perform during your workout. , After a successful launch in Sweden last year, ...
(Date:1/20/2017)... ... 20, 2017 , ... “Code Word: Chocolate Biscuit”: a biographical account following a man who went ... creation of published author, Marlyn Ivey, born in Lynn Haven, Florida and at the age ... at 19 years of age, he joined the Navy and got married right out of ...
(Date:1/20/2017)... ... ... in Suffolk”: a story of love, secrets, and mystery. “Christmas in Suffolk” is ... works in a daycare and looks for inspiration in the local coffee shop as ... Seymour’s new book is an adventure of love and secrets. , After ...
(Date:1/20/2017)... ... ... “The Land of More and More”: a brilliant story for children and adults ... and achievable answer. “The Land of More and More” is the creation of published ... Indiana where he works with the children’s ministry department. , Michael says that ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , January 19, 2017 ... announced that the U.S. Food and Drug Administration (FDA) ... a New Drug Application (NDA) for SHP465, a long-acting, ... as a potential once-daily treatment for Attention-Deficit/Hyperactivity Disorder (ADHD). ... or around June 20, 2017, the designated Prescription Drug ...
(Date:1/19/2017)... -- Pfizer joins Astex, AstraZeneca, GlaxoSmithKline, ...   Major research investment to work ...   The Milner Therapeutics Institute today announces ... partner to the Milner Therapeutics Consortium. Pfizer has agreed ... of materials between industry and academia and allocation of ...
(Date:1/19/2017)... 2017 While various reports ... reducing the FDA,s regulatory strictness as a way ... drug industry, many of the leading biotech and ... and development of advanced drug treatments and therapies.  ... developments include:  Moleculin Biotech, Inc., (NASDAQ: ...
Breaking Medicine Technology: