Navigation Links
Kaiser Permanente -- Group Health study shows depression worsens HIV treatment

December 20, 2007 (Oakland, Calif.) The largest study to examine the effect of depression on HIV treatment found that depression significantly worsens a patients adherence to highly active antiretroviral therapy and clinical measures, but that effective antidepressant medication can reverse this outcome, according to a study by the Kaiser Permanente Division of Research and the Group Health Cooperative published in the current online issue of the Journal of Acquired Immune Deficiency Syndromes (JAIDS).

The study looked at 3,359 HIV-infected patients from seven Kaiser Permanente regions nationwide and Group Health in 2000 to 2003 to measure the effects of depression -- with and without selective serotonin reuptake inhibitors (SSRI) use -- on adherence and changes in viral and immunologic control in patients starting a new highly active antiretroviral therapy (HAART) regimen.

The researchers studied the patients HAART adherence, viral loads, and changes in CD4 T-cell counts over a 12-month period. The study found that depressed patients -- 42 percent of the patient group -- had a lower adherence rate and worse viral therapy response compared to non-depressed patients. But depressed patients who were prescribed SSRI medication and adhered to it had the same outcomes as non-depressed patients.

The take-home point of this study is that depression carries a worse prognosis for HAART in HIV patients. However, we also found that SSRIs can reverse this and improve outcomes for HIV-depressed patients, said Michael A. Horberg, MD, MAS, FACP, Director of HIV/AIDS for Kaiser Permanente and the lead author on the study. HIV and depression often go hand in hand. If you are HIV-infected, you should be screened regularly for depression, and if you are depressed and you are going to go on HAART, its very worthwhile to treat your depression.


Contact: Danielle Cass
Kaiser Permanente Division of Research

Page: 1

Related medicine news :

1. Webcast Alert: Kaiser Permanente Residency Program Open House
2. Kaiser Permanente Achieves Climate Action Leader Status
3. Kaiser Permanente study: Alcohol amount, not type -- wine, beer, liquor -- triggers breast cancer
4. Kaiser Permanente Study Shows Alcohol Consumption - No Matter Beverage Type - Linked to Breast Cancer Risk
5. Kaiser Permanente Study Shows One in Seven Women are Depressed Before, During, or After Pregnancy
6. Kaiser Permanente Named Green Electronics Champion by EPA, Green Electronics Council
7. WellBound Teams With Kaiser Permanente to Open New Self-Care Dialysis Center in Sacramento, CA
8. Kaiser Permanente Joins With Top Health Care Groups to Create Healthier Hospital Environments
9. Kaiser Permanente study shows electronic medical records and outreach improve osteoporosis care
10. Kaiser Permanente CEO Receives Diversity Leadership Award
11. Kaiser Permanente and Golden State Warriors Team Up to Fight Childhood Obesity
Post Your Comments:
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... Forecast to 2022" report to their offering. ... date financial data derived from varied research sources to present ... impact on the market during the next five years, including ... sub markets, regional and country level analysis. The report provides ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
Breaking Medicine Technology: