Navigation Links
Kessler Foundation wins National MS Society grant to study prevention of cognitive decline

West Orange, NJ. December 6, 2012. The National Multiple Sclerosis (MS) Society awarded Victoria Leavitt, Ph.D., a $44,000 grant to study the effects of intellectual enrichment on cognitive decline in individual with multiple sclerosis. Participants in Dr. Leavitt's study will use iPads to engage in home-based activities such as reading, puzzle solving, and games for 12 weeks. Dr. Leavitt, a scientist in Neuropsychology and Neuroscience Research at Kessler Foundation, will correlate improvements in cognition with changes in neural network activity on fMRI. This one-year pilot project is titled, A Randomized Controlled Trial of Intellectual Enrichment to Build Cognitive Reserve in Multiple Sclerosis (NMSS grant # PP1854)

"This exciting study extends our innovative research of the cognitive effects of MS," said John DeLuca, PhD, VP of Research & Training. Prior work done at Kessler Foundation by Dr. James Sumowski showed for the first time the protective effect of cognitive reserve in people with MS. Dr. Sumowski, a research scientist in Neuropsychology and Neuroscience Research, found that individuals with MS who have a history of a mentally enriching lifestyle are better protected against cognitive decline (Neurology. 2010 June 15; 74(24): 1942󈞙). That cognitive reserve is an independent protective factor helps explain the lack of correlation between degree of brain atrophy and cognitive function.

That finding prompted Dr. Leavitt to investigate whether ongoing intellectual enrichment can boost cognitive reserve in people with MS. "Most of our cognitive reserve is developed early in life, during formal school years," explained Leavitt. "I am interested in whether adults with MS can build their reserve by engaging in intellectually stimulating activities, and whether that increase in reserve will protect against further cognitive decline. Moreover, if patients can achieve this using handheld devices like the iPad, this has the potential to change how we administer cognitive therapy. "

The pilot study will examine improvements in cognitive performance and correlations with changes in neural networks on fMRI. Rehabilitation interventions that strengthen neural networking in the brain are important in MS. "We believe that the brain may compensate for damage in one area by re-routing via other neural connections," noted Dr. Leavitt. "We expect that increasing cognitive reserve through intellectual enrichment will result in more efficient use of neural networks in individuals with MS."


Contact: Carolann Murphy
Kessler Foundation

Related medicine news :

1. Kessler Foundation marks 20th Anniversary of International Day of Persons with Disabilities
2. Dr. Deluca of Kessler Foundation receives medical excellence award for MS research
3. Kessler Foundations Dr. Chiaravalloti to speak at Virtual Reality Symposium at Walter Reed
4. Kessler Foundation scientists report negative impact of long-term caregiving on cognition
5. Kessler Foundation stroke expert receives $145,000 grant from Healthcare Foundation of New Jersey
6. Dr. Taub to give Estabrook Research Lecture at Kessler Foundation on Nov. 28
7. Kessler Foundation scientists awarded New Jersey grants for brain injury research
8. Kessler Foundation scientist garners best poster award for MS research
9. Dr. Chiaravalloti of Kessler Foundation comments on trends in rehabilitation research in MS
10. Kessler Foundation presents Brain Injury: From Research to Rebuilding Lives on Sept. 27-28
11. DeLuca of Kessler Foundation receives research award from American Psychological Association
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... ... private messaging application, announced today a significant contract that will provide its award-winning ... plans to build on the growing success of its Relay program, IBX Wire™, ...
(Date:10/13/2015)... ... 13, 2015 , ... e-con Systems Inc., a leading embedded design services company ... industry’s first RGB-IR pixel format camera with a USB 3.0 interface and e-CAM40_CUMI4682_MOD, ... of UVC USB 3.0 cameras, is based on the 1/3-inch OV4682 - a 4-megapixel ...
(Date:10/13/2015)... , ... October 13, 2015 , ... A child without ... why SmileCareClub , the leading remote invisible aligner system, has joined with ... otherwise go without it. For each aligner treatment plan purchased, SmileCareClub will donate one ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... Protein is ... the body, including muscle, bone, and blood. But how much protein does the average ... than it might seem, according to the October 2015 issue of Harvard Men's ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... targets the unique health needs of new moms. Postnatal Omega-3, which has ... ), utilizes Nordic Naturals’ exclusive, new, ultra-concentrated omega-3 oil. This breakthrough ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... LA JOLLA, Calif. , Oct. 13, 2015 /PRNewswire/ ... to revolutionize the practice of medicine, announced today the ... powered clinical research project that has the potential to ... San Diego, CA , at HLI,s ... open in 2016 in other US and International cities. ...
(Date:10/13/2015)... PARK, Calif. , Oct. 13, 2015 /PRNewswire/ ... of up to $100 million over five years ... Diseases (NIAID), part of the National Institutes of ... or treat acute or delayed effects of radiation ... , a division of SRI International will provide ...
(Date:10/13/2015)... MILFORD, Mass. , Oct. 13, 2015  SeraCare ... diagnostics manufacturers, announced today that the company,s precision medicine ... growing line of reference materials for next-generation sequencing (NGS)-based ... Mutation Mix-I (AF1-10) contains the same mixture of mutations ... the previously launched AF20 mix , but is ...
Breaking Medicine Technology: