Navigation Links
Kidney Donor's Sex Could Affect Women's Outcomes
Date:8/13/2009

Transplant failure, death risks rise if organ comes from deceased man, study finds,,,,

THURSDAY, Aug. 13 (HealthDay News) -- Female kidney recipients whose donated organ came from a deceased male face an increased risk for failure in the first year after their transplant, Canadian researchers have found.

The risk is short-term, though, and may stem from proteins on male donor cells, the researchers said. Their study found that the risk goes away after 10 years.

The researchers analyzed data on 117,877 adults who had kidney transplants in the United States between 1990 and 2004. All kidneys came from deceased donors. Within a year, transplant failure had occurred in 16,135 people, and 6,878 had died. Among the 97,906 people who were followed for up to 10 years after their transplant, there were 35,084 transplant failures and 22,566 deaths.

Compared with all other gender combinations, female recipients of male donor kidneys had a 12 percent greater risk of failure and a similar increased risk for death a year after the transplant. They had no increased risk for failure or death after 10 years.

The researchers, from the University of Toronto and University of British Columbia, said that H-Y antigens, derived from the male chromosome and not found in women, might cause an adverse immune response in women who receive kidneys from men who had died.

They recommended that "future research should examine the potential mechanisms underlying the H-Y effect in order to better understand the specific role of minor histocompatibility antigens in determining kidney allograft outcomes."

The study is published online in the Journal of the American Society of Nephrology.

More information

The National Kidney Foundation has more about kidney transplant.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, July 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The Kidney TRUST's Chronic Kidney Disease Rapid-Screening Program Hits 10,000
2. Low Birth Weight Might Raise Adult Kidney Disease Risk
3. Texas Kidney Community: CMS Authorization to Survey 22 New Dialysis Centers Excellent First Step Toward Opening Additional Pending Facilities, Creating More Local Jobs
4. For Some Kidney Patients, Home Dialysis Is Better
5. Fresh-Meat Additives May Be Dangerous for Kidney Patients
6. Baking Soda May Be Key Ingredient for Kidney Patients
7. Sunitinib Benefit Explored in Poor-Prognosis Kidney Cancer
8. Ochsner 1st in Louisiana to use Robotics in Living-Donor Kidney Transplant for Faster Recovery
9. Why African-Americans are at greater risk of hypertension and kidney disease
10. Johns Hopkins leads first 16-patient, multicenter domino donor kidney transplant
11. Kidney Paired Donation: 16 Patients, Four Hospitals, Four States
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidney Donor's Sex Could Affect Women's Outcomes
(Date:10/13/2017)... AR (PRWEB) , ... October 13, 2017 , ... ... with locations throughout Arkansas that offers insurance and financial preparation services, is providing ... the Rock City Rescue organization. , Rock City Rescue is a locally recognized ...
(Date:10/13/2017)... ... 13, 2017 , ... PurhealthRX , a leading Health and Nutrition Company, ... Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market by ... be easily incorporated into liquid products, while reducing costs to end users. , The ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans Bioscience ... the use of wearable and home sensors for real-time ... Early Signal Foundation, a nonprofit organization focused on disruptive ... provide an affordable analytical system to record and integrate ... ...
(Date:9/23/2017)... Pa. , Sept. 22, 2017 Janssen ... a complete response letter from the U.S. Food and ... seeking approval of sirukumab for the treatment of moderately ... letter indicates additional clinical data are needed to further ... moderately to severely active RA. ...
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
Breaking Medicine Technology: