Navigation Links
Johns Hopkins scientists begin first-of-its-kind research to create blood platelets from stem cells
Date:8/3/2011

Johns Hopkins scientists have launched a pioneering research program to create, for the first time, human platelet cells from stem cells in order to study inherited blood clotting abnormalities ranging from clots that cause heart attacks and stroke to bleeding disorders. The study is funded by a $9 million grant from the National Institutes of Health (NIH) as part of a nationwide initiative to examine how genetic variations cause heart, lung and blood diseases.

One goal of the Hopkins research is to increase understanding of how genes regulate the function of platelets, which are the sticky cells in blood that are important to stop excessive bleeding. The researchers will also investigate how genetic variations can affect a person's responsiveness to aspirin and other medications that are designed to prevent clotting, in order to find new ways to prevent and treat abnormal clotting. Current anticoagulants, or "blood thinner" medications that are essential to prevent life-threatening complications from some heart or vascular diseases, are not always effective for individuals with certain genetic variations.

The other key aspect of the research will be to develop the technical capacity to produce large numbers of blood platelets from a single individual's blood sample. That way, patients who need platelet transfusions, such as those whose platelets were wiped out following chemotherapy, would be able to be transfused with their own platelets without the risk of rejection that comes with receiving platelets donated from others.

"We will work to develop a completely new approach to generating blood cells for people who are desperately in need of chronic infusions," says Lewis Becker, M.D., professor of medicine and cardiologist at the Johns Hopkins University School of Medicine, who is the co-principal investigator of the study, called Functional Genomics of Platelet Aggregation Using iPS and Derived Megakaryocites.

To begin
'/>"/>

Contact: Ellen Beth Levitt
eblevitt@jhmi.edu
410-955-5307
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Johns Hopkins researchers discover how some breast cancers alter their sensitivity to estrogen
2. Informed-consent forms should be shortened, simplified, Johns Hopkins bioethicists confirm
3. More focus needed on mental health triage in disaster preparedness, Johns Hopkins bioethicists urge
4. Johns Hopkins School of Medicine grants $5 million to study cognitive disorders
5. Johns Hopkins School of Medicine postdoctoral fellows win awards
6. Johns Hopkins researchers develop safer way to make induced pluripotent stem cells
7. Johns Hopkins scientists crack genetic code for form of pancreatic cancer
8. Hospital shootings rare, but rate of other assults high, Johns Hopkins researchers find
9. Johns Hopkins researchers turn off severe food allergies in mice
10. Kilimani Sesame has positive impact on children in Tanzania: Johns Hopkins University study
11. Pro Ana Versus Pro Recovery Sites: New Study by Johns Hopkins and Stanford University raises concerns.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... CA (PRWEB) August 27, 2014 Reviewing ... policies will now be easier for the public when ... prices that are promoted in all 50 states in ... , The different insurers that are generating the ... it possible for adults to use the programmed system ...
(Date:8/27/2014)... Angeles, CA (PRWEB) August 27, 2014 ... to require a consumer to present personal information before ... changing the way that life insurance quotes are distributed ... , The term plans that an adult has ... provided by known U.S. companies. The system for quotation ...
(Date:8/27/2014)... 2014 The Latinos In Action Festival ... 7th at the Florida State Fair Grounds from 9am ... art and cultures from around the world. Latinos in ... Go Smart Mobile and Univision Mobile, a service provided ... an estimate of 4,000 people from different backgrounds, cultures ...
(Date:8/27/2014)... WEDNESDAY, Aug. 27, 2014 (HealthDay News) -- Young adults ... "hyper-connected" networks in their brain, researchers are reporting. ... lead to new ways to predict, prevent and treat ... Chicago researchers. The researchers conducted brain scans on ... in their teen years, and a control group of ...
(Date:8/27/2014)... known to play a key role in inflaming blood ... A new study at UCLA demonstrates that they may ... that narrows the small blood vessels in the lungs. ... a peptide mimicking part of the main protein in ... reduce the production of oxidized lipids in pulmonary hypertension. ...
Breaking Medicine News(10 mins):Health News:Home Insurance Prices for All 50 States Now Supplied at Consumer Insurance Portal Online 2Health News:Life Insurance Quotes for Term Policies Now Found at Insurer Website Online 2Health News:Marc Anthony to Perform at "Nieves Productions" Latinos in Action Festival 2Health News:Study: Young Adults Who Had Depression Have 'Hyper-Connected' Brain Networks 2Health News:Protein in 'good cholesterol' may be a key to treating pulmonary hypertension 2
... has affirmed its ratings and Stable outlook for ... http://www.newscom.com/cgi-bin/prnh/20081024/PROASSURANCELOGO )In announcing its decision, Fitch ... "...considers the solid financial condition of PRA,s ... financial and operating flexibility, and highly experienced management team. ...
... March 5 Stephen J. Ubl, president ... released the following statement today regarding the re-introduction of ... not in any way improve patient safety. It will, ... a chilling effect on medical innovation, create more lawsuits ...
... Spheris, a leading global provider of clinical documentation technology ... financial results for the fourth quarter ended December 31, 2008. ... quarter of 2008 after the close of market trading on ... on Thursday, March 26, 2009, at 8 a.m. CT. ...
... are prepared for infant,s crying bouts can maintain better ... -- An educational program for parents can help prevent ... to American and Canadian studies. , "Typically, crying ... that new parents receive information and learn coping strategies," ...
... Harvard Health Letter , in consultation with the doctors on its editorial ... society--and perhaps yourself--some money , ... Boston, MA (PRWEB) March 5, 2009 ... care spending is brought under control. Moreover, even people with good health ...
... On Thursday, March 12, the Aspen Health Stewardship ... that have come together in support of a roadmap ... care system.Members of the coalition, which includes patient groups, ... we can achieve a healthier America by adopting a ...
Cached Medicine News:Health News:Fitch Affirms ProAssurance's Rating and Stable Outlook 2Health News:Fitch Affirms ProAssurance's Rating and Stable Outlook 3Health News:AdvaMed Response to the Medical Device Safety Act 2Health News:Preventing Shaken Baby Syndrome 2Health News:Runaway Health Care Costs: 12 Ways You Can Rein Them in, from the Harvard Health Letter 2Health News:Runaway Health Care Costs: 12 Ways You Can Rein Them in, from the Harvard Health Letter 3Health News:Aspen Institute to Introduce Roadmap for Responsible Health Care Reform, New Coalition To Call For Sustainable Improvements 2
(Date:8/27/2014)... , Aug. 27, 2014 Pulse Systems, ... (EHR) , Practice Management , and Revenue Cycle ... known business practices performed by some RCM vendors, at UBM ... PA on September 19-20, 2014.  ... will return in September with a new session encouraging practices ...
(Date:8/27/2014)... Aug. 27, 2014 Sihuan Pharmaceutical Holdings ... "Company"), a leading pharmaceutical company with the largest ... China,s prescription drug market, today announced ... its subsidiaries (collectively the "Group") for the six ... Financial HighlightsFor the Six months ended 30 ...
(Date:8/27/2014)... BOSTON , Aug. 27, 2014  Columbia Laboratories, ... Company"), a provider of pharmaceutical development, clinical trial manufacturing, ... industry, today announced that it will participate at the ... Investment Conference, to be held in New ... conference at 11:15am on September 9, 2014 at the ...
Breaking Medicine Technology:Pulse Systems Presents the Truth about Revenue Cycle Management Services at Practice Rx 2Pulse Systems Presents the Truth about Revenue Cycle Management Services at Practice Rx 3Pulse Systems Presents the Truth about Revenue Cycle Management Services at Practice Rx 4Sihuan Pharmaceutical Announces 2014 Interim Results 2Sihuan Pharmaceutical Announces 2014 Interim Results 3Sihuan Pharmaceutical Announces 2014 Interim Results 4Sihuan Pharmaceutical Announces 2014 Interim Results 5Sihuan Pharmaceutical Announces 2014 Interim Results 6Sihuan Pharmaceutical Announces 2014 Interim Results 7
... (Nasdaq: VICL ) announced today the receipt of ... based on Merck,s planned initiation of a Phase I clinical ... candidate vaccine is based on Vical,s DNA gene delivery technology ... subject of separate license agreement. , , ...
... Abnormalities in auditory and language processing may be ... magnetoencephalography (MEG), according to a study presented today at ... America (RSNA). , , ... associated with electrical brain activity," said Timothy Roberts, Ph.D., ...
Cached Medicine Technology:Vical Receives Milestone Payment from Merck & Co., Inc. Triggered by Planned Initiation of Investigational Cancer DNA Vaccine Trial 2Brain Waves Show Sound Processing Abnormalities in Autistic Children 2Brain Waves Show Sound Processing Abnormalities in Autistic Children 3
The Needle Loading Platform / Shield is designed to provide superior operator shielding during the loading of prostate implant needles with iodine or palladium seeds. It is constructed of 3/8" alumin...
... Sorting Tray is designed to allow you to ... also be sorted according to source strength. Each ... and can easily hold over 100 seeds. The ... will easily fit into all autoclaves. The tray ...
... designed to pull prostate implant seeds and spacers into ... clear tube tip by placing a finger over a ... The prescribed sequence of seeds and spacers is visually ... into the needle. These seeds and spacers are then ...
MT-BT-5001-25 prostate seeding needle (set of 25 unloaded needles).,MT-BT-5001-P prostate seeding needle, pre-plugged and pre-sterilized, unloaded or for use with MEDTECs ASAP™ pre-load seeding...
Medicine Products: