Navigation Links
Ketamine can be a wonder drug for ER patients and their physicians
Date:7/23/2014

WASHINGTON -- For critically ill patients arriving at the emergency department, the drug ketamine can safely provide analgesia, sedation and amnesia for rapid, life-saving intubation, despite decades-old studies that suggested it raised intracranial pressure. The results of a systematic review of 10 recent studies of what many emergency physicians regard as a "wonder drug" are published online in Annals of Emergency Medicine "The Effect of Ketamine on Intracranial and Cerebral Perfusion Pressure and Health Outcomes: A Systematic Review."

"Apprehension for many years about ketamine's effects on blood pressure or injured brains inhibited its use for intubation, especially in North America compared to Europe, but our review shows those concerns are likely overblown," said lead study author Corinne Hohl, MD, of the Department of Emergency Medicine at Vancouver General Hospital in Vancouver, Canada. "In view of recent concerns about the potential negative effects of an alternative induction agent, etomidate, ketamine should be considered routinely in patients with life-threatening infections and more regularly for patients who have been 'found down,' or unconscious, before being transported to the ER."

The most significant worry about ketamine in critically ill patients has been its effect on intracranial and cerebral pressures. Studies comparing ketamine to sufentanil, fentanyl and other pharmacological agents (vasopressors, neuromuscular blocking agents, sedatives) found no differences in intracranial and cerebral pressures of patients who had been treated with them.

Studies assessing patients sedated with ketamine found no difference in neurological outcomes compared to patients sedated with fentanyl, sufentanil, remifentanil or etomidate. Length of stay in the hospital was unaffected by ketamine use. Patients sedated and intubated with ketamine were also no likelier to die than patients sedated by other agents.

"Given the potential benefit to emergency patients and their physicians, the debate on ketamine should be settled by a large, randomized controlled trial," said Dr. Hohl. "In the meantime, our review suggests what many emergency physicians already believe is true: Ketamine is safe and incredibly useful in critically ill patients who require rapid intubation."


'/>"/>
Contact: Julie Lloyd
jlloyd@acep.org
202-370-9292
American College of Emergency Physicians
Source:Eurekalert

Related medicine news :

1. Intranasal ketamine confers rapid antidepressant effect in depression
2. Ketamine improved bipolar depression within minutes
3. Wonderful Long sleeve prom dresses With Discounts At Cheapdressale.com
4. Wonderfully Raw Gourmet Launches Holiday Giveaway for Coco-Roons
5. InventHelp® Introduces the Wonder Comb - Modified Comb Promotes Scalp Health and Comfort (BFT-481)
6. Wonderwalls
7. Professional Help Can Do Wonders For People Who Are Suffering From Porn And Masturbation Addiction
8. Psoriatic arthritis patients need better screening, warns panel of experts
9. Dr. Jeremy Ueno Can Help Treat Patients That Have Failing Implants
10. LIVESTRONG Foundation and Patient Advocate Foundation Expand Partnership to Support the Needs of Cancer Patients and Survivors Nationwide
11. Advanced cancer patients can benefit from programs combining exercise, nutrition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... , ... IndustryArchive.Org . is announcing a new way for B2B Sellers ... only pay for B.A.N.T. quality sales leads based on the Sellers decision to purchase ... reality that B2B buyers are controlling the sales process via the Internet and that ...
(Date:2/26/2017)... ... ... ODH, Inc.™ announced today it will exhibit and speak at the 10th ... Arlington, VA. ODH’s director of medical strategy, Candace Saldarini, M.D., will present on how ... management. , ODH will also have an exhibit booth where attendees may speak to ...
(Date:2/26/2017)... ... February 26, 2017 , ... Occupational pesticide ... with a specific LRRK2 mutation, according to a study released today at the ... evidence of a link between pesticides and incidence of sporadic PD through occupational ...
(Date:2/24/2017)... ... February 24, 2017 , ... HealthPostures, ... Go. Core benefits and advantages built into the home office sit stand solution ... and feel. Ability to gain the benefits embedded in the TaskMate Go are ...
(Date:2/24/2017)... ... February 24, 2017 , ... Only two months after the official release ... show in Cannes (France), XO Private has initiated a second print-run of its lavish ... almost a metre across when open, weighs in at more than six kilos, retails ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... DUBLIN , Feb. 24, 2017 Research ... Health Market Analysis & Trends - Industry Forecast to 2025" ... ... at a CAGR of around 23.8% over the next decade to ... analyzes the market estimates and forecasts for all the given segments ...
(Date:2/24/2017)... Research and Markets has announced the addition of ... to 2025" report to their offering. ... The Global Empty Capsules Market is poised to grow ... approximately $2.9 billion by 2025. This industry report analyzes ... as well as regional levels presented in the research scope. The study ...
(Date:2/24/2017)... Research and Markets has announced the addition of the "Dry ... offering. ... Dry eye Drugs Price Analysis and Strategies - 2016, provides drug pricing ... answers the following questions: What are the ... they positioned in the Global Dry eye market? What ...
Breaking Medicine Technology: