Navigation Links
Ketamine can be a wonder drug for ER patients and their physicians
Date:7/23/2014

WASHINGTON -- For critically ill patients arriving at the emergency department, the drug ketamine can safely provide analgesia, sedation and amnesia for rapid, life-saving intubation, despite decades-old studies that suggested it raised intracranial pressure. The results of a systematic review of 10 recent studies of what many emergency physicians regard as a "wonder drug" are published online in Annals of Emergency Medicine "The Effect of Ketamine on Intracranial and Cerebral Perfusion Pressure and Health Outcomes: A Systematic Review."

"Apprehension for many years about ketamine's effects on blood pressure or injured brains inhibited its use for intubation, especially in North America compared to Europe, but our review shows those concerns are likely overblown," said lead study author Corinne Hohl, MD, of the Department of Emergency Medicine at Vancouver General Hospital in Vancouver, Canada. "In view of recent concerns about the potential negative effects of an alternative induction agent, etomidate, ketamine should be considered routinely in patients with life-threatening infections and more regularly for patients who have been 'found down,' or unconscious, before being transported to the ER."

The most significant worry about ketamine in critically ill patients has been its effect on intracranial and cerebral pressures. Studies comparing ketamine to sufentanil, fentanyl and other pharmacological agents (vasopressors, neuromuscular blocking agents, sedatives) found no differences in intracranial and cerebral pressures of patients who had been treated with them.

Studies assessing patients sedated with ketamine found no difference in neurological outcomes compared to patients sedated with fentanyl, sufentanil, remifentanil or etomidate. Length of stay in the hospital was unaffected by ketamine use. Patients sedated and intubated with ketamine were also no likelier to die than patients sedated by other agents.

"Given the potential benefit to emergency patients and their physicians, the debate on ketamine should be settled by a large, randomized controlled trial," said Dr. Hohl. "In the meantime, our review suggests what many emergency physicians already believe is true: Ketamine is safe and incredibly useful in critically ill patients who require rapid intubation."


'/>"/>
Contact: Julie Lloyd
jlloyd@acep.org
202-370-9292
American College of Emergency Physicians
Source:Eurekalert

Related medicine news :

1. Intranasal ketamine confers rapid antidepressant effect in depression
2. Ketamine improved bipolar depression within minutes
3. Wonderful Long sleeve prom dresses With Discounts At Cheapdressale.com
4. Wonderfully Raw Gourmet Launches Holiday Giveaway for Coco-Roons
5. InventHelp® Introduces the Wonder Comb - Modified Comb Promotes Scalp Health and Comfort (BFT-481)
6. Wonderwalls
7. Professional Help Can Do Wonders For People Who Are Suffering From Porn And Masturbation Addiction
8. Psoriatic arthritis patients need better screening, warns panel of experts
9. Dr. Jeremy Ueno Can Help Treat Patients That Have Failing Implants
10. LIVESTRONG Foundation and Patient Advocate Foundation Expand Partnership to Support the Needs of Cancer Patients and Survivors Nationwide
11. Advanced cancer patients can benefit from programs combining exercise, nutrition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... 2017 , ... Accreditation Commission for Health Care (ACHC) is ... (HCAOA). This agreement allows HCAOA members to receive special pricing on ACHC’s Home ... University (AU) educational resources that help prepare HCAOA members for ACHC Accreditation. , ...
(Date:4/28/2017)... ... ... Horizon Blue Cross Blue Shield of New Jersey (BCBSNJ) announced today that ... as “stable.” At the same time, the ratings agency cautioned that the company’s rating ... “capital adequacy” thresholds required for its strong rating. , “Horizon is committed to being ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... tubes . These lamps offer an instant energy-saving solution for F32T8 fluorescent lamps ... fixtures or disconnect ballasts. These 50,000 hour rated lamps utilize the existing electronic ...
(Date:4/28/2017)... ... ... The Texas Cord Blood Bank (TCBB), a program of nonprofit biomedical organization GenCure, ... at Renaissance in Edinburg for their outstanding efforts in collecting umbilical cord blood donations ... , “Women’s Hospital at Renaissance has been a collection partner for the TCBB since ...
(Date:4/28/2017)... Ca (PRWEB) , ... April 28, 2017 , ... Bill ... management industry in the coastal communities. After Tina Howe joined the team, the Bill ... happy employees, honest services at affordable rates, and giving back to the San Diego ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  IRIDEX Corporation (Nasdaq: ... financial results for the first quarter 2017 after the ... Company,s management team will host a corresponding conference call ... Investors interested in listening to the conference ... domestic callers or (703) 326-3030 for international callers, using ...
(Date:4/19/2017)... April 19, 2017 Global Prostate Cancer ... on the prostate cancer therapeutics market analyzes the ... Increasing prevalence of prostate cancer, launch of promising ... development of new drugs & therapeutic biological products, ... due to lesser side effects are some of ...
(Date:4/19/2017)... -- The Global Effective Microorganisms (EM) Market by ... covered and analysed the potential of Global Effective Microorganisms (EM) ... and growth factors. The report identifies and analyses the emerging ... global market. ... Tables and Figures, 6 Major Company Profiles, spread across 124 ...
Breaking Medicine Technology: