Navigation Links
Kidney Donor's Sex Could Affect Women's Outcomes
Date:8/13/2009

Transplant failure, death risks rise if organ comes from deceased man, study finds,,,,

THURSDAY, Aug. 13 (HealthDay News) -- Female kidney recipients whose donated organ came from a deceased male face an increased risk for failure in the first year after their transplant, Canadian researchers have found.

The risk is short-term, though, and may stem from proteins on male donor cells, the researchers said. Their study found that the risk goes away after 10 years.

The researchers analyzed data on 117,877 adults who had kidney transplants in the United States between 1990 and 2004. All kidneys came from deceased donors. Within a year, transplant failure had occurred in 16,135 people, and 6,878 had died. Among the 97,906 people who were followed for up to 10 years after their transplant, there were 35,084 transplant failures and 22,566 deaths.

Compared with all other gender combinations, female recipients of male donor kidneys had a 12 percent greater risk of failure and a similar increased risk for death a year after the transplant. They had no increased risk for failure or death after 10 years.

The researchers, from the University of Toronto and University of British Columbia, said that H-Y antigens, derived from the male chromosome and not found in women, might cause an adverse immune response in women who receive kidneys from men who had died.

They recommended that "future research should examine the potential mechanisms underlying the H-Y effect in order to better understand the specific role of minor histocompatibility antigens in determining kidney allograft outcomes."

The study is published online in the Journal of the American Society of Nephrology.

More information

The National Kidney Foundation has more about kidney transplant.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, July 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The Kidney TRUST's Chronic Kidney Disease Rapid-Screening Program Hits 10,000
2. Low Birth Weight Might Raise Adult Kidney Disease Risk
3. Texas Kidney Community: CMS Authorization to Survey 22 New Dialysis Centers Excellent First Step Toward Opening Additional Pending Facilities, Creating More Local Jobs
4. For Some Kidney Patients, Home Dialysis Is Better
5. Fresh-Meat Additives May Be Dangerous for Kidney Patients
6. Baking Soda May Be Key Ingredient for Kidney Patients
7. Sunitinib Benefit Explored in Poor-Prognosis Kidney Cancer
8. Ochsner 1st in Louisiana to use Robotics in Living-Donor Kidney Transplant for Faster Recovery
9. Why African-Americans are at greater risk of hypertension and kidney disease
10. Johns Hopkins leads first 16-patient, multicenter domino donor kidney transplant
11. Kidney Paired Donation: 16 Patients, Four Hospitals, Four States
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidney Donor's Sex Could Affect Women's Outcomes
(Date:7/21/2017)... ... July 21, 2017 , ... ... a $5,000 grant from the C. R. Bard Foundation, Inc. to ... Somerset Hills , a service available through the nonprofit home care agency. Using ...
(Date:7/21/2017)... ... July 21, 2017 , ... West Dermatology is pleased to announce the newest ... 17, 2017, Ms. Vu will join West Dermatology’s large network of medical and cosmetic ... skin cancer , and more. She graduated from the University of Florida College of ...
(Date:7/20/2017)... , ... July 20, 2017 , ... TransPixel Volume 2 ... two clips in the FCPX timeline. This effect isolates horizontal and vertical lines of ... package contains either a rotating or flipping animation and can be changed using a ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... Houston, is pleased to announce their expansion to the Midwest with the establishment ... Alysse Hollis and Ronald Bell, and of counsels, John Peck and Robert Bruns, ...
(Date:7/20/2017)... ... July 20, 2017 , ... Doctors on Liens, the leading ... Horine Chiropractic , directed by Dr. Russell Horine, DC to their exclusive list ... run with Dr. Russell Horine serving as the clinic director and his son Dr. ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... 2017  Sysmex America, Inc., a leading provider ... as well as middleware information systems technology, today ... quality assurance easier and more risk free than ... for the innovation that it delivers to the ... assurance processes to a new level with automated, ...
(Date:7/10/2017)... , July 10, 2017  BDI Group ... and patient support services organization serving specialty pharmacies, ... the launch of four significant, value-added member programs ... insights, better manage reimbursement and improve access and ... factor therapies. ...
(Date:7/5/2017)... , July 5, 2017 Oramed ... www.oramed.com ), a clinical-stage pharmaceutical company focused on ... it has received approval from the Israel Securities Authority to ... (TASE). Oramed common stock will commence trading on the TASE ... the current market capitalization of the Company, it is expected ...
Breaking Medicine Technology: