Navigation Links
Johns Hopkins scientists begin first-of-its-kind research to create blood platelets from stem cells
Date:8/3/2011

Johns Hopkins scientists have launched a pioneering research program to create, for the first time, human platelet cells from stem cells in order to study inherited blood clotting abnormalities ranging from clots that cause heart attacks and stroke to bleeding disorders. The study is funded by a $9 million grant from the National Institutes of Health (NIH) as part of a nationwide initiative to examine how genetic variations cause heart, lung and blood diseases.

One goal of the Hopkins research is to increase understanding of how genes regulate the function of platelets, which are the sticky cells in blood that are important to stop excessive bleeding. The researchers will also investigate how genetic variations can affect a person's responsiveness to aspirin and other medications that are designed to prevent clotting, in order to find new ways to prevent and treat abnormal clotting. Current anticoagulants, or "blood thinner" medications that are essential to prevent life-threatening complications from some heart or vascular diseases, are not always effective for individuals with certain genetic variations.

The other key aspect of the research will be to develop the technical capacity to produce large numbers of blood platelets from a single individual's blood sample. That way, patients who need platelet transfusions, such as those whose platelets were wiped out following chemotherapy, would be able to be transfused with their own platelets without the risk of rejection that comes with receiving platelets donated from others.

"We will work to develop a completely new approach to generating blood cells for people who are desperately in need of chronic infusions," says Lewis Becker, M.D., professor of medicine and cardiologist at the Johns Hopkins University School of Medicine, who is the co-principal investigator of the study, called Functional Genomics of Platelet Aggregation Using iPS and Derived Megakaryocites.

