Navigation Links
K-State engineers create DNA sensors that could identify cancer using material only one atom thick
Date:4/13/2009

Kansas State University engineers think the possibilities are deep for a very thin material.

Vikas Berry, assistant professor of chemical engineering, is leading research combining biological materials with graphene, a recently developed carbon material that is only a single atom thick.

"The biological interfacing of graphene is taking this material to the next level," Berry said. "Discovered only four years ago, this material has already shown a large number of capabilities. K-Staters are the first to do bio-integrated research with graphene."

To study graphene, researchers rely on an atomic force microscope to help them observe and manipulate these single atom thick carbon sheets.

"It's a fascinating material to work with," Berry said. "The most significant feature of graphene is that the electrons can travel without interruptions at speeds close to that of light at room temperature. Usually you have to go near zero Kelvin -- that's about 450 degrees below zero Fahrenheit -- to get electrons to move at ultra high speeds."

One of Berry's developments is a graphene-based DNA sensor. When electrons flow on the graphene, they change speed if they encounter DNA. The researchers notice this change by measuring the electrical conductivity. The work was published in Nano-Letters.

"Most DNA sensors are optical, but this one is electrical," Berry said. "We are currently collaborating with researchers from Harvard Medical School to sense cancer cells in blood."

Another area he is exploring is loading graphene with antibodies and flowing bacteria across the surface.

"Most researchers focus on pristine graphene, but we're making it dirty," he said.

Berry and Nihar Mohanty, a graduate student in chemical engineering, used a type of bacteria commonly found in rice and interfaced it with graphene. They found that the graphene with tethered antibodies will wrap itself around an individual bacterium, which remains alive for 12 hours.

Berry said that possible applications include a high-efficiency bacteria-operated battery, where by using geobater, a type of bacteria known to produce electrons, can be wrapped with graphene to produce electricity. The research was presented at the annual American Physical Society conference in Pittsburgh and the American Institute for Chemical Engineers conference in Philadelphia.

"Materials science is an incredible field with several exploitable quantum effects occurring at molecular scale, and biology is a remarkable field with a variety of specific biochemical mechanisms," Berry said. "But for the most part the two fields are isolated. If you join these two fields, the possibilities are going to be immense. For example, one can think of a bacterium as a machine with molecular scale components and one can exploit the functioning of those components in a material device."

For his doctoral research, Berry used bacteria to make a humidity sensor.

"That was only possible through combining materials science with biological science," he said.

Another area of his current research is compressing and stretching molecular-junctions between nanoparticles. Berry said that his group has developed a molecular-spring device where they can compress and stretch molecules, which then act like springs, allowing researchers to study how they relax back. He said that this technology could be used to create molecular-timers in which the spring action from a decompressed molecule on a chip could trigger a circuit, for instance.

Berry said for stretching the molecules, Kabeer Jasuja, a doctoral student in chemical engineering, came up with the idea to place the device on a centrifuge to stretch the molecules with centrifugal force.

The work was published in the journal Small.


'/>"/>

Contact: Vikas Berry
vberry@k-state.edu
785-532-5519
Kansas State University
Source:Eurekalert  

Related medicine news :

1. Expert on Emerging Infectious Zoonotic Diseases Joining K-State as a Regents Distinguished Professor
2. Professionals in bioscience, food-related industries turn to K-State
3. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
4. K-State Researchers Predict That an Outbreak of Foot-And-Mouth Disease Could Cost Kansas Nearly a Billion Dollars
5. K-State Trauma Researcher Says Being Prepared, Taking Action Are Vital in Preventing Tragedies Like the One at NIU
6. K-State and Kansas Health Foundation Team Up to Promote One Health Kansas
7. K-State Veterinarian Discusses Treating Dogs With Cushings Disease
8. K-State helps nursing home staff become comfortable with residents sexual expression
9. K-State Psychologist Studies Ways to Improve Soldiers Work-Life Relationship
10. Engineers developing new cements to heal spinal fractures
11. SMRT Architects and Engineers Selected to Design New $115M Digital X-Ray Manufacturing Facility for GE Healthcare
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
K-State engineers create DNA sensors that could identify cancer using material only one atom thick
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
(Date:10/12/2017)... ... 2017 , ... Information about the technology: , Otomagnetics has ... prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin ... cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, ... relay – Miles by Moonlight to raise money for the American Heart Association Heart ... , Teams will work together to keep their treadmills moving for 5 hours. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vohra Chief Medical ... to physician colleagues, skilled nursing facility medical directors and other clinicians at various ... Wound Care." , "At many of these conferences we get to educate other ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, ... 8th Day Software and Consulting, LLC , and named ... 8th Day Software, based in Tennessee , ... 8th Day expands EnvoyHealth,s service offerings for health care ... "In an interoperable ...
(Date:10/2/2017)... 2017  AllianceRx Walgreens Prime, the combined central specialty ... pharmacy benefit manager Prime Therapeutics LLC (Prime), today officially ... the unveiling of new signage at its headquarters in ... at a few other company-owned facilities across the country. ... some of whom will begin to see the AllianceRx ...
Breaking Medicine Technology: