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K-State scientist receives grant from National Institutes of Health to research cataracts
Date:7/14/2009

measure protein interactions in a normal eye versus a cataractous eye. This process is normally used to study the interaction of smaller organic compounds; however Takemoto's lab will be the first to use it to study the interactions of proteins.

In microequilibrium dialysis, a mixture of two different types of proteins is put into one chamber, separated from another chamber by a filter that will only allow the passage of one type of protein. Over time, the protein concentrations in the chambers equalize, and if an interaction occurred, then the proteins should bind to one another.

"This technique allows us to both detect and quantitate possible changes in these interactions for the first time, under true equilibrium conditions," Takemoto said. "This study will establish the presence of interactions and will determine whether these interactions are altered during cataractogenesis."


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Contact: Larry Takemoto
takemlj@k-state.edu
785-532-6636
Kansas State University
Source:Eurekalert

Page: 1 2

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