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Keppra XR(TM) Offers Convenient Dosing For People With Partial Onset Seizures
Date:11/5/2008

h other AEDs were somnolence, asthenia, infection, and dizziness.

Keppra XR(TM) should be gradually withdrawn to minimize the potential of increased seizure frequency.

Dosing must be individualized according to the patient's renal function status. In patients with end-stage renal disease on dialysis, it is recommended that immediate-release Keppra(R) be used instead of Keppra XR(TM). Please see Keppra.com for Keppra(R) immediate-release tablets full prescribing information.

For full prescribing information, please see http://www.KeppraXR.com.

In order to ensure patient access to this valuable medication in the U.S., UCB is initiating a co-pay support program. For more information, contact U.S. UCB Medical Information at 1-866-822-0068 (press 9).

Important Safety Information about Vimpat(R) in the U.S.

AEDs, including Vimpat(R), increase the risk of suicidal behavior and ideation in patients taking these drugs. Patients should be monitored for the emergence or worsening of depression, suicidal thoughts, or behavior and/or any unusual changes in mood or behavior. Patients should be advised that Vimpat(R) may cause dizziness, ataxia, and syncope. Caution is advised for patients with known cardiac conduction problems, who are taking drugs known to induce PR interval prolongation, or with severe cardiac disease. In patients with seizure disorders, Vimpat(R) should be gradually withdrawn to minimize the potential of increased seizure frequency. Multiorgan sensitivity reactions have been reported with anticonvulsants. If this reaction is suspected, Vimpat(R) should be discontinued and an alternative treatment started.

About Epilepsy

Epilepsy is a chronic neurological disorder affecting approximately three million people in the U.S. -- making it more common than multiple sclerosis and Parkinson's disease combined. It is caused by abnormal, excessive electrical dischar
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