Navigation Links
Keryx Biopharmaceuticals Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial of KRX-0401 (Perifosine) in the Treatment of Multiple Myeloma
Date:8/3/2009

ical products for the treatment of life-threatening diseases, including renal disease and cancer. Keryx is developing Zerenex(TM) (ferric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. Keryx is also developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 has demonstrated both safety and clinical efficacy in numerous adult and pediatric tumor types, both as a single agent and in combination with novel therapies. KRX-0401 also modulates a number of other key signal transduction pathways, including the JNK and MAPK pathways, which are pathways associated with programmed cell death, cell growth, cell differentiation and cell survival. KRX-0401 is currently in Phase 2 clinical development for multiple tumor types, with a Phase 3 in multiple myeloma, under SPA, pending commencement. Keryx is headquartered in New York City.

Cautionary Statement

Some of the statements included in this press release, particularly those anticipating future clinical trials and business prospects for KRX-0401, may be forward-looking statements that involve a number of risks and uncertainties. For those statements, we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. Among the factors that could cause our actual results to differ materially are the following: our ability to successfully and cost-effectively complete clinical trials for KRX-0401; the risk that the data (both safety and efficacy) from the Phase 3 study will not coincide with the d
'/>"/>

SOURCE Keryx Biopharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Keryx Biopharmaceuticals Inc. Regains Compliance With NASDAQ Listing Requirements
2. Keryx Biopharmaceuticals, Inc. Receives Extension for Nasdaq Listing Compliance
3. Keryx Biopharmaceuticals, Inc. Announces First Quarter 2009 Financial Results
4. Keryx Biopharmaceuticals, Inc. Requests an Appeal Hearing After Receiving Notice of Delisting From Nasdaq
5. Keryx Biopharmaceuticals Receives Nasdaq Notification
6. Keryx Biopharmaceuticals, Inc. Announces Third Quarter 2008 Financial Results
7. Keryx Biopharmaceuticals KRX-0401 (Perifosine) Data Selected for Oral Presentation at the 50th Annual Meeting of the American Society of Hematology
8. Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Third Quarter 2008 Financial Results on Tuesday, November 11, at 8:30 A.M. EST
9. Keryx Biopharmaceuticals, Inc. Announces Second Quarter 2008 Financial Results
10. Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) to be Presented at the Upcoming American Society of Hematology Meeting in Atlanta, Georgia
11. Presentation Time Correction: Keryx Biopharmaceuticals Presents at 12:00pm, ET Tomorrow (Oct. 3) at William Blair & Company Small-Cap Growth Stock Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... DC (PRWEB) August 28, 2014 ... to participate in the Association for Medical Education in ... Congressi in Milan, Italy August 30 – September 3, ... members of the international medical education community, share the ... which to strengthen resident physician placement in countries throughout ...
(Date:8/27/2014)... Recently, Skmen.com, a renowned garment manufacturer and retailer, has ... . The company has rich experience in making fashionable ... stock and ready to ship: celebrity bodycon dresses, mini ... and so forth. All of them are available in ... proud to announce the new collection of celebrity bodycon ...
(Date:8/27/2014)... When it comes to the bedroom, most homeowners ... without breaking the bank in the process. Regardless of whether ... set for the master bedroom or simply looking for something ... all during their Labor Day mattress promotion. , This ... mattresses for the home, while enjoying free delivery. Beyond bringing ...
(Date:8/27/2014)... Philadelphia, PA. Inc. magazine ranked ... 500 list, an exclusive ranking of the nation’s fastest-growing ... look at the most important segment of the economy ... early exposure as members of the Inc. 500 list ... , “Some of world’s greatest companies have had their ...
(Date:8/27/2014)... Millennium Treatment Group is proud to ... Mental Health Counselors Association (FMHCA). The addiction treatment facility ... sure to provide. , FMHCA is an organization dedicated ... mental health counselors. The organization was founded in 1976 ... and since then, it has served the state’s mental ...
Breaking Medicine News(10 mins):Health News:National Resident Matching Program International (NRMPI) to Exhibit at the 2014 AMEE Conference 2Health News:Skmen.com Unveils Its New Celebrity Bodycon Dresses for Its Loyal Customers 2Health News:Bedding Mart, Top Mattress Store in Broken Arrow Oklahoma, Announces a Huge Labor Day Sale 2Health News:Inc Magazine Unveils 33rd Annual List of America's Fastest-Growing Private Companies - the Inc. 500 2Health News:Millennium Treatment Group Sponsors Florida Mental Health Counselors Association 2
... Brand Innovation is offering a custom e-book, "Notes on Nursing" by Florence ... e-book is one in a series of e-books titled I ... C la s s i ... http://www.stinsonbrandinnovation.com/ebooks/SBI_NotesOnNursing.htm , "This is a way we celebrate the vital ...
... survey also finds unique mix of bacteria for each person ... "atlas" of bacterial life on and within the human body ... are a veritable United Nations of germs. , The scientists, ... they like to thrive on and within the body. They ...
... Picture it: One jerk in a bar spends the night ... the evening, the women aren,t receptive to even the nicest ... evolutionary theory. Males increase their fitness by acquiring more mates; ... and therein lies the conflict. Researchers at Binghamton University ...
... mimic parents, language, study finds , THURSDAY, Nov. 5 ... days old cry with intonation patterns that reflect the ... The conclusion drawn by German researchers is that fetuses ... trimester of pregnancy, laying the groundwork for learning language ...
... Seats still ... ... economy recovers from the recession, the province’s health care sector is just one industry taking ... the field and an increased need for nursing care from the province’s aging population. Anyone ...
... House Rules Committee announced that the "rule" for ... put forward by Rep. Brad Ellsworth, D-Ind. that the House ... language, House Democratic leaders hope to address the reluctance of ... , Dr. Charmaine Yoest, President and CEO of ...
Cached Medicine News:Health News:National Nurse Practitioner Week Recognized by STINSON Brand Innovation With Offer of 'Notes on Nursing' e-book 2Health News:Germs Mingle Most on Palms, Feet, Forearms 2Health News:Germs Mingle Most on Palms, Feet, Forearms 3Health News:Mom was right: Nice guys don't always finish last 2Health News:Fetus Learns Intonations of Mother's Tongue 2Health News:Fetus Learns Intonations of Mother's Tongue 3Health News:Practical Nursing Still a Growth Area in BC 2
(Date:8/27/2014)... , Aug. 27, 2014 Decision Resources Group ... the Memphis health system and ... clinical integration, with rivals Methodist Le Bonheur Healthcare and ... groups to coordinate patient care. In addition, a national ... the most health plan enrollment in the ...
(Date:8/27/2014)... By now, if you haven,t heard about the ALS Ice ... awareness campaign has brought this devastating disease to the forefront ... Million (and counting) for ALS. Every day, more and more ... as well. One such company, Acorn Stairlifts Inc., ... works with ALS sufferers and helps to provide solutions for ...
(Date:8/27/2014)... , Aug. 27, 2014 Reportlinker.com announces ... in its catalogue: Global Heart Valve ... http://www.reportlinker.com/p02316644/Global-Heart-Valve-Repair-and-Replacement-Market-2014-2018.html About Heart Valve ... the human heart which control the flow of ... with heart valve diseases such as valvular stenosis, ...
Breaking Medicine Technology:Memphis-area Health Systems Turn Attention to Clinical Integration 2Acorn Stairlifts Gives a Lift to the ALS Ice Bucket Challenge 2Global Heart Valve Repair and Replacement Market 2014-2018 2Global Heart Valve Repair and Replacement Market 2014-2018 3Global Heart Valve Repair and Replacement Market 2014-2018 4
... June 22 Walmart (NYSE: WMT ) and Eli ... to provide an affordable insulin option for people with diabetes.   , ... Beginning in mid-September, Lilly,s Humulin ® ... under the dual-branded name Humulin ® ReliOn ®, including 10 mL ...
... Emdeon Inc. (NYSE: EM ), a leading provider ... acquisition of Chapin Revenue Cycle Management, LLC ("Chapin"). Based in ... revenue cycle services including accounts receivable management, medical denials, appeals and ... , ...
Cached Medicine Technology:Walmart, Lilly Team Up to Provide Human Insulin to People With Diabetes 2Walmart, Lilly Team Up to Provide Human Insulin to People With Diabetes 3Walmart, Lilly Team Up to Provide Human Insulin to People With Diabetes 4Walmart, Lilly Team Up to Provide Human Insulin to People With Diabetes 5Emdeon Acquires Chapin to Enhance Provider-Focused Payment Integrity 2Emdeon Acquires Chapin to Enhance Provider-Focused Payment Integrity 3Emdeon Acquires Chapin to Enhance Provider-Focused Payment Integrity 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: