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KLRI Releases 3rd Annual Report On Year's Top Longevity Research Findings
Date:5/12/2009

rs, ages 25 to 45, assigned to either restrict their calories by 25 percent or be part of a control group, has already produced some interesting data. For instance, calorie restriction reduces insulin levels, core body temperature, energy expenditure and DNA damage. It can also increase cellular resistance to stress proteins.

Hormones and aging. While the Kronos Early Estrogen Prevention Study (KEEPS), designed to evaluate the effect of estrogen on heart disease in younger, postmenopausal women continues, ancillary studies underway could provide interesting data on other topics. These include menopause and age-related skin changes and the effects of estrogen on blood cell function and the formation of blood clots. Meanwhile, KLRI's TEAAM (Testosterone Effects on Atherosclerosis in Aging Men) completed recruitment and is engaged in the research necessary to track the effect of supplemental testosterone on a variety of age-related markers. While both trials will examine the role of hormones in cognitive function, research published this year from other studies found no effects from either a low dose of estrogen or supplemental testosterone on cognition.

The Longevity Dividend. The Longevity Dividend is based on the theory that, if we can intervene scientifically to slow the aging process and delay the onset of age-related diseases, trillions of dollars now spent on health care could be redirected to schools, energy, jobs, infrastructure -- the "dividend." A group of leading scientists hopes to convince the federal government to change medical research funding from its focus on individual diseases to a focus that recognizes the importance of research into the underlying biology of aging. Only then, they contend, can the Longevity Dividend become a reality.

KLRI Research in 2008/2009. In addition to KLRI's longer-range studies on the possible cardio-protective effects of hormone replaceme
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SOURCE Kronos Longevity Research Institute
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