Navigation Links
Kidney Donor's Sex Could Affect Women's Outcomes
Date:8/13/2009

Transplant failure, death risks rise if organ comes from deceased man, study finds,,,,

THURSDAY, Aug. 13 (HealthDay News) -- Female kidney recipients whose donated organ came from a deceased male face an increased risk for failure in the first year after their transplant, Canadian researchers have found.

The risk is short-term, though, and may stem from proteins on male donor cells, the researchers said. Their study found that the risk goes away after 10 years.

The researchers analyzed data on 117,877 adults who had kidney transplants in the United States between 1990 and 2004. All kidneys came from deceased donors. Within a year, transplant failure had occurred in 16,135 people, and 6,878 had died. Among the 97,906 people who were followed for up to 10 years after their transplant, there were 35,084 transplant failures and 22,566 deaths.

Compared with all other gender combinations, female recipients of male donor kidneys had a 12 percent greater risk of failure and a similar increased risk for death a year after the transplant. They had no increased risk for failure or death after 10 years.

The researchers, from the University of Toronto and University of British Columbia, said that H-Y antigens, derived from the male chromosome and not found in women, might cause an adverse immune response in women who receive kidneys from men who had died.

They recommended that "future research should examine the potential mechanisms underlying the H-Y effect in order to better understand the specific role of minor histocompatibility antigens in determining kidney allograft outcomes."

The study is published online in the Journal of the American Society of Nephrology.

More information

The National Kidney Foundation has more about kidney transplant.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, July 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The Kidney TRUST's Chronic Kidney Disease Rapid-Screening Program Hits 10,000
2. Low Birth Weight Might Raise Adult Kidney Disease Risk
3. Texas Kidney Community: CMS Authorization to Survey 22 New Dialysis Centers Excellent First Step Toward Opening Additional Pending Facilities, Creating More Local Jobs
4. For Some Kidney Patients, Home Dialysis Is Better
5. Fresh-Meat Additives May Be Dangerous for Kidney Patients
6. Baking Soda May Be Key Ingredient for Kidney Patients
7. Sunitinib Benefit Explored in Poor-Prognosis Kidney Cancer
8. Ochsner 1st in Louisiana to use Robotics in Living-Donor Kidney Transplant for Faster Recovery
9. Why African-Americans are at greater risk of hypertension and kidney disease
10. Johns Hopkins leads first 16-patient, multicenter domino donor kidney transplant
11. Kidney Paired Donation: 16 Patients, Four Hospitals, Four States
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidney Donor's Sex Could Affect Women's Outcomes
(Date:6/26/2016)... Carolina (PRWEB) , ... June 26, 2016 , ... ... of a new product that was developed to enhance the health of felines. The ... centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/24/2016)... ... , ... A recent article published June 14 on E Online ... on to state that individuals are now more comfortable seeking to undergo not only ... calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... June 24, 2016 Research ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural Health ... Structural electronics involves electronic and/or electrical ... structures, replacing dumb structures such as vehicle bodies ...
Breaking Medicine Technology: