Navigation Links
John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers
Date:12/7/2010

ous Stem Cell Transplantation (ASCT) in Multiple Myeloma. (Abstract number 38; oral session, December 5, 4:45 p.m. ET)

As lead author of a study by the Eastern Cooperative Oncology Group (ECOG), David S. Siegel, M.D., Ph.D., Co-Chief of Multiple Myeloma at the John Theurer Center, retrospectively analyzed data from the ECOG E4A03 trial. The earlier trial tested combination therapies for newly diagnosed multiple myeloma patients.

"We wanted to look at the effect of early autologous peripheral blood stem cell transplantation," said Dr. Siegel. "Transplantation in early-stage myeloma has become controversial because combination therapies with lenalidomide and dexamethasone have been shown to dramatically improve outcomes."

This transplantation technique, which uses a patient's own adult stem cells, has been a first-line treatment for patients who are newly diagnosed with this blood cancer. Multiple myeloma is a cancer that attacks plasma cells, which protect the body against disease and infection. It currently has a very poor prognosis.

Patients in the study were randomized to receive either lenalidomide with high-dose dexamethasone or lenalidomide with low-dose dexamethasone. After four rounds of treatment, patients had the option of continuing with drug therapy or receiving a stem cell transplant. For patients under the age of 65 who survived four cycles of treatment, overall survival at three years was 94 percent with early stem cell transplantation, vs. 78 percent for those who continued to receive a drug regimen instead.

"This analysis shows that the strategy of combining these medications followed by early adult stem cell transplantation has a remarkably good outcome and supports the continued role of early transplantation in the newly diagnosed," said Dr. Siegel. "Additional randomized trials on the timing of ASCT in myeloma may provide more answers on optimal treatment strategies."

Is Pra
'/>"/>

Contact: Amy Leahing
amy.leahing@gmail.com
305-458-0599
John Theurer Cancer Center
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. The John Theurer Cancer Center to unveil 40 presentations at the 52nd ASH Annual Meeting
2. John Theurer Cancer Center to present innovative research at 2 surgical meetings
3. John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system
4. John Theurer Cancer Center and LLS host panel discussion with leading hematologists
5. The John Theurer Cancer Center recognizes medical physics team for safety track record
6. John Theurer Cancer Center experts present new cancer research at ASCO Annual Meeting
7. Leading physicians and researchers at the John Theurer Cancer Center present research at ASCO
8. John Theurer Cancer Center offers breakthrough radiation measurement technology
9. John Theurer Cancer Center hosts hematologic malignancies program for physicians and patients
10. Low-dose aspirin reduces death rates from range of cancers by between 20 and 30 percent
11. Daily Aspirin Linked to Steep Drop in Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... in the April issue of Immunity , Kevin ... Medical Research, says it,s time to take a fresh ... sepsis, which kills millions worldwide every year, including ... released into the bloodstream to fight an injury or ... for maintaining good health without inflammation, wounds and ...
(Date:4/17/2014)... A Northwestern University synthetic biology team has created ... create programmable therapeutics that could travel the body ... disease. , Engineering cell-based, biological devices that monitor ... in clinical synthetic biology. However, no existing technology ... a patient,s physiological state and respond in a ...
(Date:4/17/2014)... Doctors who treat patients with a severe and ... an agonizing treatment decision. , The drug sirolimus ... relieve shortness of breath. But some patients eventually ... potentially fatal complications following transplantation. , "It,s a ... director of Loyola University Medical Center,s LAM Clinic ...
(Date:4/17/2014)... YORK, NY (April 16, 2014) The cause of ... a new study proposes that neurons may be mistaken ... immune system, similar to the way autoimmune diseases like ... the body,s cells. The study was published April 16, ... a new, and likely controversial, idea in Parkinson,s disease; ...
(Date:4/17/2014)... April 17, 2014 By discovering a new mechanism ... a stroke, researchers at UC Irvine and the Salk ... may limit or prevent stroke-induced brain damage. , A ... cause of death and primary reason for disability in ... a stroke and lets blood-borne material into the brain, ...
Breaking Medicine News(10 mins):Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Building 'smart' cell-based therapies 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:Is Parkinson's an autoimmune disease? 2Health News:Study IDs new cause of brain bleeding immediately after stroke 2
... An apple a day keeps the doctor away, yes; ... disease away as well//. Apple and apple juice were ... manner as medicines by researchers from the University of ... apple juice might increase the production in the brain ...
... Three years after the Centre for Science and Environment ... and a joint parliamentary committee endorsed it later// , ... again in 11 brands. ,Addressing a press conference ... by their pollution-monitoring laboratory has found pesticides in soft ...
... nutrition may be the best way to eat a lot during ... dietary details of about 7500, adults, researchers found that those who ... a larger quantity of food than those who consumed rich food. ... calorie count was much less than those who ate richer food. ...
... of people in UK expose themselves to the rays of the ... among cancer experts, who are rather troubled by this cream-free attitude.// ... and a record high temperature in July, it would indeed pay ... ,The trend is also because nearly 58% of the people do ...
... marijuana at the time of conception or in early ... to a new study in mice.// ,The author ... of pediatrics, cell and developmental biology and pharmacology at ... August issue of the Journal of Clinical Investigation. The ...
... of Tsunami 2004 is still fresh in the memory. There ... which ‘preparedness in adequate measure’ is considered extremely crucial.// It ... extended this sentiment in evolving suitable strategies against a potential ... German scientists will begin the exercise of delving into the ...
Cached Medicine News:Health News:Apple Juice May Keep Alzheimer's Away 2Health News:Marijuana Use Can Compromise Pregnancy 2
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com announces ... available in its catalogue: ... Drug Delivery Systems -- Focus on End ... STUDY OBJECTIVES A drug ...
(Date:1/15/2014)... 15, 2014  A novel wearable injector slightly larger than an ... patients to self-inject prescription drugs in the large doses required ... diseases, autoimmune deficiencies, and genetic disorders.  An ... by 2018, according to analysts.   Many of these drugs will ...
(Date:1/14/2014)... 14, 2014 InformEx, North America,s ... chemistry, will hold the 30 th edition of its ... Convention Center from January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ... pharmaceutical, fine chemical and specialty chemical companies will take part ...
Breaking Medicine Technology:Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2
... NUREMBERG, Germany, October 13 The German ... Mobile C-arms Business,Development Strategy Leadership Award" from the independent ... successful growth strategy,of the technology leader in the area ... up of important new markets, as well as the,securing ...
... WALTHAM, Mass., Oct. 13 According to Millennium Research ... intelligence, sustained economic growth since 2003 in Brazil, Russia, ... health care expenditures with an astounding $500 billion spent ... to diagnostic imaging scanners. Findings from MRG,s newest series ...
Cached Medicine Technology:Award-Winning Medical Technology From Germany 2Award-Winning Medical Technology From Germany 3$500 Billion Health Care Spend Boosts BRIC Countries' Diagnostic Imaging Sales Despite Global Recession, According to Millennium Research Group 2$500 Billion Health Care Spend Boosts BRIC Countries' Diagnostic Imaging Sales Despite Global Recession, According to Millennium Research Group 3
... newest member of the Xpect family, Xpect C. ... B in one rapid test. The simple-to-perform test ... in 20 minutes. ,The Remel Xpect family of ... of rapid, direct specimen tests that combine exceptional ...
Compact tray features all components for urethral catheterization....
... the Integrated Cytometry Solution offers a ... coupled with complete LIS connectivity. By ... sample undergoes - and managing the ... it delivers a progressive automated system ...
Convective Air Warming Blankets...
Medicine Products: