Navigation Links
Johns Hopkins Evidence-based Practice Center awarded $475,000 project
Date:8/17/2011

An estimated $25 billion is spent annually on treating chronic wounds on patients in the United States. These chronic wounds deeply affect the quality of life of more than six million people who have them. The most common types of chronic skin wounds and skin ulcers are related to venous disease (conditions related to or caused by veins that become diseased or abnormal). Many treatment options are available, but the quality of evidence showing which treatments work better than others is often lacking. It is hard to prove which treatments are effective and should be the standards of care.

The Agency for Healthcare Research and Quality (AHRQ) awarded the Johns Hopkins Evidence-based Practice Center a $475,000 project to carry out an extensive research review and create a scientific report to inform health care providers about effective state-of-the-art wound care. Through this project, the Johns Hopkins Wound Center and the Johns Hopkins Evidence-based Practice Center are conducting an evidence-based review of wound care to determine what is known and unknown about it, and to establish strategies of care that are proved to work.

Gerald Lazarus, M.D., founder of the Johns Hopkins Wound Center, and professor of dermatology and medicine at Johns Hopkins Bayview Medical Center, and Jonathan Zenilman, M.D., newly named director of the Wound Center and professor of medicine and chief of the Division of Infectious Diseases at Johns Hopkins Bayview, are co-principal investigators of this study. Working with Eric Bass, M.D., MPH, director of the Johns Hopkins Evidence-based Practice Center, a team of recognized experts are trying to find important clinical answers to help treat patients with chronic wounds.

"This research is a unique and important study that underscores the scientific credibility and intellectual honesty of the Wound Center," says Dr. Lazarus. "It's a great example of how translational research affects everyday lives. The information we gather and present will help countless clinicians and patients to make better, more educated decisions about the best course of treatment to heal wounds."

This type of study, known as comparative effectiveness research, is done to inform health care decision makers by providing evidence on the effectiveness, benefits and risks of various treatment options. Johns Hopkins researchers will compile and analyze all of the evidence available from existing clinical trials, clinical studies, literature and research about chronic wound care. This research will determine the value of therapeutic interventions--such as medications, antibiotics, dressings and surgery--for healing chronic wounds.

A report will show health care providers, patients and others which treatments work best under certain conditions. The report will be designed as an important tool to understand the facts about different wound treatments. Its goal is to provide the best possible information about wound treatment choices that is easily usable so that health care providers can work with patients to make informed decisions about the right treatment plan for each wound.

Chronic wounds are a worldwide problem. Their prevalence and cost are increasing because of the aging population and more cases of obesity and diabetes worldwide. Chronic wounds often are associated with underlying conditions, such as diabetes, clogging of the arteries, diseases of the veins, neurological problems, consequences of rheumatological illnesses, inflammation of vessels and other medical difficulties. Wounds that will not heal are frequently signs of larger and more complicated health problems. Nonhealing wounds can take a toll on patients far beyond the pain and discomfort of the wound. They can cause patients to lose their mobility, which may lead to a decline in general health and emotional well being. Patients can become disabled, unable to work and depend on care from others.

"The topic of chronic venous ulcer treatments was nominated to AHRQ's Effective Health Care Program by a consumer and will be further developed by the Johns Hopkins Evidence-based Practice Center," said Christine Chang, M.D., MPH, medical officer of the Center for Outcomes and Evidence at the Agency for Healthcare Research and Quality. "The Johns Hopkins Evidence-based Practice Center is one of 14 centers in AHRQ's Evidence-based Practice Center Program, and has a core team with both clinical and systematic review expertise. It has assembled an excellent research team for this topic, and included individuals with extensive experience in the treatment and management of patients with chronic venous ulcers, as well as those skilled in systematic review methodology."

Dr. Chang adds, "While we do not formulate clinical practice guidelines, our hope is that this evidence report will provide patients and providers with the best information available to make well-informed decisions about care. The evidence report may also indicate areas of ongoing uncertainty, which will also be important as they consider various treatment options. We expect that clinician and consumer guides, as well as other translational materials, will be developed by our program, based upon the findings of the evidence report."


'/>"/>

Contact: Karen Tong
ktong4@jhmi.edu
410-550-0128
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. Johns Hopkins scientists map genes for common form of brain cancer
2. Johns Hopkins scientists begin first-of-its-kind research to create blood platelets from stem cells
3. Johns Hopkins researchers discover how some breast cancers alter their sensitivity to estrogen
4. Informed-consent forms should be shortened, simplified, Johns Hopkins bioethicists confirm
5. More focus needed on mental health triage in disaster preparedness, Johns Hopkins bioethicists urge
6. Johns Hopkins School of Medicine grants $5 million to study cognitive disorders
7. Johns Hopkins School of Medicine postdoctoral fellows win awards
8. Johns Hopkins researchers develop safer way to make induced pluripotent stem cells
9. Johns Hopkins scientists crack genetic code for form of pancreatic cancer
10. Hospital shootings rare, but rate of other assults high, Johns Hopkins researchers find
11. Johns Hopkins researchers turn off severe food allergies in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... ... protection and financial consultation services to families and business owners in the Dalton ... to raise support for children overcoming sexual assault and physical abuse. , The ...
(Date:7/21/2017)... ... July 21, 2017 , ... The Ellis Agency, an eastern Georgie ... Foundation in a community wide charity event with the goal of bringing in support ... local woman who lives with epilepsy, recently launched a charity campaign of her own ...
(Date:7/21/2017)... Helena, AL (PRWEB) , ... July 21, 2017 ... ... that offers insurance assistance and financial planning services to communities in the greater ... that promises to provide resources to underprivileged young people in the region. , ...
(Date:7/21/2017)... Grove, Ill. (PRWEB) , ... July 21, 2017 , ... ... & Fabric Liquid eco-friendly odor-control solution for colleges and universities at the ... safely and effectively eliminate severe cannabis and tobacco smoke odors without the use of ...
(Date:7/21/2017)... ... July 21, 2017 , ... Hospital M&A activity slowed in ... The number of hospital acquisitions rose to 23 in the second quarter, up 15% ... 15% from the 20 announced deals in the year-ago second quarter. Only four of ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... , July 13, 2017 RK Logistics Group, ... of Pharmacy certification for its Fremont, CA ... solutions in the Tri-Valley and San Jose ... City of Fremont , with its Fremont Innovation ... to provide such a powerful resource to the hundreds of ...
(Date:7/12/2017)...  Eli Lilly and Company (NYSE: LLY ) ... resolve pending patent litigation in the U.S. District Court for ... the Cialis ® (tadalafil) unit dose patent. This patent ... part of the agreement, Cialis exclusivity is now expected to ... "The unit dose patent for Cialis is valid and infringed ...
(Date:7/11/2017)... , July 11, 2017  The global market ... revenues of approximately $394.1 million in 2016.  Although in ... of solid growth, in particular as a result of ... practice, and the recent introduction of a significant number ... for less-invasive testing of tumor biomarkers to guide treatment ...
Breaking Medicine Technology: