Keryx Biopharmaceuticals' KRX-0401 (Perifosine) Data Selected for Oral Presentation at the 50th Annual Meeting of the American Society of ...( Paul Richardson MD to present res...),Health

Paul Richardson, MD to present results from Phase 1/2 Clinical Trial of Perifosine in combination with Bortezomib (+/- dexamethasone) on Tuesday, December 9, 2008 at 8:30am

NEW YORK, Nov. 10 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) today announced that data from its Phase 1/2 clinical trial of KRX-0401 (perifosine) has been selected for oral presentation at the upcoming 50th Annual Meeting of the American Society of Hematology (ASH), to be held in San Francisco from December 5-9, 2008.

The study entitled "Phase I/II Results of a Multicenter Trial of Perifosine (KRX-0401) + Bortezomib in Patients with Relapsed or Relapsed / Refractory Multiple Myeloma Who Were Previously Relapsed from or Refractory to Bortezomib," will be presented on Tuesday, December 9th at 8:30 am PST by Paul Richardson, M.D., Clinical Director of the Jerome Lipper Multiple Myeloma Center at the Dana-Farber Cancer Institute in Boston, MA.

This abstract became available for viewing earlier today on the American Society of Hematology website (http://www.hematology.org). There were 76 patients enrolled on study at the time of abstract submission, of which 57 were evaluable for response and are reported on within the abstract. An updated analysis will be presented at the conference. As detailed in the abstract, an overall response rate of 40% was seen in evaluable patients. A similar level of activity was seen in the subset of patients who were bortezomib-refractory. In the study, overall response rate is defined to include all MRs, PRs and CRs.

Paul Richardson, MD commented, "The addition of perifosine to bortezomib, with or without dexamethasone, has proved gen
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