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Johns Hopkins researchers develop safer way to make induced pluripotent stem cells
Date:2/1/2011

so looked at the DNA from a dozen iPS cell lines to make sure there were no DNA rearrangements.

Cheng says the new method is also more efficient than the traditional use of skin cells to make iPS cells. "After a skin biopsy, it takes a full month to grow the skin cells before they are ready to be reprogrammed into iPS cells, unlike the blood cells that only need to grow for eight or nine days," says Cheng. "The time it takes to reprogram the iPS cells from blood cells is also shortened to two weeks, compared to the month it takes when using skin cells."

Cheng says "this easy method of generating integration-free human iPS cells from blood cells will accelerate their use in both research and future clinical applications."


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Contact: Vanessa McMains
vmcmain1@jhmi.edu
410-502-9410
Johns Hopkins Medical Institutions
Source:Eurekalert

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