To begin
'/>"/>

Contact: Ellen Beth Levitt
eblevitt@jhmi.edu
410-955-5307
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Johns Hopkins researchers discover how some breast cancers alter their sensitivity to estrogen
2. Informed-consent forms should be shortened, simplified, Johns Hopkins bioethicists confirm
3. More focus needed on mental health triage in disaster preparedness, Johns Hopkins bioethicists urge
4. Johns Hopkins School of Medicine grants $5 million to study cognitive disorders
5. Johns Hopkins School of Medicine postdoctoral fellows win awards
6. Johns Hopkins researchers develop safer way to make induced pluripotent stem cells
7. Johns Hopkins scientists crack genetic code for form of pancreatic cancer
8. Hospital shootings rare, but rate of other assults high, Johns Hopkins researchers find
9. Johns Hopkins researchers turn off severe food allergies in mice
10. Kilimani Sesame has positive impact on children in Tanzania: Johns Hopkins University study
11. Pro Ana Versus Pro Recovery Sites: New Study by Johns Hopkins and Stanford University raises concerns.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/21/2014)... 21, 2014 The number of Mirena ... consolidated litigation underway in New Jersey, Bernstein Liebhard LLP ... 1,375 claims involving the birth control IUD have now ... were filed by women who allege spontaneous migration of ... uterine perforations and other complications they were inadequately warned ...
(Date:12/21/2014)... December 21, 2014 SCI ... the issues and systemic barriers for disabled athletes with ... Champion. Scheidies has a condition called juvenile macular degeneration, ... describes how he adapted his athletic ambitions to his ... success in triathlon to pioneer the way for other ...
(Date:12/21/2014)... Concept Plus, LLC. a SDB and 8(a) certified IT ... today announced it has been recognized by Washington Technology as ... fastest growing government contracting small businesses by calculating their compound ... the first year that Concept Plus, LLC., participated in the ... compound annual growth rate. “For Concept Plus to be recognized ...
(Date:12/20/2014)... An improving macroeconomic landscape and a growing ... Massage Services industry over the five years to ... anticipated 1.0% annualized increase in per capita disposable income ... means to afford additional massages. “While the share of ... given year has declined from 2009 to 2012, this ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress wholesaler and ... for 2015. Great discounts are now offered on ... can get a discount, up to 80% off, when ... January 30, 2015. , VogueQueen.com has recently released its ... dress promotion. Many customers worldwide like VogueQueen’s special designs ...
Breaking Medicine News(10 mins):Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2
... - The Lancet Launches a New Initiative ... an Archive of Science for Health and Human,Development, ... the launch of a new, editorially,independent global health ... ., The network will search and archive ...
... 7, 2008 Varian, Inc.,(NasdaqGS: VARI) announced today ... owned company based in Abingdon, U.K. Oxford Diffraction,is ... used by,scientists in pharmaceutical research and other research ... and large molecules such as,proteins., For crystalline ...
... Schoolchildren who required surgery as infants for congenital ... having problems with inattention and hyperactivity, and often ... at risk for academic and behavior problems, and ... provide them with ongoing follow-up and neurodevelopmental screening, ...
... 2008 News stories about an allegedly harmful link ... onset of autism had little effect on whether U.S. ... immunization records and news stories. Parents decisions were more ... researchers said. , Researchers from The Children,s Hospital of ...
... Ingrid Bells turn at bat. She steps up to the plate, ... and connects with the ball. , Foul ball! Everyone cheers for ... a field, and theres no real bat or ball to be ... her occupational therapy. She is among 30 Parkinsons disease patients participating ...
... data of 221 men and women found that the ... death showed evidence of small, cumulative blood vessel damage ... Thomas Montine and colleagues analyzed the brain tissue of ... study, wherein 3,400 adult participants (65+) in the Seattle ...
Cached Medicine News:Health News:The Lancet Global Health Network 2Health News:The Lancet Global Health Network 3Health News:The Lancet Global Health Network 4Health News:Varian, Inc. Acquires Oxford Diffraction, Ltd. 2Health News:Varian, Inc. Acquires Oxford Diffraction, Ltd. 3Health News:For children with heart disease, a risk of attention and behavior problems 2Health News:Parents follow pediatrician advice on administering MMR vaccinations 2Health News:Parents follow pediatrician advice on administering MMR vaccinations 3Health News:Occupational therapists use Wii for Parkinson's study 2
(Date:12/17/2014)... and RALEIGH, N.C. ... Marketing Communications, LLC (CTMC), and Integrated Clinical Trial ... recruitment and retention for clinical trials announce that ... Clinical Trial Marketing Services (i-CTMS). i-CTMS will provide ... services to pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... 15, 2014 Registreer nu via  ... und 20. Februar sind alle akkreditierten pharmazeutischen ... ECOSYSTEM PARTNER PROGRAMM ™ 2015 in ... Diese Tagung soll dazu beitragen, der ... die neue profitablen Unternehmensdienstleistungen, die für Apotheken ...
(Date:12/15/2014)... 12, 2014 Research and Markets ( ... "Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, ... http://photos.prnewswire.com/prnh/20130307/600769 Global Electrocardiogram Devices ... 2016. The North America accounts ... while Europe claims approximately 27% ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4
... , SAN FRANCISCO, Jan. 11, 2010 Amylin Pharmaceuticals, ... priorities that will position the Company to address the dual ... by the end of the year and place the Company ... 2011. The news was presented by Daniel M. Bradbury, president ...
... , FRANKLIN LAKES, N.J., Jan. 11 ... today that it will conduct a live webcast of its first ... at 10:00 a.m. (ET). BD will issue a press release ... the conference call, along with related slides, will be accessible through ...
Cached Medicine Technology:Amylin Highlights 2010 Corporate Priorities at J.P. Morgan Healthcare Conference 2Amylin Highlights 2010 Corporate Priorities at J.P. Morgan Healthcare Conference 3BD Announces Live Webcast of First Fiscal Quarter Earnings Conference Call 2
... to facilitate an arthrodesis, either by an ... cages allowing radicular compression by restoring the ... of the foramina, which in turn enhances ... major lumbar instabilities.,CC cages are made of ...
... The PACHETT 3 uses the exact enhanced ... the DGH pachymeters used exclusively by the ... built into the software. The new backlit ... running average, standard deviation and IOP correction ...
... Already, the most advanced motor driven ... easier and faster to learn and operate. ... maintaining accuracy and precision. Our software makes ... easy transition from manual instruments or other ...
The Medmont C100 Colour Vision Tester is an electronic colour vision screening device which is used to rapidly detect red/green colour vision deficiencies. Its high sensitivity provides a positive in...
Medicine Products: