Navigation Links
Ketamine can be a wonder drug for ER patients and their physicians
Date:7/23/2014

WASHINGTON -- For critically ill patients arriving at the emergency department, the drug ketamine can safely provide analgesia, sedation and amnesia for rapid, life-saving intubation, despite decades-old studies that suggested it raised intracranial pressure. The results of a systematic review of 10 recent studies of what many emergency physicians regard as a "wonder drug" are published online in Annals of Emergency Medicine "The Effect of Ketamine on Intracranial and Cerebral Perfusion Pressure and Health Outcomes: A Systematic Review."

"Apprehension for many years about ketamine's effects on blood pressure or injured brains inhibited its use for intubation, especially in North America compared to Europe, but our review shows those concerns are likely overblown," said lead study author Corinne Hohl, MD, of the Department of Emergency Medicine at Vancouver General Hospital in Vancouver, Canada. "In view of recent concerns about the potential negative effects of an alternative induction agent, etomidate, ketamine should be considered routinely in patients with life-threatening infections and more regularly for patients who have been 'found down,' or unconscious, before being transported to the ER."

The most significant worry about ketamine in critically ill patients has been its effect on intracranial and cerebral pressures. Studies comparing ketamine to sufentanil, fentanyl and other pharmacological agents (vasopressors, neuromuscular blocking agents, sedatives) found no differences in intracranial and cerebral pressures of patients who had been treated with them.

Studies assessing patients sedated with ketamine found no difference in neurological outcomes compared to patients sedated with fentanyl, sufentanil, remifentanil or etomidate. Length of stay in the hospital was unaffected by ketamine use. Patients sedated and intubated with ketamine were also no likelier to die than patients sedated by other agents.

"Given the potential benefit to emergency patients and their physicians, the debate on ketamine should be settled by a large, randomized controlled trial," said Dr. Hohl. "In the meantime, our review suggests what many emergency physicians already believe is true: Ketamine is safe and incredibly useful in critically ill patients who require rapid intubation."


'/>"/>
Contact: Julie Lloyd
jlloyd@acep.org
202-370-9292
American College of Emergency Physicians
Source:Eurekalert

Related medicine news :

1. Intranasal ketamine confers rapid antidepressant effect in depression
2. Ketamine improved bipolar depression within minutes
3. Wonderful Long sleeve prom dresses With Discounts At Cheapdressale.com
4. Wonderfully Raw Gourmet Launches Holiday Giveaway for Coco-Roons
5. InventHelp® Introduces the Wonder Comb - Modified Comb Promotes Scalp Health and Comfort (BFT-481)
6. Wonderwalls
7. Professional Help Can Do Wonders For People Who Are Suffering From Porn And Masturbation Addiction
8. Psoriatic arthritis patients need better screening, warns panel of experts
9. Dr. Jeremy Ueno Can Help Treat Patients That Have Failing Implants
10. LIVESTRONG Foundation and Patient Advocate Foundation Expand Partnership to Support the Needs of Cancer Patients and Survivors Nationwide
11. Advanced cancer patients can benefit from programs combining exercise, nutrition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... On June 9, ... Benefit Claims Litigation seminar in Chicago, Illinois. She will present on: , ... cases litigated under ERISA involve claims for long-term disability benefits. This session ...
(Date:3/24/2017)... ... March 24, 2017 , ... Viewers who like to educate themselves on current ... practices, goods, services, and societal issues tend to appreciate and love the "Informed" series, ... of utilizing running events for causes around the world. , Running for ...
(Date:3/24/2017)... ... 2017 , ... Empower Brokerage, located in Southlake, Texas, intends ... , In February, 2017, Empower Brokerage introduced their new “Performance Partners” program to ... teach how to maximize their sales efforts, as well as how to best ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... with God #TruthwithGrace”: a devotional journal chronicling the writer’s path toward true communion ... to Walk with God #TruthwithGrace” is the creation of published author Lea Michelle ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Vintage and Harvest A Cultivation of ... college Bible teacher residing in North Carolina with his wife, Anna Marie. He and ... with six grandchildren. David is also the author of “Shadow and Substance.” , “Love, ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017 Research and Markets has announced ... - Industry Forecast to 2025" report to their offering. ... The Global Cryostat ... over the next decade to reach approximately $3.5 billion by 2025. ... for all the given segments on global as well as regional ...
(Date:3/23/2017)... DUBLIN , Mar. 23, 2017 Research ... Valve Devices Market: Analysis By Procedure, Replacement Procedure By Technique, Repair ... their offering. ... Global Heart Valve Devices Market is forecasted to grow at a ... heart valve devices is driven by rising aging population, growth in ...
(Date:3/23/2017)... and INDIANAPOLIS , March ... LLY ) and the William Sansum Diabetes Center ... of Latino people affected by diabetes through enhanced research, ... of diabetes and cardiovascular disease bears a disproportionate weight ... ," said David Kerr , M.D., FRCPE, ...
Breaking Medicine Technology: