BOSTONThe Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.
The Joint Center brings together expertise and resources in state-of-the-art capabilities including DNA sequencing and other tumor molecular profiling technologies, pathology, radiology, surgery, computational interpretation, and new tumor model systems; and reinforces the joint commitment to pursue advances in cancer genetics to improve patient care. It will be headquartered at Dana-Farber.
"This center will allow us to be optimally positioned to answer the big questions in cancer genetics, especially as they affect clinical decision-making," said Levi Garraway, MD, PhD, associate professor of medicine at Dana-Farber and the new center's director. "We seek to understand which genetic and other molecular alterations predict how tumors will respond to targeted drugs, why some patients become resistant to drugs, and what that means about the treatments that should be tried next."
"Our mission is to accelerate the development of personalized therapies that achieve long-term disease control and, eventually, the cure of many patients with advanced cancer," Garraway said. The terms "precision" and "personalized" both refer to an emerging form of cancer care that identifies genetic changes within a patient's tumor that can be used to predict how it will behave and which drugs will be most effective against it.
"The center is creating a new capability to use these huge resources in sequencing and pathology and making sure the data gets to caregivers to help customize treatment," said Edward Benz, Jr., MD, president of Dana-Farber.
|Contact: Anne Doerr|
Dana-Farber Cancer Institute